多种免疫

Several antigens of pathogenic microorganisms, such as C subunit of tetanus toxin and the Brucella abortus ribosomal protein L7/L12, were successfully expressed in Lactococcus lactis.

破伤风毒素片段C、布氏杆菌L7／L12蛋白等多种病原微生物抗原已成功在乳酸乳球菌中表达，并已证明部分重组乳酸乳球菌作为黏膜免疫疫苗可以同时刺激局部黏膜免疫应答和系统免疫应答。

Safflor Yellow, extracted from Safflor, with proved pharmacological effect that can expand coronary artery, lower blood pressure, resist thrombus, endure anoxemia and restrain immunity, will have a good developing and applying future. Since 1970s, more than 200 kinds of components such as flavone, lignocelluloses and alkine, have been extracted from Safflor.

红花黄色素(Safflor Yellow，SY)是从红花中提取的有效成分，具有扩冠、降压、抗血栓、耐缺氧、免疫抑制等多种药理学功效，有良好的开发和应用前景。70年代以来对红花的化学成分进行了广泛的研究，已分离出了二百多种化学成分，其中主要有黄酮类、木脂素类、多炔类等。

A great deal of processes such as digestion, metabolism, detoxication, excretion and immunity are undertaken in liver.

目的：肝脏是一个具有多种生理机能的器官，并且有巨大的再生潜能和代偿能力，它参与机体的消化、代谢、解毒、排泄和免疫等多种过程，如何准确评估肝脏储备功能是目前肝病领域的重要课题之一。

Considering mothers' poor KAP status and low education level, health education on immunization should be implemented though interpersonal communication via assistant media, and educating emphases should be laid on some special-charactertics targets.

当地儿童母亲有关计划免疫的知信行水平较低，考虑其文化水平较低，应在当地大力开展以人际传播为主、结合多种大众媒介传播形式的计划免疫健康教育，尤其要针对某些特定人群进行重点干预。

Compared with classical cytotoxic T lymphocytes , NK cells are superior in the following aspects: NK cells are among the first cell types to be activated after intracellular pathogen stimuli, the activity of NK cells peaked between 1 to 3 days, retained during the first 7-10 days, and the T cells response emerged only after 7 days when the NK cell responses begin to decline; though comprising of only 10％-15％ of peripheral lymphocytes, NK cells mobilize most of the cell populations in a strong and high level response to different invasions, and act as key factors at early defense before a specific immune response could mount, while only certain clones were involved in T cell response; NK cells kill virus-infected or malignant transformed cells without pre-sensitization and without restriction by major histocompatibility antigen, which is usually a mechanism of immune escape to T cell recognition by virus-infected or tumor cells, thus NK cell in complementary with T cells play crucial roles in tumor and virus eradication.

NK细胞以其强大的细胞毒活性为特征，与细胞毒性T细胞相比，NK细胞具有如下特点：NK细胞虽然只占外周血淋巴细胞的10-15％，但是对刺激性因素产生应答的过程十分迅速，一次可以调动大多数细胞共同参与，而不是几个克隆的活化，免疫应答的强度高；病毒感染或恶性转化细胞的一个主要特征是细胞表达的MHCⅠ类分子下降或消失，并借助这一机制逃避特异性T细胞应答的识别，NK细胞介导的杀伤活性无需抗原刺激，不受MHCⅠ分子表达的限制，从而与T细胞应答互为补充发挥免疫防御的功能；NK细胞的免疫活性可以被多种细胞因子上调，其中IFNα，IL-2，IL-12，IL-15和IL-18具备更强的作用；NK细胞具有强大的细胞因子分泌功能，对于启动T细胞特异性应答必不可少。

Be a kind of big member of glycoproteins, it is still a kind of immunogen, and it can be divided into various serotypes according to the immunogen of its heavy chain constant region.

作为一种大分子糖蛋白，Ig 还是一种强的免疫原，并可根据其重链恒定区的免疫原性差异将其分为多种血清型。

The present invention relates to immunogenic compositions for intradermal delivery of an antigenic or immunogenic agent in combination with one or more excipients.

本发明涉及免疫原性组合物，其用于皮内输送与一种或多种赋形剂相组合的抗原性或免疫原性试剂。

In a very long incubation period, although no infection symptoms, appearance as an ordinary person, but the body's immune system by HIV continues to damage to the immune system can no longer maintain the minimum defense capability, a variety of normal People will not cause the disease so that patients will be pathogenic microorganisms in the conditions of the infection, caused brain, lungs, gastrointestinal tract and other parts of the disease and symptoms.

在很长的潜伏期中，感染者虽然没有自觉症状，外表一如常人，但全身免疫系统仍在继续受到艾滋病病毒的破坏，到免疫系统功能再也不能维持最低的防御能力时，多种对正常人不会引起疾病的病原微生物便会使患者发生条件性感染，引起脑、肺、胃肠道和其他部位的病变及症状。

As an ideal prime immunization vaccine,the DNA vaccine has the advantages of high purity,continuous expression of antigens with low dose, repeatable immunization and inducement of memory CTL with high titer.Similarly, recombinant virus can not only highly express the target antigen,simulate the inducement process of virus infection on body immunity,and induce various cytokines,but also be beneficial to the interaction of high-affinity antibodies with T cell receptors,and the generation of Th1 reaction and CTL reaction.

DNA疫苗抗原纯度高，持续表达低剂量的抗原，可多次重复免疫以及诱导高效价记忆性细胞毒性T淋巴细胞反应，是理想的用于初次免疫的疫苗；重组病毒能高效表达目的抗原，模拟病毒感染诱导机体免疫的天然过程，能诱发多种细胞因子，而且有利于高亲和性抗体和T细胞受体的选择，可以有效地产生Th1型和CTL反应。

As to the crabs'immunological research, the immune mechanism of crabs was still unclear, but it was commonly believed that immune of crabs was mainly non-special defense, in the process of which circulating haemocytes, phanoloxidase system, lysozyme, SOD in the serum played an important role.

尽管甲壳动物的血淋巴液内不存在免疫球蛋白，但是具有非特异性免疫的性质，适当的诱导可提高血细胞的吞噬能力及多种体液免疫因子的数量和活性。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。