多核细胞

The results of light microscopical studies showed many giant and multinucleate giant cells with even more than twenty nuclei in each cell. It was possible that the formation of multinucleate giant cells associated with repeated endomitosis in a single cell.

光学显微镜观察见K562/IL-2细胞中出现较多巨大细胞及多核巨细胞，细胞核数目可多达20余个，推测多核巨细胞的形成可能与细胞核反复分裂而胞质不能分裂有关。

More cleavage phases can be counted by FISH than G-band dyeing on the diagnosis of mosaicism kyrotype, even many intermediate stage cells can be analyzed by FISH procedure. Time was saved and more precise results can be found.

与常规染色体核型分析方法比较，FISH技术检测嵌合体核型能够观察到更多的分裂相，还可分析核膜完整染色体未分散的间期细胞，计数更多的细胞，为临床提供更准确的数据，且省时。

The relationship between the proterozoic Era and explosive evolution of the life on the Cambrian period was preliminary explored by an Ecological and Evolutionary approach in this paper.

距今38亿年前地球最早生命诞生以来，至元古代早期第一个真核细胞开始出现；从无性分裂或出芽繁殖的原核生物到有性繁殖的真核单细胞生物以及从单细胞的原生动物到真核多细胞的后生动物的进化，无疑是生命进化过程中非常重要的事件。

It was negative for co-culture of Vero cells with upper fluid of iris, ciliary body and retina which were blindly transfered to the third generation. No Cytopathological effects were observed, while the positive contrast group had CPE including such as ballooning degeneration, karyopyknosis ,multinucleated giant cell even cell necrosis.

Vero 细胞分别与虹膜、睫状体、视网膜组织上清液共培养，并盲传三代结果为阴性，未观察到细胞病理学改变，对照组有阳性表现，表现为Vero 细胞气球样变、核固缩、多核巨细胞甚至细胞悬浮死亡。

The main pathological findings include a desquamative interstitial pneumonia-like reaction with intra-alveolar macrophages and numerous large multinucleated histiocytes that ingested inflammatory cells were admixed with macrophages.

GIP主要病理表现有脱屑性间质性肺炎样反应，即在肺泡腔内有巨噬细胞和大量的多核巨细胞聚集，位于肺泡腔内的多核巨细胞内可见被吞噬的炎性细胞，是GIP的特点。

The proliferating cells were mainly distributed in the peri-chondrium and the peripheral zone of tracheal cartilage. The senescent chondrocytes were distributed in the central zone whereapoptotic morphological characteristics obviously appeared, such as pyknosis, karyorrhexis.

结果：软骨细胞呈现多种方式的无丝分裂像；气管软骨膜与软骨周围带多见细胞增生；气管软骨中央带多见衰老的软骨细胞，并见明显核固缩、核碎裂等细胞凋亡形态学特征。

Results: At the concentrations of 0.1, 1 and 10 μmol/L, berberine dose-dependently suppressed the formation of TRAP-positive multinucleated cells, the TRAP activity and the osteoclastic bone resorption. The strongest inhibitory effect was exhibited at the concentration of 10 μmol/L, with the inhibiting rate of 60.45%, 42.12% and 72.69% respectively.

结果：小檗碱在0.1~10μmol/L范围内，浓度依赖性地抑制TRAP阳性多核破骨细胞的形成和TRAP活性，减少破骨性骨吸收陷窝的面积；在10μmol/L浓度下，对破骨细胞的抑制作用最强，对TRAP阳性多核破骨细胞的形成和TRAP活性的抑制率分别达到了60.45%和42.12%，骨吸收陷窝面积减少72.69%。

Objetive:To investigate the histopathological features and detect the mutation of JAK2V617F in PV、ET and IMF;to analyze the effects of the stages of myelofibrosis and the mutation on the number of leucocyte in PV and ET patients;Methods: the morphological features of 69 patients who dignosed in the first time were studied by HGF and Gomori stains ; the mutation of JAK2V617F was detected in 38 blood or marrow samples of PV、ET and IMF patients by real-time PCR;the effects of the stages of myelofibrosis and the mutation on leucocytes were analyzed;Results: Different stages of reticulin were observed in 15 PV and 15 ET patiens'marrow sections,and the cytosis、the pleomorphism and the bone trabecula side location of megakaryocytes were observed in all PV、ET and IMF patients;the means of leucocyte in patients with and without JAK2V617F were 20.4×109/Land 11.4×109/L respectively;the P value was 0.367 as comparing the leucocytes among different stages of reticulin increasing.

目的：探讨PV、ET、IMF患者的骨髓病理特点并且检测JAK2V617F突变的发生率，分析骨髓中纤维增生程度以及JAK2V617F对PV、ET患者白细胞数的影响；方法：69例初诊患者的骨髓切片经HGF染色以及Gomori染色后进行形态学研究；并利用real-time PCR法测38例患者的骨髓或者外周血的JAK2V617F突变；分析骨髓切片中纤维组织增生程度以及JAK2突变对患者白细胞数的影响；结果：15例PV和15例ET患者的骨髓切片中可以观察到不同程度的纤维组织增生，所有PV、ET、IMF患者骨髓病理中可见到巨核细胞增多、巨核细胞多形性改变以及巨核细胞定位于骨小梁旁；12例PV、4例ET、4例IMF中检测到JAK2V617F；有突变和无突变患者发病时白细胞数均值分别为20.4×109/L和11.4×109/L，比较不同纤维增生程度的PV、ET患者的白细胞数均值，P值为0.367。

Biochemical indicator such as TG and SF were unregulated while 1 system or 2 system reduced in peripheral blood; Bone marrow hyperplasia showed active or active obviously. Complete morphological nucleated cells mature erythrocytes or platelet hemophagocytic cells were found in 100% marrow slides. Marrow hemophagocytic cells were quantified as 0.5 to 11 per micro liter Median 4.2 per micro liter. Phagocytes showed smaller size single nucleus on one side. Submitting as rings cell plasm showed gray or salmon pink and cell showed disorder fringes.

结果： 符合HPS者30例诊断为HPS早期21例；HPS早期有持续高热峰值≥38.5 ℃、发热期≥4天发病与感染相关；以病毒感染最多见，生化指标TG增高、SF增高；外周血细胞一系或二系减低；骨髓增生活跃或明显活跃，骨髓片（100%）找到吞噬了完整形态的有核细胞、成熟红细胞或血小板的噬血细胞骨髓噬血细胞0.5-11个/ul中位数4.2个/ul吞噬细胞体积偏小多为单个核核偏一侧，可呈印戒样，胞浆灰兰或淡红色，细胞边缘不整齐。

Complicated than procaryotes. These cells, exemplified by the yeast in Figure 4.1-3, have a membrane surrounding the cell which is similar in structure to the procaryote membrane.

真核细胞，具有真正的细胞核，其结构要比原核生物复杂的多，以图4.1-3中所示的酵母菌为例，和原核细胞一样真核细胞也具有一层细胞膜。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷