多核细胞

On the morphological differentiation,by inducing of fetal calf serum,it wasshown that the cytotrophoblast cells underwent aggregation first,and the adjacentcytoplasm membranes became tightly contacted through desomosomes andcytoskeleton.Then the adjacent cytoplasm membranes disintegrated fragmentallyto form fusion pore-like structure.Finally the multinuclear cells formed and inwhich the intercellular desmosomes disappeared.Immunocytochemical stainingfurther demonstrated that the formation of syncytium was through cell membranefusion rather than the amitosis process.

细胞形态分化的研究结果表明：早孕胎盘来源的细胞滋养层细胞在血清诱导下，首先发生聚集，并通过桥粒和细胞骨架使相邻的细胞膜紧密接触；之后细胞膜发生片段断裂，形成融合孔样结构；细胞间桥粒消失，最终形成多核的合体细胞；免疫细胞化学分析进一步证实合体化是通过细胞膜融合而非无丝分裂（amitosis即细胞核分裂而细胞质不分裂）实现的。

After prolonged exposure to ANE, the accumulation of hyperploid cells, micronucleated or multinucleated cells were noted concomitantly with centrosome amplification.

另外，长时间的作用下多倍体，多核或微核细胞之有明显的增多，同时也发现常之中心体。

Results Ten categories of cytologic features found in the smear of osseous tumors were pleomorphic giant nuclear cell (91.3%), obvious nucleoli(69.5%),mononuclear gaint cell(76%), multinuclear gaint cell(65.2%),karyokinesis(36.9%), hemorrhage and necrosis(93.4%).

结果：观察到骨肿瘤中有关 10种细胞学改变：骨肉瘤涂片中，多形性大核细胞（91.3%），核仁明显（69.5%），单核瘤巨细胞（76%），多核瘤巨细胞（65.2%），核分裂象（36.9%），出血、坏死（93.4%）。

Myoblast that isabundent and easy to get can fuse with the local myoblast to formpolynuclemyoblast and live in myofiber after transplantation.

成肌细胞数量丰富，易于获取，可以通过注射进行大规模细胞移植，可与宿主的肌肉细胞融合形成多核肌细胞，并可以在肌纤维中存活。

Treated by higher concentration of EMS,some cells appeared micronuclei,abnormal nucleus,poly nuclei,broken nucleus,and nucleolus losing.

较高浓度EMS处理的PLB细胞中出现微核、畸形核、多核、核破裂和核仁丢失等现象。

FUNGI Fungi are almost entirely multicellular, heterotrophic (deriving their energy from another organism, whether alive or dead), and usually having some cells with two nuclei multinucleate, as opposed to the more common one, or uninucleate per cell.

FUNGI Fungi是几乎完全地多细胞性，异养(获得他们的能量从另一个有机体，是否活或死)和通常有与二个中坚力量的有些细胞多核，与更加共同一个相对或者单核每个细胞。

mitochondrial dnais the only inheritant substance except for the nuclear dna in a euˉkaryon cell,which is related to the oxidative phosphorylation of a cell.mitochondrial dna is the important target of carcinogens and is vulnerable because of its structure and function.the mutation of mtdna could reduce the nomal respitation and release large quantities of ros,whichincrease the danger of cancer happening.so,mtdna has been thought to be involved in carcinogenesis and recently more and more studies in this aspect have comeout.in this paˉper,we review the researches for relationship among mtdna mutation and tumors in digestion system,woman system,head and neck,urinary systemand blood system.

线粒体dna（mitochondrial dna，mt dna）是真核细胞中唯一存在的独立于核dna之外的遗传物质，与细胞的氧化磷酸化功能密切相关。mtdna自身的结构和功能特点决定了它是致癌物作用的重要靶点，易受致癌因素的损伤而发生突变。mtdna的突变可削弱正常的呼吸功能，释放高水平的活性氧，进而增加肿瘤发生的危险性，所以mtdna被认为与肿瘤发生有密切关系。近年来，这方面的研究越来越多，本文现就mtdna突变与消化系统肿瘤、妇科肿瘤、头颈部肿瘤、泌尿系统肿瘤等实体瘤以及血液系统恶性肿瘤之间的关系作一简单的综述。

Results Microscopically, AM was characterized by hypercellularity, high karyoplasma ratio, prominent macronucleoli, strange heterokaryocyte and tiny focal necrosis. Of 11 cases, recurrence was noted in three, and one transformed into anaplastic meningioma and died 1 year after reoperation.

结果 AM光镜下瘤细胞密度增大，核浆比例增高，核仁明显，多伴有奇异核细胞出现和微小坏死灶。11例AM病人中，3例复发，1例复发后转变为间变性脑膜瘤，再次手术后1年死亡。

The cell cycle and apoptosis and the expression of P-pg, bcl-2, P53 in the MG63 and MG63/R cell lines were analyzed by flow cytometry. Results The resistance index of the MG63/R cells to cisplatin was 83.557±4.841. The cells also had resistance to doxorubicin, vincristin, methotrexate and cyclophosphamide. Disordered structure of the MG63/R cells was observed through microscopy. The cells appeared in triangle, polygon and polynucleation. The increase of granular endoplasmic reticulums and apophyses was observed through transmission electron microscopy. The proliferation ability of MG63/R increased significantly, with a low apoptosis index.

结果 经顺铂186d的诱导，建立了MG63/R，其对顺铂的耐药指数为83.557±4.841，对阿霉素、长春新碱、氨甲基蝶吟、环磷酰氨亦产生不同程度的交叉耐药；光镜观察可见MG63/R细胞排列不规则，形态呈三角形、多角形及多核现象；透射电镜显示MG63/R细胞表面突起增加，粗面内质网丰富；细胞周期分析显示细胞增殖能力明显增加而细胞凋亡明显降低；MG63/R细胞 P-pg、bcl-2阳性表达较MG63细胞明显增加，P53表达则明显降低。

Human hair keratin ; spinal cord injury ; rat ; tissue engineering ; tissue-engineered spinal cord ; connector ; morphology ; praxiology ; neuron ; axis-cylinder ; nerve fiber ; myelin sheath ; astrocyte ; oligodendrocyte ; microglia ; ependymal cell ; neural stem cells ; macrophage ; multinuclear giant cell ; lysosomal enzyme ; ubiquitin system ; suppression subtractive hybridization ; gene express ; CytohromeoxidaseⅢ; amino acid transporter system A2（Ata2）; Peroxiredoxins 5（prd 5）; cysteine proteinase inhibitor cystatin c

国家自然科学基金；广东省自然科学基金人发角蛋白；脊髓损伤；大鼠；组织工程学；组织工程化脊髓；桥接物；形态学；行为学；神经元；轴突；神经纤维；髓鞘；星形胶质细胞；少突胶质细胞；小胶质细胞；室管膜细胞；神经干细胞；巨噬细胞；多核巨细胞；溶酶体酶；泛素肽酶系；抑制消减杂交；基因表达；细胞色素氧化酶Ⅲ；氨基酸转运蛋白系统A2；抗过氧化物蛋白5；半胱氨酸蛋白酶抑制剂

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷