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The patients expressing ER have a better prognosis than ER negative patients,because of lower incidence of microsatillites,and extracapsular invasion,lowerPCNA LI and early stage.

3,由于ER阳性的肝癌多有完整的包膜、较低的子结节或卫星灶伴发率以及较低的PCNA标记指数,提示其预后要好于ER阴性的肝癌。

In this case, severe atherosclerosis in a patient with diabetes mellitus led to severe aortic atherosclerosis with renal arterial stenosis as well as nephrosclerosis and nodular glomerulosclerosis of the kidneys.

这是一个伴有严重的动脉硬化症糖尿病患者的标本,患者有严重的大动脉硬化症、肾细动脉狭窄和硬化及肾结节性多动脉炎。

Adenoma: from glandular occurred benign mucous gland adenoma mostly polypoidal, glandular organ within the adenoma were nodular, and often coated with the surrounding normal tissue clear boundaries, structure and start glands are very similar, often with a certain degree of secretory function, can secrete serous and mucinous, commonly found in the thyroid, salivary gland, ovarian, breast, etc..

腺瘤:由腺上皮发生的良性肿瘤,粘膜腺的腺瘤多呈息肉状,腺器官内腺瘤呈结节状,且常有包膜,与周围正常组织分界清晰,结构与起始腺体十分相似,常具有一定的分泌功能,能分泌浆液和粘液,常见于甲状腺、涎腺、卵巢、乳腺等处。

GnRH-ir fibers distribute in the various brain region from the olfactory bulb to the cerebellum. They are especially abundant in the hypothalamus, the preoptic area and the ventral telecephalon. The immunopositive reaction in precocious fish is evidently stronger than that in unprecocious fish, and there is only very weak reaction in the gonadal undeveloped fish. The differences are most obvious in the hypothalamus, but not in other areas.

性早熟大黄鱼的神经内分泌细胞对GnRH抗血清的免疫阳性反应明显,无论在细胞的数量和免疫强度都比未早熟鱼多和强,在性腺尚未发育的幼鱼脑中仅有弱的免疫阳性,这种差异在下丘脑外侧结节核及视前核处最为明显,在其它GnRH阳性部位则差异不显著。

Histologically, the seminiferous tubules contained numerous Sertoli cells and more Sertoli-spermatozoa complexes, accompanied by the depletion of Leydig cells with deeply stained nuclei. Mature spermatozoa were stored up in the epididymis, but only a few in the efferent ducts. In the second place was testicular atrophy(32/120; 26.7%). The seminiferous tubules showed moderate to severe inactivity of spermiogenesis with evidence of only spermatogonia, spermatocytes and Sertoli cells. The Leydig cells were obviously decreased in numbers associated with decrease of lipid droplets in their cytoplasms. Testicular hypoplasia was the third disorders(22/120; 18.3%). Only a few spermatogonia and Sertoli cells appeared without any spermiogenesis. The associated changes was decreased in Leydig cells and fibrous hyperplasia in the interstitium.Epididymal stones were sometimes found(12/120; 10%). Grossly, yellowish-white nodules with various sizes and firm in consistency were observed in the epididymis and the front efferent ducts. Microscopically, the epididymal ducts were dilated with voluminous spermatozoa storage, even showed calcification in severe cases. The deposited calcium salts were stained positively by Von Kossa and Alizarin red methods.Amyloidosis was also detected in 10 roosters(8.3%). Eosinophilic, homogeneous, amyloid-like substances were deposited mainly in the testicular interstitium and the periphery of blood vessels. These substances showed positive reaction by Congo red staining. Five roosters(4.2%)had Marek's lesions in the testis, epididymis and peripheral nerves with infiltration of pleomorphic lymphocytes. Only one case showed epithelial necrosis of seminiferous tubules accompanied by fibrous proliferation in the interstitium.

结果发现,在总共搜集的120个病例中,其中因年老所导致的产精力不佳为最多,占38例(31.7%),於镜下可见大量精虫黏附於Sertoli cell的表面,并可见Sertoli cell数量明显增多而Leydig cell明显减少,且其细胞核呈现浓染的现象,而在其副睪中仍可见到成熟精虫蓄留於管腔中,但在其输精管内却只有少量精虫存在;其次为睪丸萎缩,占32例(26.7%),镜下可见中度至重度无造精作用,其生精小管中只见到精母细胞、精原细胞及Sertoli cell存在,但Leydig cell数量明显减少且其细胞质内的脂质也明显减少;睪丸发育不全,占22例(18.3%),於生精小管内只见到精母细胞及少量Sertoli cell存在,不见造精细胞分化,於生精小管间质可见Leydig cell减少并伴随结缔组织增生;副睪结石,占12例(10%),肉眼下可在副睪及输精管前段见到黄白色大小不一的结节,触感坚硬,於镜下可见副睪管扩张并有大量成熟精虫蓄积,严重时可见钙化现象,以Von Kossa及茜素红染色均呈阳性反应;类淀粉沉著症,占10例(8.3%),镜下在睪丸间质及血管周围可见粉红均质样的物质沉积,以刚果红染色成阳性反应;马立克病,占5例(4.2%),镜下可在睪丸、副睪实质及周边神经内均可见到嗜碱性大小不一的淋巴样细胞浸润;睪丸坏死,占1例(0.8%),镜下可见生精小管上皮细胞坏死脱落及间质结缔组织增生。

Acne generally has no symptoms and can self-cure without being treated.

本病多发于面部、胸部、背部等皮脂腺丰富的部位,单纯的痤疮多无任何症状,不经治疗即可自愈,而有些患者过于焦虑和紧张,当粉刺发生感染时,即变为红色丘疹及脓疱,感染较重则出现结节、囊肿和窦道,可遗留萎缩性瘢痕。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。