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Cells in medullary carcinomas of thyroid gland can appear very pleomorphic or spindled, but there usually are better differentiated cells with neuroendocrine fetaures with or without amyloid, calcification, and giant cell reaction.

甲状腺髓样癌的细胞可能显示明显的多形性和梭形细胞样,但通常有分化较好的细胞伴神经内分泌特征,伴或不伴淀粉样变、钙化和巨细胞反应。

A human MDRl full length cDNA probe was used to screen a pufferfish cosmid library and nine clones, which would contain the whole MDR gene family in the pufferfish genome, were finally identified. One of the cosmid clones was sequenced. Sequence analysis revealed that there would be at least three MDR homologues in the corresponding region.

其表达产物为一跨膜蛋白p-glycoprotein,通过ATP提供能量,将进入细胞内的多种物质泵出细胞外,从而使细胞对这些物质产生耐药性,多药耐药基因的功能决定了它在肿瘤化疗中的位置而使其成为基因结构、功能和表达、调控研究中的热点。

Results. Pleiotrophin immunoreactiity was seen in disc cells, endothelial cells, and in the extracellular matrix in most specimens of interertebral disc but was most prealent in ascularized tissue in prolapsed discs.

结果:多效蛋白表达在大多数标本的椎间盘细胞、内皮细胞和细胞外基质都得到了较好的表达,但表达最显著的还是在突出椎间盘的血管再生组织中。

These were raised underinducing condition to test if any morphology and structure changes. Twenty two Arabidopsismutants had various changes in morphology and anatomical structures. Twenty mutants hadlow germination rate from 10% to 60%, of which 2 had survival rates at 0% and 50%. Fivemutants occurred structure changes in the hypocotyls or stem. One of these lines, namedarris-stem, showed some unique changes: slower growth rate in comparison with the wildtype from germination to florescence; serrated margin of leaf blades, spiral rosette; morebranch in the bottom part of the stem, shorter nodes, twisted stem and branch. There were oneor several arrises along the stem. Across sections of the arrises showed one or several compactcells lumps which were round, made up of several layers of cells, looked like vascular-bundle.

在诱导条件下,这些突变体表现出不同的形态和结构的变化,共有22个表型和结构发生变化。20个突变系发芽率或存活率较低,发芽率由10%—60%,其中2个突变系存活率分别为0%和50%。5个突变系在茎或下胚轴的结构上发生变化,其中一个突变系arris-stem发生如下表型变化:从真叶出现至开花结实的整个生长期,生长速度要明显比野生型拟南芥缓慢;叶缘有明显锯齿,莲座叶呈螺旋状排列;茎的基部有较多侧枝,侧枝间距明显缩短,茎有明显扭曲;突变体茎侧面有1至数条棱形突起,内部存在一至数个排列紧密的细胞团,由多层细胞呈环形排列,细胞壁明显加厚,内部存在管状分子,推测为维管组织。

The ciliates were always ideal materials in the studies of the structure and function of cytoskeleton and its cell control and adjustment, for they have many kinds of cytoskeletons with complexity and they could be easily cultured and handled.

由于原生动物纤毛虫具有多种复杂的细胞骨架结构,加之其材料培养和处理的优点,一直被作为研究细胞骨架结构与功能及其细胞调控的理想材料。20世纪80年代初,许多学者应用蛋白银染色方法和超微结构方法,显示了纤毛虫细胞皮层中以纤毛基体作为主成分的骨架结构,探讨了纤毛虫皮层纤毛器的形态、形态发生及其结构形成机理,在国内外原生动物细胞学领域成为主流。20世纪90年代起,先后应用非离子去垢剂处理和扫描电镜相结合的方法、稳定保存微管结构的透射电镜术,微管蛋白的抗体标记及其免疫荧光技术及相关的生化与分子生物学等方法显示纤毛虫的微管胞器及其微管蛋白组分,探索微管胞器的形态、功能及其微管装配机理,积累了较多的资料,取得了重要的进展。

The results showed that, after induced for 4~5 d by dexamethasone, beta-glycerophosphate and ascorbate-2 phosphate, the volume of some cells of the goat MSCs gradually largened and changed their form from spindle/polygon to cuboid/ovoid; With the induce time continuing, the numbers of the cuboid/ovoid cells continuous increased; At 15th day, there were many cuboid cells, and the modality of the cells changed from cuboid to ovoid; At 25th day, the oval and cuboid cells accumulation were observed.

结果表明,山羊MSCs在地塞米松、β-磷酸甘油和抗坏血酸的作用下,从诱导的第4~5天开始,即可见有些MSCs体积逐渐增大,由梭形或多角形转变为立方形或卵圆形;随着诱导时间延长,立方形或卵圆形细胞不断增多,到第15天时,有较多的立方形细胞,且这种变化经历了从立方形向卵圆形转变的过程;第25天,可见卵圆形和方形细胞堆积,诱导分化率为90.2%± 2.97%。

The cell in acidic situation presented a degenerative chang-ment,such as an increased lipid drop and empty cavity in the cell plasma,a py-knotic nuclei,the dilatation of the endoplasmic reticulum and Golgi saccules,mi-tochondrial swelling the number of ribose decrease,and the ribose dissociated inthe plasma,a lot of swallowing cavity,the fibric material decreased accompany-ing with the acid being stronger.

随培养基pH逐渐下降,上述过程因受酸性阻抑而延缓,细胞增殖速度也受影响,处于酸性环境中的软骨细胞呈退行性变化,表现为细胞浆内脂质颗粒与小泡增多、细胞核皱缩、核仁浓染、内质网线粒体膨胀、核糖体数目减少,且与粗面内质网结合的少,游离在胞浆中的多。

Complicated than procaryotes. These cells, exemplified by the yeast in Figure 4.1-3, have a membrane surrounding the cell which is similar in structure to the procaryote membrane.

真核细胞,具有真正的细胞核,其结构要比原核生物复杂的多,以图4.1-3中所示的酵母菌为例,和原核细胞一样真核细胞也具有一层细胞膜。

A multi-epitope antigen gene pcx was assembled by five highly conserved B-and/or T-cell epitopes, which were selected from C (1-16aa, 132-141aa), E1 (126-135aa), NS3 (139-147aa) and NS5B (768-775aa) protein, as well as a T-cell epitope of tetanus toxin, which was added to enhance T-cell immunity.

针对HCV的高度变异性及免疫特点,在HCV基因产物中优选了5个具有良好免疫原性的高度保守B/T细胞表位,组合成一个多表位抗原基因pcx,这些表位分别来自核心蛋白(1~16aa,132~141aa),E1(126~135aa),NS3(139~147aa)及NS5B(768~775aa),以及破伤风毒素的T细胞表位用以增强T细胞免疫。

Restriction mechanism for fiber elongation of Lil mutant grown in Held There were abnormities of ultra structure in 9 DPA fibers of Lil mutant whencompared with wild type: thinner cytoplasm, less functional organelles such as Golgi body and endoplasmic reticulum, ect, and more starch grains.

在田间条件下突变体纤维伸长受抑制的原因与野生型比较,突变体开花9d后的纤维细胞在细胞形态学上存在异常:细胞质染色较浅,各种功能性细胞器如高尔基体、内质网等少,有较多的淀粉粒等。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。