大

METHODS: Sixty healthy Sprague-Dawley rats were randomly divided into 3 groups: 6 rats in normal control group, 6 rats in EGb treating normal IOP group, and the other 48 rats were established chronic high IOP models of rats by cauterizing two episcleral veins. The n 30 rats satisfying experimental level were selected and randomly divided into five groups: 6 rats in physiological brine treating group, and the other 24 rats were divided into four experimental groups according to the dose of EGb: group A, EGb 50mg/; group B, EGb 100mg/; group C, EGb 150mg/; and group D EGb 200mg/. After the treating time of 1 month, the rats were sacrificed on schedule. Flat preparation of whole retinaes was stained distinctively and neuron counting in retinal ganglion cell layer from both eyes of each rat were performed to evaluate neuron situation.

取健康SD大鼠60只，正常对照组和正常银杏叶治疗组各6只，其余48只采用烧烙法，烙闭大鼠左眼2条浅层巩膜静脉，制作大鼠持续性高眼压模型，从中选出眼压稳定在实验要求水平的大鼠30只，随机分为生理盐水组，治疗A组（每日EGb 50mg/kg）、治疗B 组（每日EGb 100mg/kg）、治疗C 组（每日EGb 150mg/kg）、治疗D 组（每日EGb 200mg/kg），治疗时间为1mo，处死大鼠后做视网膜全层铺片，对RGCL神经元做特异性染色后行神经元计数分析来评估神经元的情况。

METHODS: Sixty healthy Sprague-Dawley rats were randomly divided into 3 groups: 6 rats in normal control group, 6 rats in EGb treating normal IOP group, and the other 48 rats were established chronic high IOP models of rats by cauterizing two episcleral veins. n 30 rats satisfying experimental level were selected and randomly divided into five groups: 6 rats in physiological brine treating group, and the other 24 rats were divided into four experimental groups according to the dose of EGb: group A, EGb 50mg/; group B, EGb 100mg/; group C, EGb 150mg/; and group D EGb 200mg/. After the treating time of 1 month, the rats were sacrificed on schedule. Flat preparation of whole retinaes was stained distinctively and neuron counting in retinal ganglion cell layer from both eyes of each rat were performed to evaluate neuron situation.

取健康SD大鼠60只，正常对照组和正常银杏叶组各6只，其余48只采用烧烙法，烙闭大鼠左眼2条浅层巩膜静脉，制作大鼠持续性高眼压模型，从中选出眼压稳定在实验要求水平的大鼠30只，随机分为生理盐水组，治疗A组（每日EGb 50mg/kg）、治疗B 组（每日EGb 100mg/kg）、治疗C 组（每日EGb 150mg/kg）、治疗D 组（每日EGb 200mg/kg），治疗时间为1mo，处死大鼠后做视网膜全层铺片，对RGCL神经元做特异性染色后行神经元计数来评估神经元的情况。

Objective To examine the value of Edaravone in the treatment of vascular dementia through ethologic and pathologic changes induced by chronic cerebral ischemiaMethods Wistar rats were randomly divided into sham operated group,model group,edaravone group and duxil groupThe chronic cerebral hypoperfusion models were made by permanent bilateral occlusion of both common carotid arteriesThe memory ability and ultramicrostructure of brain tissue were observedResults The escape latencies in model group were more significantly prolonged than that in the other groups (P＜005)But there was no significant difference between edaravone and duxil groupAnd pathologic changes observed by electron microscope in nerve cell of edaravone group and duxil group and model group were fairly light than that in sham operated groupEdaravone group had increased mitochondrium and frontal membranous synaptic vesicle and more productive metabolic activityConclusions Edaravone can lessen injures of hippocampal neurons loss to improve the spatial learning and memory abilitiesAnd it is proved further that edaravone can treat VD

目的 观察依达拉奉对慢性缺血致血管性痴呆大鼠行为学及形态学的影响，探讨依达拉奉在治疗VD中的应用价值。方法实验分假手术组、模型组及都可喜对照组及依达拉奉治疗组，应用双侧颈总动脉结扎方法制备慢性脑缺血大鼠痴呆模型，观察各组大鼠的记忆功能及脑组织超微结构改变。结果缺血组水迷宫表现同对照组、都可喜组及依达拉奉组相比有显著差异(P＜005)，依达拉奉组与都可喜组相比未见显著差异。同时电镜观察结果也发现依达拉奉组及都可喜组与模型组及假手术组相比神经细胞病理改变较轻，且依达拉奉组线粒体及前膜突触小泡增多，代谢活动较都可喜组旺盛。结论依达拉奉可能通过减轻海马神经元的损伤来改善慢性脑缺血大鼠空间学习记忆障碍，证明依达拉奉对慢性缺血致VD大鼠具有治疗作用。

To improve the economy, larger bypass ratio has been adopted in the turbofan engine design, leading to a larger fan high, larger speed gap between HP and LP turbines, the meridian geometry of the engine will be excurvature at a high degree, which brings problem for the design of LP turbines, transition section between HP and LP turbines.

在现代高性能的航空涡扇发动机设计中，为了提高经济性，采用较大涵道比，导致风扇高度增加较大，高低压涡轮转速差距较大，高低压过渡段采用大子午扩张型线结构，给低压涡轮及过渡段气动设计带来较大的困难。

Trial of acute toxicity: The mouse were given once the drugs of The root (10g/ml)and leaf (9g/ml) of Panicled Fameflower by irrigating gastric in largest volume (0.3ml/10g).

急性毒性实验：土人参根、叶水煎液浓缩制成的最大浓度(土人参根10g／ml，土人参叶9g／ml)给予小鼠最大容积(0.3ml／10g)一次灌胃，若小鼠死亡，则测定半数致死量LD_(50；若毒性很小，测不出半数致死量：则改用一日内以小鼠能耐受的最大浓度和最大容积，灌胃3次；测定其最大给药量。

The results show that, for the first with no headwall, when there is no crosswind, it has small front face areas, so the aerodynamic resistance is the least. Since the second and the third have headwall, the front face areas are large, so they have bigger aerodynamic resistance. Under the condition of crosswind, as the third design option has the highest side beam, the area of positive pressure at the upwind is bigger, and the area of negative pressure is smaller when the bigger eddy area appears, so the side forces become larger. The first has the least side forces; the overturning moment of the first is the least.

研究结果表明：在无横风情况下，方案一中没有端墙，迎风面积较小，受到的气动阻力最小，方案二和三中平车有端墙，迎风面积较大，受到的气动阻力也较大；有横风情况下，方案三中平车侧梁较高，车体迎风面正压区较大，而背风侧产生较大的涡流区，在此区域内压力较小，故其横向力较大，方案一中平车侧梁没有加高，受到的横向力最小；方案一中平车倾覆力矩最小，稳定性最好。

Despite evidence implicating prostaglandins as critical factor in male reproductive functions, little is known about expression and function of COX-2 in the male reproductive system. By using immunohistochemistry, RT-PCR and Western-blot, the content of this research included:(1) The expression and localization of COX-2 in mature rat and human testis were examined.(2) We investigated the changes of spermatogenesis and testosterone levels in testis after by using the COX-2 specific inhibitor-rofecoxib at 2, 4 and 8 weeks.(3) To explore the relationship between the intratesticular level of testosterone and expression of COX-2 by completely destroying the Leydig cells of mature male rats with injection of a single I.

本课题应用免疫组织化学、RT-PCR和Western-blot等方法检测以下内容：(1)在mRNA和蛋白水平检测正常成年男性及大鼠睾丸组织中COX-2的表达及定位情况；(2)实验组大鼠持续给予COX-2酶的特异性抑制剂Rofecoxib，分别于用药后2周、4周和8周检测大鼠的精子生成以及睾丸组织内睾酮浓度的变化；(3)另一组实验大鼠给予特异性Leydig细胞灭活剂EDS，在特定时间内抑制睾丸组织内合成的睾酮，于用药后2周和4周，采用免疫组织化学及RT-PCR方法观察大鼠睾丸组织内睾酮浓度变化对COX-2合成的影响。

China most summit of summit of knight-errant of China of combination of Le Tao of city of the toy on spread cables is gigantic make " world of sword a person adept in martial arts and given to chivalrous conduct ", from November 14 -- on December 14, roll out a theme to be jointly " old rotary table of sword a person adept in martial arts and given to chivalrous conduct, lucky Le Tao is cleaned out " activity of lucky big lottery, during the activity, all players should log onto page of theme of activity of lucky big lottery only, can jolty dial, participate in lottery activity, win freely take include strange helicopter of handkerchief of remote control A, dragon of remote control Xiang Yu the Conqueror, electronic drumstick, remote control corsair, stimulate guard against theft of beam of light to put cash pot, those who confuse you to catch the Le Tao such as baby machine to offer is numerous and rich and generous large award.

11月14日消息，中国最大线上玩具城乐淘(www.letao.com)和金山软件联合宣布：将斥巨资联合推动金山旗下网游《剑侠世界》的发展。有消息称：乐淘正秘密酝酿进军网游联合运营市场，首款产品就是即将展开合作的《剑侠世界》。中国最大线上玩具城乐淘联合中华武侠巅峰巨作《剑侠世界》，从11月14日——12月14日，共同推出主题为&剑侠大轮盘，幸运乐淘淘&的幸运大抽奖活动，在活动期间，所有玩家只要登录幸运大抽奖活动主题页面，即可摇动转盘，参与抽奖活动，免费赢取包括遥控阿帕奇直升机，遥控霸王龙，电子鼓槌，遥控海盗船，激光束防盗存钱罐，迷你抓娃娃机等乐淘提供的众多丰厚大奖。

In general, the relative size of IC was much larger in Microchiropteras than in Megachiropteras, and in echolocating Megachiroptera than in non-echolocating Megachiroptera.

结果表明：小蝙蝠IC的相对大小要比大蝙蝠的大的多，能够发超声的大蝙蝠的IC也比不能发超声的大蝙蝠的大。

Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果：(1)FSN有明显的抗炎作用，可显著抑制AA大鼠足跖肿胀与多关节炎，改善大鼠的全身情况，同时明显减轻病变关节滑膜炎症与增生，防止关节软骨及骨质的破坏，其综合作用优于TWP；(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常，纠正外周血中T细胞亚群Th／Ts及Th1／Th2平衡紊乱，抑制大鼠PHφ过高的TNF-α、IL-1分泌，而发挥抗炎和免疫调节作用；(3)在病变关节局部，FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达，降低滑膜组织中NF-kB表达，并增加凋亡蛋白酶Caspase-3表达，从而抑制滑膜的炎症与增殖；(4)FSN还可下调滑膜组织中VEGF表达，减少血管新生，由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀；(5)FSN的上述作用皆呈现一定的量效依赖关系，高剂量组作用优于低剂量组。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。