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LTA gene +252A/G polymorphism space point G allele frequency showed no significant difference.

LTA基因+252 A/G多态性位点G等位基因频率差异不显著。

The T allele confers protection against the onset of T2DM only in homozygosity and may serve as a recessive trait.

结论① TAFI1040C/T基因多态性与T2DM患病危险度存在关联;② T等位基因可能在T2DM早期病情进展中起保护性作用。

Objective To explore the hereditary susceptibility of HLA-DRB1 and-DQB1 alleles of epidemic hemorrhagic fever at gene level and to further the features of their immunogenetics.

目的 从基因水平探讨HLA-DRB1、DQB1等位基因多态性与流行性出血热的相关性,以阐述其免疫遗传学特征。

Different allels mey be acquired within the invented segment after the inversion poly morphism is established.

在倒位多形性形成后,在倒位的区段内可能获得不同的等位基因。

It generally occurs when there are two or more allelic forms of a major gene in a population.

当种群中的主要基因具有两个或多个等位基因类型时,不连续变异可以发生。

TaqIB polymorphism possibly contributed to cerebrocardiac vascular disease.The accidents of cardiovascular disease in B1B1 type was the highest in three genotypes while the accidents of cerebrovascular disease in B1B2 type was the highest.B2 allel gene has probably protective effect on cerebrocardiac artery.

TaqIB基因多态性与心脑血管事件发生可能有关,B1B1型心血管事件发生率较高,B1B2型脑血管事件发生率较高,B2B2型心脑血管事件发生率均较低,B2等位基因可能具有心脑血管保护作用。

Three microsatellite loci were used with four quail(Coturnix spp.) populations at their DNA level,in East China for the detection of genetic diversity of the no genetic relationship resources.

在DNA水平上检测了华东地区4个亲源关系不同的鹌鹑群体的3个微卫星座位遗传变异,每一位点均检测到4~5个等位基因,各位点的基因多态比例接近100%。

To detect QTL for the body fat-related carcass traits in beef cattle, the single strand conformation polymorphism assay was used for investigating the K232A substitution in DGAT1. Animals from 4 beef cattle populations (32 Luxi, 28 Jinnan, 32 Qinchuan and 26 Limousin × Luxi cattle) were used to estimate allele frequencies and gene substitution effects on several beef carcass traits.

为研究肉牛与体脂相关的胴体性状的数量性状座位,利用单链构象多态性方法检测了牛DGAT1基因K232A取代的2个等位基因K和A在实验群体中的分布频率,并分析了基因型对4个肉牛群体部分胴体性状的影响。

Methods The genotype of 4 SNPs in 108 simple CHD patients and 200 normal people were analyzed by restriction fragment length polymorphism and denaturing high-performance liquid chromatography. The statistical contingency table method was used to analyze SNP genotype frequency and gene frequency in patients and control group;then, the haplotypes were established and their frequencies in the two groups were assessed by PHASE software.

方法应用限制性片段长度多态性和变性高效液相色谱法结合测序,分析108例单纯性先天性心脏病患者及200名正常人4个SNP位点基因型;应用列联表法统计分析患者组和对照组各SNP位点基因型及等位基因频率;应用PHASE软件构建单倍型并统计分析患者组及对照组单倍型频率是否存在差异。

In this experiment, we affirmed the best experiment reaction and detection condition in 5'-UTR,exon 1 and 3'-UTR of IGF-I gene and found four mutation Loci (23F/R,26 F/R,28 F/R,29 F/R) in New Yangzhou chickens, Xueshan chickens, White Leghorns chickens, respectively.

雪山鸡等位基因频率为:26F/R A:0.8200,B:0.1800;28F/R A:0.3819,B:0.6181;经基因型分布卡方检验,发现新扬州鸡上的两个多态位点处于哈代-温伯格平衡(P=0.929、P=0.966),雪山鸡不处于哈代-温伯格平衡(P=0.002、P=0.112),并发现多态位点存在品种分布差异。

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