多等位基因

Homozygosity; He: Heterozygosity; Ne: Effective number of alleles; PIC: Polymorphism information content.

遗传纯合度； He：遗传杂合度； Ne：有效等位基因数； PIC：多态信息含量。

Objective: Association research of Chinese Han chronic obstructive pulmonary disease and human leucocyte antigen.

目的：探索我国汉族人群人类白细胞抗原等位基因多态性与慢性阻塞性肺疾病的易感性。

All loci detected in the study showed polymorphism and the number of alleles ranged from 2 to 22 in total population.

在所检测的4个群体中，各群体均有较高的多态性，其杂合度都超过了0.55，各位点等位基因的数目为2~22。

The ratio of one-step gain versus loss was 1.826:1. There was only one multiple-step mutation with a double-repeat gain observed at PentaD locus.

只发现1例多步突变，表现为PentaD位点的等位基因的增加2个重复单位。

The statistical effect of sampling error during the reproduction of alleles is much greater in small populations than in large ones.

在等位基因复制期间，抽样误差的统计学效果对小群体的影响比对大群体的影响大得多。

The result showed that: 148 poly morphic hands were detected by use of, 22 RAPD primer and 158 allele were detected by use of 34 SSR primer.

利用筛选出的22条RAPD引物，检测到了148条有多态性的带；利用筛选出的34对SSR引物，检测到158个等位基因。

This effect may be more notable in those who hae one or more APOE epsilon4 alleles.

这种效应在那些具有一个或多个APOE ε4等位基因的人中更明显。

The 30 microsatellite loci are vised in this experiment to analysis the genetic diversity of six sheep breeds in order to offer basis of use and protection of sheep genetics.1 The 30 microsatellite loci which are selected from 41 published ones show polymorphism.

本文利用30个微卫星标记对6个绵羊品种的遗传多样性进行了分析和研究。旨在为绵羊遗传资源的合理利用及保护提供科学依据。 1 从已发表的41个绵羊微卫星位点中筛选出在本实验的6个绵羊品种中表现出多态性的30个位点，共检测到284个等位基因。

The plum-apricot germplasm resources were analyzed by RAPD markers. The results showed that plum-apricot was more close to the related species with low polymorphism. The clustering results were indicated that most plum-apricots were more close to Chinese plum with the similarity of morphological description, thus the female parent for plum-apricot was probably plum in the occurrence naturally. The result of S allele-specific PCR amplification showed that plum-apricot had only one band with the similarity with plum, thus evolution similarity of plum-apricot was more close to plum than apricot.

5对参试杏梅种质资源的RAPD分析表明，杏梅与其近缘种之间亲缘关系较近，多态性相对较少；聚类分析结果显示大部分的杏梅与中国李的遗传距离较近，与形态学上的描述基本一致，因此杏梅种质资源在自然界中产生时，其母本可能为李；同时S等位基因的扩增结果显示杏梅与李的扩增条数一致，都为一条，因此推断杏梅与李的进化趋同性可能较杏更近。

A referencing flock comprsing eight paternal half-sib families totaling 374 individuals from Liangshan semi-fine wool sheep was utilised to analyze the allele frequency, polymorphism information content and heterozygosity of nine microsatellite from 2~ chromosome of sheep genome.And the research based on the daughter design to locate the putative QTL affecting wool traits was carried out in the linkage framework-mapping of 2~ chromosome.

本研究利用凉山半细毛羊的8个父系半同胞家系共374个个体，分析了绵羊基因组2号染色体上9个微卫星标记的等位基因频率、多态信息含量和群体杂合度，利用已构建的凉山半细毛羊2号染色体遗传连锁框架图谱，采用女儿设计对影响凉山半细毛羊8个羊毛性状的数量性状位点进行了定位研究。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。