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In bicuspid and tricuspid valve, ECs were round or ovary, the ECs of lower surface of these valves were more apparent polarity than that of upper surface of the valve. The ECs appeared rectangle and arrange in regular, in pectinate muscles of left and right atrium, In inferior vena cava, ECs looked like round, ovary or irregular shape, without apparent polarity but with a few short microvilli.

在二尖瓣与三尖瓣,细胞多呈圆形或卵圆形,其瓣膜下面的细胞排列较上面的细胞极性明显;在左、右心房的梳状肌,细胞多呈长方形,排列较规则;在下腔静脉,细胞呈圆形,卵圆形或不规则形,极性不明显,有少量低矮的微绒毛。

Methods A randomized controlled trail was carried out in 41 patients. The medication design was based on the findings that the half life time of salvianolate was less than 2 h and its time of clearance uas 12 h. The treatment group (n=20) was treated with salvianolate at the dose of 200 mg, intravenous drip, twice a day, and the control group (n=21) with salvianolate at the dose of 200 mg, intravenous drip, once a day. The curative effects of salvianolate on angina pectoris (with syndrome of heart-blood obstruction) in the two groups was compared.

根据丹参酚酸B在体内半衰期小于2h,12h内药物基本从体内消除的研究结果设计给药方案,采用随机对照的方法,试验组(20例)丹参多酚酸盐200mg,静脉滴注,每日2次,对照组(21例)丹参多酚酸盐200mg,每天l次,比较两种给药方法对冠心病心绞痛的疗效差别。

AIM: To observe whether the behavior of polymorphonuclear leukocyte adhesion to the endothelial cell after trauma-hemorrhage and resuscitation is different between genders by means of intravital microscopy, and determine the expression of PMN adhesion molecule CD11b.

朱志宏,沈洪,李冰,田万管目的:在体实时观察创伤失血性休克复苏后微循环多形核白细胞在毛细血管后微静脉内皮的附壁是否存在性别差异,并测定多形核白细胞黏附因子CD11b的表达。

Methods Whole blood sample (2ml) acquired from 12 volunteers via a large antecubital vein was heparinized with 10U/ml heparin sodium and ice-bathed down to 4℃ and divided into the following groups: control group , PAF group , FMLP group, PAF+FMLP group , FMLP+lidocaine (10-4 M) group and lidocaine (10-4M,10-5M,10-6M )groups . the expression of CD11b in neutrophils was detected by flow cytometry in different groups .

选12名健康的成年志愿者,每位志愿者抽肘前静脉血2ml,肝素抗凝,置冰浴中降温至4℃分组如下:对照组,血小板活化因子组,趋化寡肽组,血小板活化因子+趋化寡肽, FMLP+利多卡因(10-4 M)组和P+F+利多卡因(10-4M,10-5M和10-6M)组,分别测定PMN CD11b的表达水平。

Creating chorioretinal venous anastomosis potentially offers a means of permanently bypassing the site of obstruction to venous outflow, to recovery the retinal blood circulation and to reduce the retinal ischemia. It is one of the methods curing the reason of CRVO and is demonstrated effective in non-ischemic CRVO patients using laser-induced chorioretinal venous anastomosis. Patients with ischemic CRVO have more severe situations and high risk factors of later neovascular complications occuring, the surgery of via a pars plana vitrctomy combined chorioretinal venous anastomosis can be the newest attempting treatment.

其发病机理和病因目前仍未完全阐明,也没有有效的治疗措施;除常规的药物和针对新生血管并发症的视网膜光凝治疗以外,近年来开展的各种旨在重建或恢复视网膜血液循环的激光和手术治疗方法正日益成为眼科界关注的焦点;利用建立脉络膜视网膜静脉吻合途径,使被淤滞的静脉血流经由脉络膜血管流出眼外,促进或者恢复视网膜血液循环,减少视网膜缺血缺氧状态的发生,是多途径CRVO对因治疗的方法之一。

Huge hepatocellular carcinoma, hepatic artery to hepatic vein fistulous, and an overdose of lipidol are risk factors of PLE, which can be reduced by exactitude and precise operation during TACE.

初步研究结果提示,碘油肺栓塞常发生在巨块型肝癌,且多存在肝动脉-肝静脉瘘,碘油用量多>20mL,术中正确处理可减少此类并发症的发生。

Intralobar pulmonary sequestration usually present as multiloculated cyst containing fluid and/or air, or irregular mass in CT scan, multi-slice CT angiography and 3D reconstruction can depict supplying artery and draining vein clearly, so it could be an ideal modality for evaluating this condition.

叶内型肺隔离症多表现为下肺基底段的多房液气囊腔或者不规则团块,多层螺旋CT血管造影及三维重建能清晰显示供血动脉及回流静脉,是一种理想的无创性检查方法。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周,炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节,另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg,20分钟后踝关节照光,激光波长627.sum,功率密度 100mwcm',照射时间1000秒,能量密度100)/。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径,治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后,治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗,随机治疗一侧膝关节,另一侧作自身对照。兔耳静脉注入I'arrainrelomg/Kg,20分钟后,膝关节用金蒸气激光照射,激光能量密度100)儿旷。24 /J'时后取膝关节滑膜作病理检查,并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果: 1。模型观察:CIA大鼠炎症高峰期滑膜下炎细胞浸润明显,滑膜细胞明显增殖,炎症达到高峰后二周,血管缀形成,并侵蚀和破坏软骨和骨, CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生,滑膜下炎细胞浸润,也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明,各组织对HMME 的吸收速度和吸收量不同,荧光值一时间曲线不同,滑膜组织比皮肤和软骨对 HMME的吸收多,在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明:PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性,但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好,统计学检验差异有显著性。。3_军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少,图像分析结果表明面密度(阳性染色的面积总和与统计视野面积的比值)治疗组小于对照组,统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多,图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组,统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小,与对照组相比,统计学检验差异有显著性。结论:二。CIA、AIA的病理改变类似人类RA,可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同,滑膜组织比皮。

Connective tissue is proliferous all round blood-vessel of place of mouth of A group be identical relatively B group is little, relatively C group is much.

结果A组动脉化的静脉壁中膜平滑肌较B组的多,而呈圆形内皮细胞核均较B组少。A组吻合口处血管四周结缔组织增生较B组少,较C组多。

Methods: Forty-three indiviuals who were exposed to arsenic more than 0.05mg/L in well water were chosen and the vein blood and morning urine was collected; The MTHFR C677 polymorphism was analyzed by PCR-RFLP method; Urinary inorganic and methylated arsenic were speciated by high performance liquid chromatography combined with hydride-generation atomic fluorescence spectrometry; Microbiological assay was used to estimate serum folate.

在砷中毒流行区选择饮水史清楚、饮水砷含量高于0.05mg/L的43名居民,采集空腹静脉血并收集晨尿,以聚合酶链反应-限制性长度多态性方法分析MTHFR基因C677T位点多态性,采用高效液相色谱-氢化物发生-原子荧光法检测尿中各种形态的砷,采用微生物法测定血清中叶酸水平。

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