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In the present study, the new sensitive and specific LC/MS/MS method was developed for the simultaneous determination of magnesium lithospermate B, rosmarinic acid and lithospermic acid and their major metabolites in biological samples. The pharmacokinetics of S. miltiorrhiza depside salts in dogs, rats, and humans conducted the developed LC/MS/MS method, and they would be useful for new drug development and design.

在此基础上,系统研究了创新中药丹参多酚酸盐多个成分在Beagle犬及大鼠体内的药物代谢动力学特征,包括多剂量、多种给药方式的影响,及吸收、分布、代谢、排泄特征;同时进行人体药物代谢动力学研究,为设计合理给药方案和临床安全有效用药提供了理论依据,对传统中药的现代化研究具有显著的示范作用。

Chinese Cinnamaldehyde Cinnamaldehyde alias, Lauraceae plants are dry skin and cinnamon bark obtained by steam distillation of volatile oil in the main component of research in recent years are more root canal sterilization drug, it can seriously undermine the bacterial cell surface structure, and thus has a wider antibacterial spectrum and strong antibacterial activity; gallnut hundred, also known as worms, insect species are Schlechtendalia Schlechtendalia or times aphid eggs in their parasitic plants Anacardiaceae Rhus chinensis, Green bran Yang Yang, such as bran or red tree gall formation, the main ingredient for gallnut tannin, can solidification microbial protoplasts and a variety of body enzymes, a wide range of bacteria, fungi, yeasts are inhibited.

中药桂皮醛别名肉桂醛,是樟科植物肉桂的干皮及树皮经水蒸气蒸馏得到的挥发油中的主要成分,是近年来研究较多的根管消毒药物,它能够严重破坏细菌细胞表面结构,从而具有较广的抗菌谱和较强的抗菌活性;五倍子又名百虫,是倍蚜种昆虫角倍蚜或倍蛋蚜在其寄生漆树科植物盐肤木、青麸杨或红麸杨等树上形成的虫瘿,其主要成分为五倍子鞣质,能够凝固微生物体内的原生质及多种酶,对多种细菌、真菌、酵母菌都有明显的抑制作用。

Chinese Cinnamaldehyde which also named Cinnamaldehyde alias, is the main component of volatile oil which obtained by steam distillation from dry skin and cinnamon bark of lauraceae plants . It is researched as a root canal sterilization drug in recent years, it can seriously undermine the bacterial cell surface structure, and thus has a wider antibacterial spectrum and strong antibacterial activity; gallnut hundred, also known as worms, it is a kind of gall that be formatted by Schlechtendalia species of insects including Schlechtendalia and times aphid eggs in their parasitic plants Anacardiaceae Rhus chinensis, Green bran Yang or red bran Yang, the main ingredient for gallnut tannin, can solidification microbial protoplasts and a variety of body enzymes, a wide range of bacteria, fungi, yeasts are inhibited.

中药桂皮醛别名肉桂醛,是樟科植物肉桂的干皮及树皮经水蒸气蒸馏得到的挥发油中的主要成分,是近年来研究较多的根管消毒药物,它能够严重破坏细菌细胞表面结构,从而具有较广的抗菌谱和较强的抗菌活性;五倍子又名百虫,是倍蚜种昆虫角倍蚜或倍蛋蚜在其寄生漆树科植物盐肤木、青麸杨或红麸杨等树上形成的虫瘿,其主要成分为五倍子鞣质,能够凝固微生物体内的原生质及多种酶,对多种细菌、真菌、酵母菌都有明显的抑制作用。

Clinical Efficiency of Meningococcus Group A Capsular Polysaccharide Vaccine in Children Three Months to Five Years of Age Cellular and Humoral Components of Monocyte and Neutrophil Chemotaxis in Cord Blood Oral non-absorbed Antibiotics Prevent Infection in Acute non-lymphoblastic Leukemia Aspirin-induced Hepatotoxicity and Its Effect on Juvenile Rheumatoid Arthritis Prediction of Morbidity in Hemophilus Influenzae Meningitis Neurological Sequelae in Children Surviving Mechanical Ventilation in the Neonatal Period Developmental Effects of Prolonged Pregnancy and the Postmaturity Syndrome Long-term Outcome of Hemophilus Influenzae Meningitis Related to Antibiotic Treatment Recommendations for a National Policy on Poliomyelitis Vaccination Impaired Humoral Immunity in Treated Hodgkin's Disease Development of Immune Response during Typhoid Fever in Man In Vitro Susceptibility of Recently Isolated gram-negative Bacteria to Gentamicin, Sisomicin, Tobramycin, and Amikacin Studies of Urticaria and Acute Serum Sickness with the CI Precipitin Test Epidemic Measles in a Highly Vaccinated Population Congenital Chloride Diarrhea Acute Parotitis Associated with Influenza, Type A: Twelve Cases Urinary Tract Infection in high-risk Newborn Infants Maternal ABO Blood Group Type B: A Risk Factor in the Development of Neonatal Group B Streptococcal Disease

脑膜炎双球菌A羣被囊多醣类疫苗接种在3个月到5岁大小孩之临床效果脐带血内单核球及嗜中性球化学向性之细胞成分及体液成分口服不被吸收的抗生素可预防性急非淋巴球性白血症病人罹患感染阿斯匹灵引起之肝毒性及其对幼年性风湿样关节炎之影响流行感冒杆菌脑膜炎预后之预测新生儿时期接受人工呼吸器其日后神经系统上之后遗症过期妊娠及过度成熟徵候对发育之影响流行感冒杆菌脑膜炎之长期预后与抗生素治疗之关系对"小儿麻痹预防接种的国家政策"的建议 Hodgkin's disease治疗后体液免疫之缺损伤寒患者免疫反应的研究目前分离出来的革兰氏阴性菌在体外对Gentamicin,Sisomicin,Tobramycin和Amikacin之感受性荨麻疹和急性血清病CI沉淀素试验的研究在大多数接种人羣发生的麻疹流行先天性氯腹泻与influenza A型病毒有关的急性腮腺炎:12病例报告高危险性新生儿的尿道感染母亲血型B型:为新生儿发生B羣链球菌疾病之个危险因素

The main results were as follows. The main nutrition bioactive components in Opuntia Milpa Alta were analyzed using chemical and instrumental analytical methods. The results showed that the content of crude protein and fat was 0.65%~0.68% and 0.30%~0.31% respectively. The total content of the amino acids was 6.81%~7.38%, and Glu was 1.08%~1.52%.The contents of pectin and cellulose was 1.47%~1.68%, 0.87%~1.22% respectively. They were oxalate free and rich in Ca 5.6%, Fe 8.06mg/100g, Zn 3.30mg/100g, VB6 5.62mg/100g, low in tannin 0.02%~0.04%.The bioactive matter content such as polysaccharide, polyphenol, and flavone were high, about 1.27%, 63.14mg/100g, 36.21mg/100g respectively.

主要研究内容如下:采用化学和仪器分析方法,对米邦塔仙人掌中的主要营养和生理活性成分进行分析,结果表明,粗蛋白含量为0.65%~0.68%,脂肪含量为0.30%~0.31%;氨基酸总量为6.81%~7.38%,其中谷氨酸含量达1.08%~1.52%;果胶、膳食纤维分别为1.47%~1.68%和0.87%~1.22%;干样钙含量5.6%,铁8.06mg/100g,锌3.30mg/100g;B族维生素丰富,其中干样VB6含量5.62mg/100g;单宁0.02%~0.04%;不含草酸;生理活性物质如粗多糖、多酚、黄酮类物质分别约为1.27%、63.14mg/100g、36.21mg/100g,半乳糖约占多糖中单糖总量的80%;HPLC检测出8种酚类物质,绿原酸含量最多达42.40μg/g,其次是芦丁和槲皮素,其含量分别为25.02μg/g和10.91μg/g。

Subsequently,main ideas of polychromatic sets were introduced.

简要介绍了多色集合的主要思想,将概念解设计信息所包含的单元与多色集合的成分相对应,建立了概念产品设计信息基于多色集合的数学描述,以便于产品设计信息的存储、管理和随后设计工作的开展。

It is interpreted that the correlation structure of the allelic polymorphism data contains null correlations introduced by "closure" and the statistical distribution of the data is not normal because of its constant row sum,which resulted in great difficulties in analyzing the data with traditional multiple linear statistical methods such as principal component analysis,factor analysis,cluster analysis and canonical correlation analysis.

长期以来,对于多维基因多态性数据的多元统计分析,如计算遗传距离时所用的聚类分析、分析群体遗传结构时所用的主成分分析、因子分析和典型相关分析等,一直应用为无约束条件数据而设计的经典多元线性分析方法,并没有注意基因多态性数据的"闭合效应"所带来的问题。

Clinical Efficiency of Meningococcus Group A Capsular Polysaccharide Vaccine in Children Three Months to Five Years of Age Cellular and Humoral Components of Monocyte and Neutrophil Chemotaxis in Cord Blood Oral non-absorbed Antibiotics Prevent Infection in Acute non-lymphoblastic Leukemia Aspirin-induced Hepatotoxicity and Its Effect on Juvenile Rheumatoid Arthritis Prediction of Morbidity in Hemophilus Influenzae Meningitis Neurological Sequelae in Children Surviving Mechanical Ventilation in the Neonatal Period Developmental Effects of Prolonged Pregnancy and the Postmaturity Syndrome Long-term Outcome of Hemophilus Influenzae Meningitis Related to Antibiotic Treatment Recommendations for a National Policy on Poliomyelitis Vaccination Impaired Humoral Immunity in Treated Hodgkin's Disease Development of Immune Response during Typhoid Fever in Man In Vitro Susceptibility of Recently Isolated gram-negative Bacteria to Gentamicin, Sisomicin, Tobramycin, and Amikacin Studies of Urticaria and Acute Serum Sickness with the CI Precipitin Test Epidemic Measles in a Highly Vaccinated Population Congenital Chloride Diarrhea Acute Parotitis Associated with Influenza, Type A: Twelve Cases Urinary Tract Infection in high-risk Newborn Infants Maternal ABO Blood Group Type B: A Risk Factor in the Development of Neonatal Group B Streptococcal Disease

脑膜炎双球菌A羣被囊多醣类疫苗接种在3个月到5岁大小孩之临床效果脐带血内单核球及嗜中性球化学向性之细胞成分及体液成分口服不被吸收的抗生素可预防性急非淋巴球性白血症病人罹患感染阿斯匹灵引起之肝毒性及其对幼年性风湿样关节炎之影响流行感冒杆菌脑膜炎预后之预测新生儿时期接受人工呼吸器其日后神经系统上之后遗症过期妊娠及过度成熟徵候对发育之影响流行感冒杆菌脑膜炎之长期预后与抗生素治疗之关系对&小儿麻痹预防接种的国家政策&的建议 Hodgkin's disease治疗后体液免疫之缺损伤寒患者免疫反应的研究目前分离出来的革兰氏阴性菌在体外对Gentamicin,Sisomicin,Tobramycin和Amikacin之感受性荨麻疹和急性血清病CI沉淀素试验的研究在大多数接种人羣发生的麻疹流行先天性氯腹泻与influenza A型病毒有关的急性腮腺炎:12病例报告高危险性新生儿的尿道感染母亲血型B型:为新生儿发生B羣链球菌疾病之个危险因素

The main creating aspects are finding and clarify such a fundamental physical process that the grain boundaries emit vacancies under compressive stress to induce solute non-equilibrium grain boundary dilution and absorb vacancies under tensile stress to induce non-equilibrium grain boundary segregation, formulizing the structural equations and the composition equations in force equilibrium in grain bounary region to describe this physical processes and the kinetic equations for non-equilibrium grain boundary segregation under tensile stress, calculating the modulus in grain boundary region from the expermental data of grain bounday segregation using the structure and coposition equations and calculating the diffusion coefficients of vacancy-solute atom complexes using the kinetic equation simulating the experimental results of grain boundary segregation.

本项目的主要创新点是,发现并阐明了弹性应力场作用下空位与晶界交互作用的基本物理过程:在张应力作用下,晶界会吸收空位,引起溶质非平衡晶界偏聚;压应力作用下,晶界会发射空位,引起非平衡晶界贫化。建立了描述此物理过程的晶界区力学平衡的结构方程和成分方程;?建立了张应力引起的非平衡晶界偏聚动力学方程?;用晶界区力学平衡的结构方程和成分方程?,首次通过实验测量计算出多晶材料晶界区的弹性模量;通过建立的动力学方程模拟实验结果,首次获得溶质原子-空位形成的复合体的扩散系数。

Interpath interference which arises due to non-zero cross and auto correlation of more than one spreading code is suppressed by estimating a transmitted signal stream, or a plurality of such signal streams in the case of a plurality of multipath components, respreading this estimated signal and subtracting non-orthogonal interference contributions from a received signal.

通过估计发射信号流或者存在多个多径成分时的多个信号流、将所估计的信号再扩频、并从接收信号中减去非正交干扰分量,抑制不止一个扩频码的非零互相关和自相关引起的径间干扰。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力