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Certain solid-state properties of the drug substance (e.g., polymorphic form or amorphism, solvation or hydration, various types of inclusion complexes, and particle size or surface area) may profoundly affect dissolution and bioavailability from solid dosage forms or suspension drug products.

一些原料药的固态特性(如:多晶型物或无晶型物,溶剂化作用或水合作用,各种包含物复合体,颗粒尺寸或表面面积),可能极大地影响着固态和悬浮态形式的制剂药品的分解的生物药效率。

The grain size of the film was about 30 nm when it was calcined at 500 oC for 10 hours.

采用多次旋涂的方法在多晶氧化铝衬底上制备出平均粒径从90 nm到400 nm、厚度达1 μm的致密薄膜。

All the complex series based on 4',4''-dicarboxy-1,6-diphenoxyhex- ane (C6-2COOH) and 4',4''-dicarboxy-1,10-diphenoxydecane (C10-2COOH) possessed higher melting and clearing points, usually showed soft crystal or crystalline smectic phases and crystal polymorphs except C10-2COOH/ p -PhBPy complex displaying also an enantiotropic nematic phase, while the complexes based on 4,4'-dicarboxy-α,ω-diphenoxy tetraethyleneglycol ether (C8O4-2COOH) with a longer flexible spacer exhibited monotropic fluidic smectic SmA and/or nematic phases.

研究表明,分别具有较短的6或10个亚甲基的烷烃间隔基的双苯甲酸衍生物4',4''-二羧酸-1,6-二酚氧基己烷(C6-2COOH)和4',4''-二羧酸-1,10-二酚氧基癸烷(C10-2COOH)的系列复合物具有较高的熔点和清亮点,一般都只出现结晶近晶相和多晶型转变现象。

The low rate of the electron transfering through the multicrystalline network of a nano-crystalline thin film, and the low efficicency of the dye absorbing the low energy photons are two limiting factors that influence the photoelectric conversion efficiency of the cells.

电子通过纳米晶薄膜多晶网络的低速率和染料分子对低能量光子的低吸收率是影响染料敏化太阳电池提高光电转换效率的两个主要原因。

The results showed:there were some differences in phase structure,composition and morphology for the films synthesized at different sulphurization temperatures and time;the films sulphurized at a temperature of 240 ℃ for 45 min were polycrystalline SnS films with orthorhombic structure.

当硫化温度为240 ℃、硫化时间为45 min时,所制得的薄膜为正交结构的SnS多晶薄膜,其均匀性、致密性以及对基片的附着力都较好,具有(111)方向优先生长,薄膜粒径在200~800 nm,且晶格常数与标样的数值吻合很好。

From the results of solid-phase crystallization method, we found that a-Ge is transformed into poly-Ge at 500 ℃ for 1 hour annealing and then the grain size saturates.

从固相结晶法的结果,我们发现在经过500 ℃ 1小时的退火处理后,非晶锗会转变成多晶锗且晶粒尺寸会达到饱和,不再随退火时间的增加而增加尺寸。

The microhardness of the nano-Ag is 0.9GPa which is about 2 times of that for coarse-grained polycrystalline metal silver.

大尺寸纳米银块体的室温显微硬度为0.9GPa,是多晶粗晶银的2倍,显示高硬度特征。

The crystalline defects of metallic substrate can promote the formation of multi-crystal thin films. In contrast, the films on the Si single crystal are basically amorphous; The hardness of films are mainly determined by N concentration. The highest hardnesses of Si〓N〓 and TiN films ware obtained at 1. 1 of N/Si and 0.96 of N/Ti respectively. The hardness of Si〓N〓 film decreased dramatically when the free silicon atoms present.

发现薄膜中N原子百分含量主要受氮离子束流和氮气分压的控制,随着氮离子束流和氮气分压的提高,N/Si和N/Ti原子比增加;膜的组织结构则主要受轰击离子束压和基体种类的影响,高的轰击束压可以抑制薄膜的择优取向,金属基体上的晶体缺陷使薄膜易于形成多晶,而单晶硅上的薄膜基本上为非晶态;薄膜的硬度受氮含量的影响最大。

The crystal structures of the two polymorphs are so similar that they can hardly be distinguished by usual polycrystalline X-ray diffraction methods.

后者是一种亚稳相。这两种多型体的结构非常相似,用通常的多晶衍射方法难以区分。

Gain boundary is one of the most important defects in materials, especially in fine-grain materials. It is closely related to the mechanical, chemical and optical properties of materials.

晶界是多晶材料特别是细晶粒材料最重要的缺陷类型之一,与材料的力学性能、化学行为以及光学特性密切相关。

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