多次结果的

A gas chromatographic method to determine the conversion of asymmetric hydrosilylation of acetophenone has been established.

建立了由气相色谱法测定苯乙酮不对称硅氢化反应转化率的定量方法，操作简便、迅速，重复性和精密度较好，多个样品各重复6次的变异系数均小于1％，且结果与1HNMR法测定结果一致。

Taking ADL Evaluation Scheme for Cerebral Palsied Children as main efficacy value,very marked statistic difference exists when two groups with or without Madopar were assessed on the third evaluation in our study,and it shows the effects of Madopar while its adverse events are mild ...

结果显示：以脑瘫儿童日常生活能力评价表作为疗效评价标准，用美多巴治疗组与不用美多巴治疗组在第3次评价时有极显著性的差异（P＜0.001）。

Results There was not specificity of clinical symptoms in liposarcoma of the orbit, the major clinical aspects were intraorbital occupied lesion and local hyperaemia,swell and pain which was similar to an acute inflammation. Four different subtypes of liposarcomas could be observed in orbit.In past literature,myxoid was the most common subtype（14 cases,70%）,secondly subtype was well differentiated（3 case）,round cell and pleomorphic subtype were rare（each 1 case）.This case was well differentiated mixed component of round and pleomorphic lipoblasts.

结果：脂肪肉瘤临床表现为眶内占位和貌似急性炎症的局部红、肿、痛，无特征性的症状；病理分型4型，文献中报道以粘液样型最多见（14例，占70%）；次为分化良好型，3例；圆形细胞为主型及多型性各1例；分型不详2例；本例为分化良好型为主伴有圆形脂母细胞及多型性脂母细胞成分。

Several anti-tumor cell lines and carbonic anhydrase Ⅱ model were established. More than 10000 compounds and extracts from plants were screened using these models and about 10 compounds showed strong inhibitory activities. Two species of plants Inula helianthus-aquatica and Saussurea deltoidea were chosen to investigate chemical and bioactivity constituents based on the results of screening of extracts and fractions. 58 compounds were isolated and identified from these two plants, 6 compounds were found to be new and 14 compounds showed anti-tumor activities. We also studied the anti-tumor mechanism of the compound bigelovin isolated from Inula helianthus-aquatica. Bigelovin was found with apoptotic activity against cell line U266 by lowering the amount of important transcription factor E2F-1 which inhibits the cell cycle at G0/G1 stage. Docking study on 7 natural new phenolic inhibitors of CA Ⅱ and 3D-QSAR study on 61 sulfonamide inhibitors of CA Ⅱwere also investigated. The calculated results were in good correlation with experimental results.

基于以上两种重要疾病和研究组方向，本论文工作开展了多个肿瘤细胞株和碳酸酐酶Ⅱ靶标模型的建立和筛选工作，累计筛选1万多个/次样品，发现10余个活性较强化合物；从粗提取物筛选结果中选取两种抗肿瘤活性强的菊科植物水朝阳旋覆花(Inula helianthus-aquatica)和三角叶凤毛菊进行了系统化学和活性成分研究，分离鉴定了58个化合物，发现6个新化合物和14个抗肿瘤活性化合物；通过合作对水朝阳旋覆花中活性较强的bigelovin进行了抗肿瘤作用机制研究，发现它可能是通过降低G2期重要的转录因子E2F-1，致使细胞周期阻滞在G0/G1期，引起多发性骨髓瘤U266细胞凋亡；开展了7个新的天然酚类CAⅡ抑制剂的对接研究和61个合成的系列磺酰胺类CAⅡ抑制剂的3D-QSAR分析，结果表明计算与实验一致。

The results show that the multi-stage and multicycle of tectonic movement in China continent result in the superimposed basin pattern which has many types of basin and mountain coupling systems with multi-stages.

结果表明，由于中国大陆构造运动的多期次和多旋回性形成的叠合盆地格局，不但发育有多种类型的盆山耦合关系，而且造成盆山耦合的多阶段性。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

Martin Petrov had two good opportunities and shot wide both times, Emile Mpenza miscued after getting himself into a good position and staying onside, then Elano wasted the best chance of all by shooting when the unmarked Stephen Ireland was waiting for a pass in a much better position.

马丁·彼德罗夫有两次很好的射门机会都打高了；埃米尔·姆蓬扎有一次位置很好，但是他误以为自己越位了，结果站在原地没动；之后埃拉诺的射门浪费了最好的一次机会，那个球如果传给他旁边无人盯防的史蒂芬·艾尔兰就好了，后者的位置比他要好得多。

The main findings were as follows: 1.the studied on the research area soil fertility factor and the quality of material had carried on the traditional statistical analysis,compared with the nation second general detailed soil surveys nutrient grading standards result indicated that the sampling area main fertility factor density concentrated much in medium and lacks level;The AP content was lower,the type area soil was more barren.

主要研究结果如下： 1。对研究样区土壤肥力因素和质地进行了传统统计分析，并与全国第二次土壤普查的养分分级标准比较结果表明，采样区主要肥力因素量值多集中在中等及较缺水平；速效磷含量更低，样区土壤较为贫瘠。

The main results are:In logic system ,G,tautologies can not be get by using upgrade algorithm to non tautologies within finite many times;In logic system G n,tautologies can be get by using upgrade algorithm to an arbitrary formula of F at most n times; Congruence partitions about on F have been given in logi...

主要结果是：在逻辑系统 G，G中，重言式不可能由对非重言式进行有限次升级算法得到；在逻辑系统 Gn 中，对任一公式最多进行 n次升级算法即可得到重言式；利用可达广义重言式概念和α-矛盾式概念分别在 G，G，Gn 中给出了 F的一个关于同余的分划。

The main results are:In logic system r,G r, tautologies can not be get by using upgrade algorithm to non tautologies within finite many times; In logic system S n , tautologies can be get by using upgrade algorithm to an arbitrary formula of F at most n times; Congruence partitions about ...

主要结果是：在逻辑系统 Gr，Gr 中，重言式不可能由对非重言式进行有限次升级算法得到；在逻辑系统Sn 中，对任一公式最多进行n次升级算法即可得到重言式；利用可达广义重言式概念和α矛盾式概念分别在 Gr，Gr，Sn 中给出了F的一个关于同余的分划。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失