多态的

In the current study, we have detected the mtDNA mutation in lung cancer, investigated the correlation between the mtDNA mutations and carcinogenesis, and explored the possibility of mtDNA mutations as a biomarker. We also analyzed the reasons for the homoplasmic mutations of mtDNA.

为了探讨mtDNA突变在肺癌发生中的意义、mtDNA突变在肺癌早期诊断中作为分子标记的可能性以及mtDNA多态性与肺癌易感性的关系，我们检测了肺癌mtDNA突变，分析了肿瘤中mtDNA同质性突变的形成原因。

This sort of clear division of a population's preferences into two or more large groups indicates that their preferences are idiosyncratically modal.

人们的喜好明显地分为两个或者更多分组的情况表明人们的喜好是特殊模态的。

3Genetic factors play a major role inthe control of immune regulation,such as the expression of cytokines.An analysisof TNF〓 gene polymorphism in IgAN and HSP nephritis is beneficial to better un-derstanding of immunogenetic abnormalities in these diseases.But further inves-tigation on a large scale is necessary in order to find out the susceptibility genes orthe markers for a closely-linked susceptibility locus.

某些免疫相关基因是细胞因子表达、调控的决定因素，本实验通过〓基因多态性分析对部分肾小球疾病的遗传背景进行了有益的探索性研究，但是要最终找到致病基因或者连锁遗传标志，尚有待进一步的大规模研究。

Methods p53 codon 72 were genotyped with pcr-rflp technique for 156 zhuang healthily long-living people (aged 90～105, mean 93.2 years, longevous group) and 142 healthy controls (20～72, mean 34.8 years, control group) from bama area to analyze the polymorphic genotype frequencies.

应用pcr-rflp技术对巴马156例（年龄90～105岁，平均93.2岁，长寿组）健康壮族长寿老人和142例健康壮族成年人（年龄20～72岁，平均34.8岁，对照组）的p53基因进行分型，了解这些基因的多态性，分析该基因频率在长寿组和对照组之间的差异及其与长寿的关系。

Therefore the nonrandom distribution of 3′ end sequences of effectual primers in tomato RAPD reflected the sequence-specific structure may occur in tomato genome at flank of polymorphic regions. It is probably an attribute of tomato genomic sequence and is common in Lycopersicon.

RAPD引物3′端序列的非随机分布，反映了番茄基因组内的多态性区段侧翼具有序列的特异性，这种特异性结构应是番茄基因组序列的一种属性，这种属性为番茄属基因组所共有。

Randomly amplified polymorphic DNA and inter-simple sequence repeat markers were used to analyse the genetic diversity and relationships of 20 species in 6 genera from Magnoliaceae and compare the genetic difference among generas with inner genera, combining the other research results, the systematic of 20 species in 6 genera was primarily discussed. The purpose of this study was to provide scientific basic data for systematic and other research on Magnoliaceae.

应用RAPD和ISSR标记对木兰科6属20种植物的遗传多态性和亲缘关系进行分析，比较属间、属内的遗传差异，并结合前人的研究结果，对木兰科6属及属下类群的系统位置进行探讨，旨在为木兰科植物的系统分类及其它研究提供实验依据。

Among 76 nonpregnant women in the study,40 of whom had given birth to infants with NTDs and 36 control women previously had normal offspring.

本研究利用采集的外周血标本，检测CBS第833位和第919位核苷酸的多态性，初步探讨了CBS的基因突变与NTDs之间的潜在关联。

The chromatin unfolding assay showed that ,like the wild-type transactivation domain, two variants that represent benign polymorphisms did not induce chromatin unfolding or only induced subtle change. Contrary to the behaviors of the wild type and two benign variants, four cancer-predisposing mutations in the transactivation domain superactivate the chromatin unfolding. The results suggest that the chromatin unfolding assay can aid in the characterization of deleterious mutations in the C-terminal transactivation domain of BRCA1 and may provide more reliable presymptomatic risk assessment.

对这些重组质粒的染色质伸展活性检测表明，野生型pwt和两种良性多态性突变体不具有染色质伸展活性或只有极微弱的染色质伸展活性，而其他4种乳腺癌易感突变体均具有过强的染色质伸展活性，提示利用染色质伸展技术可预测BRCA1转录激活区基因型与乳腺癌发生风险的表现型的关系。

According to indexes of PIC,they could be used in molecular analysis in prunus,proving selectable primers and diversity for the experiment accessions directly perceived through the senses.

根据多态信息量的指标，为桃及其李属近缘种植物的分子生物学分析，提供直接可供选择的引物和比较直观确定供试样品的遗传多样性。

Methods Case control association study was adopted to analyze the association between the 48 bp VNTR polymorphism of DRD4 gene exon III in 510 DSM IV schizophrenics and 171 psychiatrically normal controls.

使用病例对照的关联分析的方法，对符合诊断标准的 5 10名精神分裂症患者/ 171名正常对照就DRD4基因第三外显子 48bpVNTR的多态性进行检测并进行关联分析。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。