多细胞动物

Fabrication of tissue section:after spinal cord injury ld,3d,5d,8d,14d,21d,we sacrificed rats in batch.4% formaldehydum polymerisatum were pured into the cardiac muscle and fixed for 24h.Then obtain the specimen of spinal cord from T_5 to T_(13).Establishing slices,HE dyeing,bcl-2 dectation,terminal doxynucleotidyl transferase-mediated dUTP nick end labeling.On the fourteenth day after spinal cord injury,we detect Gale grading score and tiltboard experiment.

组织切片的制备：脊髓损伤后1d，3d，5d，8d，14d，21d共6个时间段分批处死动物。4%多聚甲醛心肌灌注固定24h，切取每只大鼠T_5～T_(13)节段脊髓组织，常规制成切片，给于HE染色，Bcl-2检测，TUNEL原位末端标记以及伤后第14天检测Gale评分和斜板实验，检测大鼠脊髓损伤后细胞凋亡和脊髓神经功能恢复情况。

But to make a true clone a cell needs to be not just pluripotent, but totipotent and thus able to turn into an entire animal.

但是为制作真正的克隆，一个细胞不仅要是多功能的，还必须是全能的，进而能转化成完整的动物。

objective to study the effects of coadministration of aspirin with erythromycin ethylsuccinate on liver microsomal cytochrome p450 isoenzyme and multidrug resistance gene in rats.

目的以大鼠作为实验动物，形成疾病模型，研究阿司匹林合用琥乙红霉素对大鼠肝脏细胞色素p450同工酶和多药耐药基因的影响。

Only in adulthood the inability of these neurons to receie GDNF due to the missing receptor became eident and the older the animals grew, the more nere cells died.

仅仅在成熟期间随着这些神经元因失去受体变的明显并且动物长的越老，细胞的死亡越多从而无力接受GDNF 。

Human neurotropic JC virus is able to infect human brain glial cells. The causative agent of the fatal human demyelinating disease progressive multifocal leukoencephalopathy, that cytolyses and destroys oligodendrocytes, the myelin-producing cells of the central nervous system. Also results from several experiments have indicated the JCV is able to induce neoplasms.

人类嗜神经性JC病毒可感染人类脑细胞是引起进行性多病灶脑白质病的因素，为一种致命性的脱髓鞘疾病，其导致神经系统产髓质细胞的溶解破坏，但JCV也在许多动物实验上显示其有促成肿瘤的潜在性。

According to the above study result, the diversity of microorganisms population in the SUFR system is complex and the bio-community formed in the SUFR system is stable. The close relations between abundance of bacteria and nutrients were found. The correlation between heterotrophic bacteria and COD was 0.949. The correlation between organic phosphate bacteria and TP was 0.815. The correlation between nitrosobacteria and NH3-N was 0.909. The correlation between disnitrifier bacteria and TN was 0.653. These inneglectable great factors effecting on phosphorus-uptake and phosphorus-release of phosphorus accumulating organisms are the influent COD、the concentration of DO、the sludge retention time、the temperature. The diversity of organic phosphate bacteria population in the SUFR reactor was complex and there is no phosphate bacteria taking the absolute superiority in quantity. The near-native pure culture method powerfully complement the traditional pure culture technique and enrich culture technique. The sludgy bioactivity is very good in whole SUFR reactor. By the quality of being biochemistry, the anaerobic phase is higher than anoxic phase and the anoxic phase is higher than aerobic phase of SUFR.

通过以上试验内容研究发现，SUFR 系统中的微型动物种群较多，微生物生态系统稳定；系统中微生物的数量与营养盐的含量密切相关，其中总异养菌与COD的相关系数r 为0.949，有机磷细菌与TP 的相关系数r 为0.815，亚硝化菌与NH4+-N的相关系数r 为0.909，反硝化菌的数量和TN 的相关系数r 为0.653；污水生物除磷工艺中进水COD 的浓度、DO 浓度、泥龄的长短、温度都是影响聚磷菌释磷及吸磷效果的不可忽视的因素；SUFR 系统中的磷细菌呈现种群多样化的趋势，没有占绝对优势数量的磷细菌；微孔滤膜近自然培养法是对传统纯培养技术和富集培养技术的有力补充；整个SUFR 反应器系统中污泥的生物活性很好，就可生化性来讲，厌氧反应器大于缺氧反应器大于好氧反应器；按照动力学方程式求出的细胞生长动力学特征值和SUFR 脱氮除磷系统工艺的实测值结果基本吻合。

New antifungal agents have been developed over the past years based on the discovery of many new target sites of Candida albicands. For example, Echinocandins, aiming at the cell wall of Candida albicands, showed strong antifungal activities to fluconazole resistant candidas and fungal biofilm. Moreover, because β-glucan synthase does not exist on the cell membrane of mammalian cells, Echinocandins has a low toxicity and a promising clinical future. Though the mechanism of Histatin is not clear, it has strong activity not only on candida resistant of polyene and azole, but also to Candida parapsilosis, Candida krusei and Cry ptococcus neoformans. Berberine and Ocimum gratissimum L. were also found to have prominent anti-fungi activities.

近年来相继提出了许多抗白念珠菌药物作用的新靶点并成功开发出一些活性强大，疗效确切的抗真菌药，如以真菌细胞壁为靶点开发出棘白菌素类药物卡泊芬净、米卡芬净等，该类药物主要抑制β-葡聚糖合成酶，体外对氟康唑耐药的念珠菌属及真菌生物被膜表现出强大的抗菌活性，又由于β-葡聚糖合成酶在哺乳类动物细胞内不存在，故具有高效低毒的临床效果，是一极具前途的新型抗真菌药；以真菌细胞膜为靶点开发出Histatin类药物，虽然作用机制目前还不完全明了，但其作用不同于临床常用的多烯类和氮唑类，并已经发现Histatin5对两性霉素B和氮唑类耐药的念珠菌有效，并且对非白念珠菌如光滑念珠菌、克柔氏念株菌、隐球菌等也有杀灭作用；通过对植物药物的研究发现黄连素和丁香罗勒Ocimum gratissimum L。

Results The NASH rats showed increased CYP Ⅱ E1 immunostaining, especially in the perivenous region.

结果NASH模型组动物CYP ⅡE_1阳性细胞显著增加；且多在中央静脉周围，这与肝脂肪性变趋于一致。

Hill-reservoir has a short retention time; its phytoplankton community was characterized by low abundance and no obviously dominant species. The zooplankton was predominated numerically by rotifer and nauplii.

山地型水库具有较明显的河流特征，浮游植物的种类数和细胞密度均较低，有较多的河流种，无明显优势种；浮游动物的种类和数量很低，以轮虫和桡足类幼体为主。

In addition, under appropriate culture conditions, ES cells differentiate into a broad spectrum of cell types and when injected into immunocompromised animals, they form teratomas composed of multiple lineages.

此外，在适当的培养条件下，胚胎干细胞分化成多种细胞类型，当注入免疫功能低下的动物，它们的形式组成的畸胎瘤多个系。

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。