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The inhibin a gene、 the bone morphogenetic protein 4 (BMP4) gene and the bone morphogenetic protein 7 (BMP7) gene were studied as candidate genes on the prolificacy of Small Tail Han sheep. Single nucleotide polymorphisms of 5 ' regulatory region、 exon 1 of INHA gene;exon 2、 exon 3 and exon 4 of BMP4 gene and exon 2、 exon 3 of BMP7 were detected in high fecundity breed and low fecundity breeds (Chinese Merino sheep, Corriedale sheep and South African Mutton Merino sheep) by PCR-SSCP. The results indicated that there was a mutation (316C→T) in 5' region of INHA gene in Small Tail Han sheep, Chinese Merino sheep and Corriedale sheep, the same mutation did not exist in South African Mutton Merino sheep.

采用PCR-SSCP技术检测抑制素α(inhibin α,INHA)基因5'调控区、外显子1,骨形态发生蛋白4(bone morphogenetic protein 4,BMP4)基因外显子2、外显子3和外显子4以及骨形态发生蛋白7(bone morphogenetic protein 7,BMP7)基因外显子2和外显子3在高繁殖力绵羊品种以及低繁殖力绵羊品种(中国美利奴绵羊、考力代绵羊、南非肉用美利奴绵羊)中的单核苷酸多态性,同时研究这三个基因对小尾寒羊高繁殖力的影响。

There were 36 males and 40 females,with the average age of 47.7 years.36 patients presented with sciatica and perineal numbness,11 patients had painless mass and the other 20 were identified due to other causes.Among 67 benign neurogenic tumors,54 were originated from S1-S3 nerves,3 from S4-S5 nerves and 11 from the presacral space without caudal involvement.Giant cell tumor was found in 60 patients,which included 24 males and 36 females,with an average age of 32 years.Upper sacrum(S1-S2) was involved firstly.There were 56 patients(average,37.7 years) diagnosed as other primary benign bone tumors,which included 24 cases of teratomas,epidermoid cyst or dermoid cyst.Other malignant tumors,including chondrosarcoma (17),Ewing′s sarcoma/PNET(14),multiple myeloma(12),lymphoma(6) and osteosarcoma(6) were found in 64 patients.

其中脊索瘤95例,男62例,女33例,平均年龄55.7岁,骶尾区疼痛是主要症状(82例),半数以上患者伴有坐骨神经痛,肿瘤多先累及低位骶骨(S3~S5);神经源性肿瘤76例,男36例,女40例,平均年龄47.7岁,神经纤维瘤43例,神经鞘瘤24例,恶性神经鞘瘤9例,主诉多为坐骨神经痛、会阴部麻木(36例)和无痛性包块(11例),20例患者为查体或其他原因检查时发现,67例骶骨良性神经源性肿瘤起源于S3以上神经者54例,起源于S3以下神经者3例,发生于骶前未累及骶管者10例;骨巨细胞瘤60例,男24例,女36例,平均年龄32岁,腰骶尾部不适(37例)、坐骨神经痛(21例)是主要的临床表现,肿瘤多先累及上位骶骨(S1~S2);骶骨其他原发良性肿瘤及瘤样病变56例,包括畸胎瘤、皮样囊肿、表皮样囊肿共24例;其他原发恶性肿瘤64例,包括软骨肉瘤17例,尤文肉瘤14例,多发性骨髓瘤12例,成骨肉瘤6例等。

He expression of the multidrug resistance gene product P170 and the PCNA (proliferating cell nuclear antigen) was analyzed in 67 bone malignant tumours, 15 normal bone tissues and 15 exostosis by S-P method immunohistochemistry.

作者采用S-P法免疫组织化学染色技术观察67例恶性骨肿瘤组织、15例正常骨组织、15例骨软骨瘤组织中多药耐药基因产物P糖蛋白(简称P170)、增殖细胞核抗原的表达情况。

Haycock notes some oerweight children suffer foot pain from congenital or inherited foot conditions, such as bunions, hammertoes, pediatric flatfoot and tarsal coalition, an abnormal connection between two or more bones in the back of the foot.

Haycock指出一些超重儿童患有脚痛是由于遗传性或者先天的原因如拇囊炎、槌状脚趾、小儿平板脚和跗骨合并症,跗骨合并症主要是脚背面的两块或者更多的骨头异常结合在一起。

At present, autologous ilium and titanium-net cancellated bone are frequently used for clinical internal fixation, because both of them have good biocompatibility.

目前应用于临床的内固定植入物主要有自体髂骨和钛网松质骨植骨多见,生物相容性较好。

Effects of Psoralea corylifolia L.extract on the defensive enzymes on cucumber were studied and the results showed that activities of peroxidase,polyphenol oxidase, phenylalanine ammonialyaseof cucumber leaves were increased to highest level after 7 to 9 days at 40 mg/L and 400 mg/L.

补骨脂粗提物处理两叶一心生长期的黄瓜幼苗,补骨脂提取物在40mg/L和400mg/L浓度下,黄瓜体内过氧化物酶、多酚氧化酶、苯丙氨酸解氨酶等一些防御酶活性均在处理后7d~9d达最高。

In the mechanical test, 20 cadaveric humeri of children fixed with formaldehyde were divided randomly into 10 groups and the compressive, tensile and bending tests were conducted.

结果得出:①整骨试件不同,其断裂强度不同;髁上部的压缩、拉伸、弯曲强度低于骨干部和外科颈;断裂多在髁上部,且尺侧边缘骨皮质首先断裂。

Results Different signs of the lesions were demonstrated on X-ray plain film, such as locular,rough of bone trabecula and soap bubble-like changes ,frequently accompanied by dilatation of the mandibular nerve canal.

结果颌骨高流速血管畸形在X线平片上呈现多种表现,如囊状、骨小梁粗糙及&皂泡样&改变,多伴下颌神经管的扩张

Conclusion]ECT plays an important role in diaognosing the spinal tuberculosis and the tuberculose focus of body can be found and has the guidance for doctors to formulate the therapeutic regimem of spinal tuberculosis.

结论]核素全身骨显像在脊柱结核诊治中有重要价值,可以发现全身骨与关节多个结核病灶,对制定脊柱结核的治疗方案有指导作用。

Bone damage can be induced in rats fed with calcium-deficiency diet and fluoridized water in short term, with decreased calcium content, and the changes of chemical element in bone participate in the pathogenesis of fluorosis, and this suggestes that multiple factor is involved in the development of fluorosis.

染氟和低钙可导致大鼠骨损伤,骨中化学元素的改变参与了氟中毒的发病机制,说明氟骨症的形成是多因素作用的结果。

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