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Abstract] objective to analyse kawasaki disease' s clinical characteristic to improve the cognition and cure kawasaki disease.methods 52 kawasaki disease's clinical data from 1996 to 2005 in our hospital were reviewed.results in the 52 examples,34 were males,18 were females,the proportion was 1.89∶1.patients in 1~5 years old,took up 68.35%.symptom was pyrexia for over 5 days,antibiotic cure was useless.in the whole 52 examples,50 were exanthem,44 were eye conjunctiva congestion,50 lip bleeding with evaporation and dehiscence,46 myrica tongue,44 apyetous lympha denectasis in the neck area of the body,42 hand and foot-tip stiff swell,48 membrane peeling from hand foot-tip and the skin around anus after two weeks,12 cadiovascular expansion.

分析川崎病的临床特征以提高对川崎病的认识及治疗。方法回顾性分析1996~2005年我院收治符合川崎病标准的52例川崎病临床资料。结果 52例川崎病患儿中男34例、女18例,男女比例为1.89∶1。患儿年龄多在1~5岁,大约占68.35%。症状均为发热5天以上,抗生素治疗无效,其中皮疹50例,眼结膜充血44例,口唇干裂出血50例,杨梅舌46例,颈部非化脓性淋巴结肿大44例,手足末梢硬肿42例,2周后手足末梢及肛周皮肤膜状脱屑48例,冠状动脉扩张12例。

Results A total of 9 patients were found have N3 disease on mediastinosopy, with cancer-cell- positive lymph nodes in the contralateral mediastinum in 6 and 3 in the right scalene.

统计学分析显示,肺腺癌组的N3发生率高于非腺癌组(P〈0.05),血清CEA水平升高组的N3发生率高于正常组(P〈0.05),同侧纵隔淋巴结多站转移组的N3发生率高于同侧单站转移组(P〈0.05)。

The mean ADC value of lymphomatous, metastatic and benign lymph nodes was (0.874±0.17)×10~(-3)mm~2/s,(0.98±0.09)×10~(-3)mm~2/s and (1.20±0.10)×10~(-3)mm~2/s. There was statistically different between benign lymph nodes and other groups (P=0.00). When an ADC value of 1.085×10~(-3)mm~2/s was used as a threshold value for differentiating malignant from benign lymph nodes, the best results were obtained with an sensitivity of 87.8% and specificity of 91.3%. 16 of 18 cases (88.9%) were accurately staged in accordance with clinical staging. For 24 patients after chemotheraphy or radiotheraphy, 4 cases were complete remission and WB-DWI was negative. WB-DWI was positive in 14 of 17 cases with recurrent or remnant tumor. For 3 patients with suspected partial remission, WB-DWI indicated necrosis in 2 cases and inactive in 1 case. Repeated WB-DWI examination was performed in 13 cases, tumors were eradicated in 6 cases, improved in 4, expanded in 2. A new colon carcinoma besides its primary lesion was found in 1 case. The results of WB-DWI were all concordant with other clinical tests.

以ADC值1.085×10~(-3)mm~2/s作为诊断恶性淋巴结病变的临界值,敏感性及特异性分别为87.8%和91.3%。88.9%(16/18)患者WB-DWI检查后分期与临床分期一致。24例淋巴瘤患者放化疗后行WB-DWI检查,4例临床疗效为完全缓解,WB-DWI检查均为阴性,17例临床确认有肿瘤复发及明显残留,WB-DWI显示为阳性的14例,另外3例常规影像评价为部分缓解的患者,WB-DWI检查提示2例病灶以坏死液化为主,1例病灶无明显活性。13例淋巴瘤患者行多次WB-DWI检查,发现6例治疗后病灶消失,4例缓解,1例原发病灶缓解,新出现结肠癌,2例淋巴瘤进展,皆与临床相符。

Nodules can usually be seen to involve the pleural surfaces and fissures, but lack the subpleural predominance often seen in patients with a perilymphatic distribution.

但淋巴管周围结节型的在胸膜下分布的多(淋巴结周围型的结节数量很多分布于胸膜下———译者注

Some HIV-infected persons into the body in about 2 ~ 4 weeks, the emergence of HIV viremia and immune system damage produced by acute symptoms such as fever, sweating, pharyngodynia, diarrhea, rash and swollen lymph nodes and so on, the majority of infected clinical symptoms were mild, continuous 1 ~ 3 weeks after the remission, but these symptoms are often mistaken for the common cold or some of the symptoms of common diseases, it will not cause people's attention, when infected and healthy looking from the outside there is not much difference.

有些感染者在艾滋病病毒进入体内约2~4周时,出现艾滋病病毒血症和免疫系统急性损伤所产生的症状,如发热、盗汗、咽痛、腹泻、皮疹和淋巴结肿大等,大多数感染者临床症状轻微,持续1~3周后缓解,但是这些症状往往被误认为是普通感冒或一些常见病的症状,也不会引起人们的注意,这时感染者从外表上看和正常人没有多大区别。

Emphasis is put on cytological diagnosis of frequently seen oromaxillofacial tissues, and tumorlike lesions in cervical lymph nodes and their benign and malignant tumors, and the clinical and histopathology of the diseases mentioned are precisely and briefly described.

全书所论述的头颈部各种良性、恶性病变多达100 余种,重点突出常见的口腔颌面部组织、颈部淋巴结以及各种头颈部瘤样病变及其良性、恶性肿瘤的临床细胞学诊断,并对所述疾病的临床及组织病理学进行了精简表述。

Multivariate analysis considering caveolin-1 immunoreactivity in addition to the established prognostic parameters such as pT stage, pN in these patients confirmed that caveolin-1 is an independent functional predictor of poor survival. We further revealed that up-regulated caveolin-1 in CL cells is necessary for mediating filopodia formation which may enhance the invasive ability of lung adenocarcinoma cells.

利用多变数分析的方法分析Caveolin-1及其他已知会影响预后的变数,例如肿瘤大小及淋巴结转移状况等,证实Caveolin-1的确是影响预后的独立变数,最后我们发现Caveolin-1会引起肺腺癌细胞产生伪足,这可能是Caveolin-1造成癌细胞侵袭性增加的原因。

It is now well-accepted that there are relations between LNM and prognosis of PTC which is concluded from several long term follow-up investigations.

越来越多的长期随访资料证明,颈部淋巴结转移与患者的长期生存率、无瘤生存等预后指标有关,是影响PTC患者预后的一个重要因素。

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