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In nuclear style families, to study the genetic association and linkage relationship and to provide the genetic basis information for the further research. Methods: We investigated the genetic structure and relationship of 116 Keshan Disease patients and 65 local normal people in Shaanxi province with HLA-DRB1 locus, which is characterized by high polymorphism and inheritage stability, with polymerase chain reaction-sequence specific oligonuclotide probe.

本研究选用具有高度多态信息量及遗传稳定性的人类HLA-DRB1遗传位点,以陕西118名克山病人及当地65名正常对照人群作为研究对象,用聚合酶链反应—序列特异性寡核苷酸探针的方法对其遗传结构及其相互关系进行了分析研究,并在核心家系中采用基于单体型的相对风险及传递不平衡检验对其遗传指标进行了统计计算。

In humans, a polymorphism for haptoglobin associated with increased cardiovascular disease is also characterized by increased lesional iron.

在人类,结合珠蛋白基因多态性与心血管疾病的增加有关也是以皮损铁的增加为特征的。

Study on the genetic polymorphisms of Mamu is good to the development of biological disciplines and various experiments with Macaca mulatta as animal model.

因此,恒河猴MHC多态性的研究,有助于生物科学的发展及指导以恒河猴为动物模型的各种实验。

The paper is to research physiological differentiation and DNA polymorphism of MLP. The main result is as follows: 1.Investigating the Poplar Resistance: the difference of sensitivity is prominent.Other poplars are infected by Melampsora larici-populina in different degree, except that Populus deltoids and Populus deltoides×P.

本论文主要是对来自西北,华北,东北和西南等省的多种落叶松—杨栅锈菌进行同工酶分析以及DNA多态性研究,得出如下结论:(1)寄主抗病性调查:杨树各派树种对落叶松杨栅锈菌的感病性差异明显,除美洲黑杨和中绥12号外,所有的杨树品种都不同程度地感染了落叶松杨栅锈菌。

Karyotypic findings showed that all cultivars were mixoploid with chromosome number ranging from 49 to 57, and 54 was the most frequent number observed.

结果表明:(1)17个栽培小菊均为混倍体,染色体数在49~57之间变异,以54条为主;(2)染色体呈现多态性:多数品种由中部、近中部和近端部着丝粒染色体组成;最长与最短染色体的比值为1.62~2.39;臂比>2的染色体所占的比率为11.11%~29.62%;核型不对称系数为59.74%~63.37%;3个地被菊品种和'奥运橙光'、'金陵白凤'(2n=53)核型类型为&2B&,其它品种为&2A&型。

The result showed that: 148 poly morphic hands were detected by use of, 22 RAPD primer and 158 allele were detected by use of 34 SSR primer.

利用筛选出的22条RAPD引物,检测到了148条有多态性的带;利用筛选出的34对SSR引物,检测到158个等位基因。

Only two alleles were detected,the repeating number of which are 13 and 19 respectively,which indicated that it is a low poly morphic microsatellite marker.

对莱芜猪、长白猪、大白猪、杜洛克、皮特兰、民猪和二花脸7个品种的381个无关个体的检测均显示该基因座只有两个等位基因,重复数分别为13和19;是一种多态性较低的微卫星标记。

Microsatellite markers are used to analyze the genetic background of KM outbred mice from Shanxi. The two populations were bred by mating in an outbred manner for nine generations and nineteen generations (named A9 and A19 respectively). Seven SSR markers located on seven different chromosomes were utilized in this research, D3Mit22 was selected for detailed analysis.

应用微卫星分子标记对昆明小鼠封闭群相隔10代的两个群体(分别命名为A9和A19)进行遗传背景分析,共设计位于小鼠7条染色体上的7对微卫星引物用于实验研究,选取具有多态性的一个微卫星位点D3Mit22进行详细分析。

Results:(1) totally, the distributions of alleles o r genotypes of drd3 ser9gly polymorphism are not significantly different between the groups of paren ts, unaffected-siblings and affected-siblings, and between the sub-types of schi zophrenia.

对drd3基因的ser9gly多态性进行检测。结果:(1)总体而言,drd3基因的ser9gly等位基因频度和基因型频度在父母组、非患病同胞组和患病同胞组之间差异无显著性,在精神分裂症不同亚型之间基因型频度和等位基因频度的分布差异也没有统计学意义。

Morphological traits and living habit of Tibetan chicken, which is an aboriginal chicken breed on plateau with its own characteristic populational genetic features, are in great common with the Red Jungle Fowl, the assumed ancestry of domestic chicken.

为了有效保护并合理利用这一遗传资源,我们采用多重PCR与半自动荧光标记微卫星聚丙烯酰胺凝胶电泳相结合的方法检测了20个微卫星基因座的多态性,并随机抽取藏鸡群体中部分个体进行个体体形特征与生产性能的统计。

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