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Review articles only; calretinin; fovea centralis; macula lutea; ora serrata; photoreceptors; rods; cones; optic tract; optic nerve; visual cortex; color vision; photoreception; opsin; rhodopsin; guanine nucleotide-binding protein; G protein-coupled receptors; ion channels (cyclic GMP-gated); guanylate cyclase; cyclic GMP; dark adaptation; visual pigments; polyenes; 11-cis-retinal; vitamin A; chromophores; arrestin; recoverin; phosducin; transducin; bipolar cells; retinal ganglion cells; retinal progenitor cells; amacrine cells; Mueller cells; light; retinogenesis; ommatidia; optic vesicles; retinitis pigmentosa; blindness; macular degeneration; blind spot; Mach bands; electroretinograms; binocular vision; visual acuity; vision; retina

唯一综述;钙网膜蛋白;中央凹;黄斑;锯齿缘;光感受器;杆状细胞;圆锥细胞;视束;视神经;直观皮层;色视觉;光感受;视蛋白;视紫质;鸟苷酸-结合蛋白;G蛋白-电偶受体;离子通道;鸟苷酸环化酶;环鸟苷酸;暗适应;视色素;多烯;11 - cis -视网膜;抗干眼醇;发色团;抑制蛋白;恢复蛋白;phosducin;转导蛋白;双极细胞;视网膜神经节细胞;视网膜祖细胞;无长突细胞;米勒细胞;光;retinogenesis;小眼;视泡;色素性视网膜炎;盲的黄斑变性;盲点;马赫带;视网膜电流图;双目视觉

4DRG was co-culture with sciatic nerve segment in 10鸖 DMEM;the axons were longer and surround the sciatic nerve segment which was regard as anew evidence for chemotropism.

结果:(1)在无血清条件下单独培养的DRG,背根神经节的轴突数目众多,外形纤细弯曲,不成束,并且施万细胞和成纤维细胞稀少,所以可以排除两者对轴突生长的影响,为观察来源于变性坐骨神经段的可溶性因子对轴突生长的作用提供了有利条件;(2)在无血清条件下DRG和变性坐骨神经段联合培养,①先单独培养DRG,4天后待神经元轴突长出,再与坐骨神经段联合培养,观察到神经元的轴突数目减少,外形挺直,部分轴突之间相互粘附成束;②变性坐骨神经段和DRG同时联合培养,神经元的轴突数目明显减少,外形粗壮,轴突之间相互粘附成束;(3)有血清条件下单独培养DRG,轴突数目较多,外形挺直,长短不一,部分神经元的轴突之间相互粘附,施万细胞和成纤维细胞数目众多,观察到的轴突生长情况受到施万细胞和成纤维细胞的直接或者间接的影响。

Results:(1)Among 40 rats, 36 rats were successfully established and the rate of success is 90 percent;(2)All the successfully established models demonstrated polydipsia, polyuria and the body weight was not increased. 6 rats suffered cataract after 3 months, and 4 rats died in 6 months;(3)There was an approximately 61% loss of retinal ganglion cells in the central retina and the thickness of retina thinner under microscope ( P 0.01 ).(4) Electroscope changes include the thinner of retina, disorganization of the membranous disc of the rod cells and the thickness of basal membrane of vessal.(5)In normal group, 1 month dibetes mellitus and 1 month treatmen group, there was no expression of ERK1/ERK2 on the retina tissues. In 3 month diabetes mellitus group, the expression of ERK1/ERK2 was positive.

结果:①40只建模大鼠中36只建模成功,建模成功率为90%;②建模成功的大鼠都表现出多饮、多尿、消瘦、体重不增的表现,有6只大鼠在3个月后出现白内障,有4只大鼠在喂养接近至6个月时死亡;③HE染色光镜下6个月大鼠后极部视网膜节细胞层细胞数明显减少,减少约61%(P.01),后极部视网膜明显变薄(P.01);④电镜观察,视网膜变薄,视杆细胞膜盘紊乱,血管基底膜增厚等表现;⑤正常组、糖尿病组和治疗组1个月大鼠视网膜中未见ERK1/ERK2的表达,糖尿病组视网膜组织中3个月时可见少量表达,ERK1/ERK2表达部位为神经节细胞层和内核层;6个月时表达强阳性,部位表达不仅见于内核层、神经节细胞层,色素上皮层也见表达。

Methods: NGF was prepared from mouse submaxillary glands by the way of elution with CM 52 column. The molecular weight and purification of NGF were detected by SDS-PAGE polyacrylamide gel electrophoresis.

以小鼠领下腺为原料,採用CM52多次洗脱的力法分离神经生长因子,SDS-PAGE电泳检测NGF的分子品质和纯度,採用鸡胚背根神经节培养方法检测NGF的生物活性。

The epineurial vessels run along the nerves length and gave off branches, distributing along nerve bundle, to enter into endoneurium. The endoneurium contained only capillaries. Arteriolovenular anastomoses were few in trigeminal nerve root. The distribution of microvessels in trigeminal nerve root was uneven. The number of microvessels in the medial portion was less than that of the distant.

神经外膜血管沿神经根径向走行,沿途再发侧支斜行或横行入神经束之间,顺神经根束分布,并发侧支进入神经内膜;半月结内微血管围绕神经节细胞分布;三叉神经根内的微血管配布不均,其近侧端微血管数量较少,远侧端微血管数量较多。

Results: the location, shape and number of the sympathetic ganglia were quite variable, and there was 1 to 6 in number unilaterally. Lumbar sympathetic trunk divided into 2-3 branches at the distal part were found in 12 sides. Lumbar arteries were all located under the lumbar sympathetic trunk and the lumbar veins, consisting (68.42+4.35)% situated superficially to the trunk, mainly in L4 arid L5 veins. Genitofemoral nerve pierced psoas muscle at the level of L2-L4 or its intervertebral disc (0.83±0.48) cm away from the medial edge of psoas muscle.

结果:腰交感神经节数目及位置变异较大,每侧1~6个不等;腰交感干可分裂为2~5支,分裂处多在干的下端,本组共发现12侧发生分裂;腰动脉均位于神经干的深面,腰静脉位于腰交感干浅面者占(68.42±4.35)%,以腰4、5静脉多见;生殖股神经穿出腰大肌平面多数与第2~4腰椎或椎间盘对齐,穿出点距腰大肌内侧缘(0.81±0.48)cm。

The anatomical localizations indicate that Al receptor and Dl receptor coexist in strionigro-strioentopeduncular neurons, and A2a receptor and D2 receptor coexist in striopallidals neurons. The heteromeric complexes of Al/D1、A2a/D2 receptor provided the molecular basis for the functional interactions of Al/Di and A2a/D2 receptor.

腺苷A1受体和多巴胺D1受体以及腺苷A2a受体和多巴胺D2受体分别共存於基底神经节中纹状体向黑质和脚内核投射的神经元以及纹状体向苍白球投射的神经元内。A1/D1、A2a/D2受体形成受体异聚复合体构成了受体一受体之间相互作用的分子基础。

Some sensory neres from the L2 and L5 ertebral bodies enter the paraertebral sympathetic trunks and reach the DRGs at multisegmental leels.

L2和L5的感觉神经纤维分别来自T11-L3和T13-L6的背根神经节。L2和L5椎体的一些感觉神经进入脊柱旁的交感神经干,最终到达多节段的背根神经节。

NGF positive immunoreactive cells were observed in the airway epithelia of control group. The positive reactivity are located at cell plasm. The NGF positive immunoreactive cells are round or polygonal shape and throughout the whole C〓~T〓 spinal ganglion of control group.

对照组豚鼠气道上皮内可见到含有NGF免疫反应阳性颗粒的上皮细胞,阳性反应物位于胞浆,呈棕褐色。C〓~T〓段脊神经节内,NGF免疫反应阳性细胞遍布整个神经节,多呈大圆形或多角形。

The rat L5/6 interertebral disc is multi-segmentally innerated from the L1-L6 dorsal root ganglions. Substance P and the neurokinin-1 receptor contribute to inflammatory pain transmission.

大鼠L5/6椎间盘受L1-L6背根神经节多节段神经支配的。P物质和神经激肽-1受体对感染性疼痛的传导起重要作用。

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