多步的

So for me, this project shows kind of how far we can go from some of those sort of small things that I was working on at the beginning of my career. That by focusing on the needs of humans and by using prototypes to move ideas along quickly, by getting the process out of the hands of designers, and by getting the active participation of the community, we can tackle bigger and more interesting questions. And just like Brunel, by focusing on systems, we can have a bigger impact. So that's one thing that we've been working on.

对我而言，这个专案显示我们能延伸出多大的影响，就从这小小的一步开始，也就是那些我曾做过的事，在我设计生涯开始的时候，藉由关注人类的需求与使用模范原型来快速地启动创意，让进程跳脱设计师之手，让社区主动参与，我们就能应付更大、更有趣的问题，就像Brunel，只要专注於系统上，我们就能创造出更大的影响力，这就是我们正努力不懈的事。

The speciality to let several coefficients of S-M algorithm are analyzed;(2) We first propose the nonlinear and adaptive prediction model based on several closest neighbors and extend the method to multistep prediction;(3) We first exploit Empirical Mode Decomposition technology to predict hopping frequency codes, it is namely that a complex time series is decomposed as several Intrinsic Mode Functions easy to prediction, then predict these IMF respectively, at last reconstruct estimated values of the time series;(4) We exploit the above prediction model validate effect while there are omitted data in observed time series and propose the corresponding resolve.

1具体分析了S-M算法中几个参数设置的特点；(2)首次提出了基于邻近点的非线性自适应预测模型，同时将这种算法推广到多步预测；(3)首次采用经验模态分解技术预测跳频码，即将一个复杂难以预测的时间序列分解为几个相对容易预测的本征函数，然后分别预测这些本征函数，最后重构出时间序列的估计值；(4)应用基于邻近点的非线性自适应预测模型验证了观测时间序列存在数据缺损时的预测效果，并提出了相应的解决办法。

Based on the single-axis air-bearing test bed, three experiment schemes are creatively designed for investigating the behaviors of rigid-flexible coupling dynamics:(1) experiment scheme for structural dynamics problem under a non-inertial frame,(2) experiment scheme for rigid-flexible coupling dynamics with unknown large overall motions,(3) experiment scheme for modal analysis of a typical rigid-flexible coupling system.

为了能更深入地揭示刚柔耦合动力学特性与验证本文提出的一次近似模型的正确性，最后重点介绍了我们在单轴气浮台动力学仿真实验平台基础上，经过多次探索和总结，创造性地设计的三套刚柔耦合动力学实验方案：(1)非惯性系下结构动力学问题的实验研究方案，(2)大范围运动为自由的刚柔耦合动力学问题的实验研究方案，(3)刚柔耦合系统模态分析实验方案。这三套方案从实验的角度来讲是可行的，这为下一步的实验工作打下了基础。

Beijing Jinsoar Armarium Co., Ltd. is a is a manufacturer based on research, development, production and sale of rehabilitation physiotherapy equipment. The company is in possession of professionals with responsibilities for manufacture and development and a marketing team with super quality and full of experience. It has created a stable marketing channel all over the country.CM Series PC-IF electrotherapy instrument, which is a patent to this company, is the use of modern computer technology to make the clinical experience into prescription, forming a unique multi-step procedures for current therapies, acting upon the human body, so that users have pushing, grabbing, knocking, kneading, rolling, fluttering and other many varieties of manual massage feelings, is useful to diminish inflammation, to ease pain, to simulate the circulation of blood and to improve blood circulation, playing good treatment effects on soft tissue injury, neuromuscular disease and osteoarthropathy. It has already been used widely by many hospitals and spas in and ouf of the country.

北京洁翔医疗设备有限公司是国内以研制、开发、生产和销售康复理疗仪器为主的厂家，不仅拥有产品研发、生产的专业技术人员，同时更有一支高素质、经验丰富的专业销售队伍，并在全国建立了稳定的销售渠道，其生产的CM系列电脑中频治疗仪是本公司的专利产品，它把临床经验编制成处方，形成独特的多步程序处方电流疗法并作用于人体，使患者产生推、拿、敲、揉、滚动、震颤等多种手法按摩的感觉，起到消炎、镇痛、活血化瘀和改善血液循环的作用，对软组织损伤、神经肌肉和骨关节病等常见病具有良好的治疗效果，目前已为国内外医院、疗养院所普遍采用。

Some approved aneugens Trip terygiuwlIypogaucum (evelHutch, colchicine, thiabendazole, a tropine sulfate,d-ubocurarine was added into the reactive system respectively and the changes of their absorption values were taken down during different periods under the conditions of 37 0C and 350nm .

本研究通过多步聚合和解聚合反应从猪脑中分离纯化微管蛋白，建立微管蛋白的体外聚合和解聚合反应平衡体系，并将已证实的非整倍体诱发剂（昆明山海棠根部水抽提物、2-（4′-噻唑）苯丙咪唑、硫酸阿托品、d-筒箭毒碱）分别加入此反应平衡体系中，于37℃、350nm条件下，记录此体系不同时期的吸光值变化，与阳性对照物和溶剂对照处理平衡体系后的吸光值在相同时间点作比较，以此评估这几类非整倍体诱发剂对离体条件下的微管蛋白聚合的影响，寻求这几类非整倍体诱发剂是否可通过抑制微管蛋白聚合作用途径而诱发非整倍体。

Started from D-tyrosine, we obtained the tetramic acid 96 using Jouin reaction. The assembly of the second fragment 109 was stared from 1,4-butandiol,using asymmetric alkylation reaction developed by Oppolzer as a key step. Coupling of the tetramic acid 96 with 109 provided the key intermediate 110 according to Yoshii\'s procedure. After remove protective group and Sharpless epoxidation, we obtained the key intermediate 113. Its macrocyclization to form the final product is in progress.

本论文的第二章主要对Macrocidin A开展了合成工作，我们从D构型的酪氨酸出发，经过官能团转换；利用Jouin反应生成Tetramic acid 96，另外一个片断从1，4-丁二醇开始经过多步反应生成碘化物104，利用Oppolzer发展的手性樟脑磺酰胺为辅基参与的不对称烷基化反应，引入手性甲基，生成关键中间体109，接着通过Yoshii发展的方法连接96和109生成110，经过Sharpless不对称环氧化反应建立环氧化合物，然后脱去保护基得到关环前体113，分子内的Mitsunobu反应进行关大环反应正在进行之中。

A series of antimony mercaptide compounds which formula are Sb 〓 and Sb S (CH〓〓COOR 〓(R represents an alkyl or aryl, aralkyl, n=0～2) have been synthesized. A new synthetic method has been invented to solve the defect of abroad patent method which has complex technological conditions and singleness intermediate compounds. A new catalyst QL-1 and preactivated antimony trioxide and other means have been used to avoid neutralizing, washing, separating and other procedures of intermediate and simplifing process flow at the same time. According to this new technique, a series of antimony mercaptides and their intermediate products have been synthesized with high yield.

合成了结构为SbS(CH〓〓COOR〓及Sb〓（R为烃基或芳烷基，n=0～2）的一系列硫醇锑化合物，针对国外专利报道的合成工艺存在着工艺条件苛刻，同时需多步完成，操作复杂，而且中间体品种单一的缺陷，发明了一种一步法合成硫醇锑化合物的新工艺，采用QL-1催化剂，且将三氧化二锑预先活化，变固—液相反应为液—液相反应，同时可免除中间体的中和、洗涤、分离等工序，工艺流程简化，产品收率高，且能制得系列硫醇锑产品。

Then we completed the first total synthesis of-Plakoridine A using Eschenmoser couping reaction as akey step. During the synthesis we found the choice of protecting groups and the configuration of the chiralcenter of the substrate play an important role to the key Eschenmoser reaction,so we think our successwould be of guide for synthesizing other polysubstituted pyrrolidines or piperidines.

在论文的第一章中，我们先以易得的对羟基苯乙酸乙酯为原料经多步反应制得了所需的β氨基酸酯，然后利用立体选择性的Aldol缩合反应和内酰胺化反应制得了Plakoridine Alactam，随后，以Eshenmoser缩合反应为关键步骤完成了生物碱-Plakoridine A的首次不对称全合成。

Firstly, a mathematic model was constructed to deal with fault isolation. This model mainly considered the associations among fault sources and available testing of hierarchical system, the affiliation of faults with replaceable units in different levels, the prior probability of fault sources and the available testing costs. Secondly, a quasi multi-step look-ahead search algorithm was presented which employed the information gain as its heuristics. This algorithm could realize optimization of testing sequence in different isolation levels.

首先基于层次系统故障与测试之间的关联关系，以及故障与不同层级可更换单元的隶属关系，结合故障的先验概率与可用测试成本，构造了层次系统故障隔离问题的数学描述模型；然后以信息增益为启发策略，提出了一种准多步前向搜索算法，实现了不同隔离级的测试顺序优化。

His later crowning as Emperor Otto I (later called "the Great") in 962 would mark an important step, since from then on the Empire – and not the West-Frankish kingdom that was the other remainder of the Frankish kingdoms – would have the blessing of the pope.

他晚一些在962年的作为皇帝奥多一世的加冕被定位重要的一步，从此，帝国，——而不是在其它中的法兰克王国中的西法兰克王国——，得到了教皇的保佑。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。