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The genic polymorphism is that there are two or more genotypes in the same locus of chromosome in the group of random mating. It is an important factor to determine the susceptivity of desease, the diversity of clinical symptom and the reaction of medication.

所谓基因多态性是指在一随机婚配的群体中,染色体同一基因座位点上有两种或两种以上的基因型,它是决定人体对疾病易感性、临床表现多样性及药物治疗反应差异性的重要因素。

DNA fingerprinting for Taraxacum mongolicum and its adulterants of six species of Compositae was demonstrated with random primed polymerase chain reaction including arbitrarily primed PCR and random amplified polymorphic DNA.

采用分子生物技术包括任意引物聚合酶链式反应和随意引物扩增的多态性DNA方法扩增蒲公英及其6种土公英混淆品的基因组DNA,获得清晰可靠的DNA指纹图谱。

If RB1 molecular genetic testing is not available or is uninformative, indirect testing using polymorphic loci linked to the RB1 gene can be used in familial RB to clarify the genetic status of at-risk family members.

如果无法对 RB1做分子遗传学检测或检测无有效信息,用与 RB1基因连锁的多态位点进行间接的检测同样能用于在家族性 RB 中阐明易感家族成员的遗传状况。

Since all objects in the class pool are upcast to their common base class, the polymorphism of the method leads to that which object method will be executed can only be ascertained at runtime.

由于所有位于对象池中的对象都被上溯到它们的基类型,方法多态使得只有在运行时刻才能真正确定到底哪个对象的方法被执行。

By adding some fluorescence group in the reaction,we can utilize the fluorescence signal to accumulate and monitor the whole PCR process,and finally through the standard curve,we could analysis the unknown sample.As this technology has the characteristics of strong peculiar,high sensitivity,fine repetitiveness and accurateness,fast and totally closed raction,so in diagnosing animal virosis,this technology not only can measure the power and distribution of pathogen infection in the organism,and also it still has sensitive,fast,convenient characteristics.

该技术实现了PCR从定性到定量的飞跃,同常规PCR法相比,该方法特异性和可靠性更强,能实现多重反应,且采用了完全闭管检测,不需PCR后处理,有效解决PCR污染问题以及EB对试验人员的伤害;再配以相应的荧光PCR仪,使整个PCR过程实现自动化,加之具有耗时短,操作方便等特点而备受推崇,因而广泛应用于基因表达研究、转基因产品安全检测、单核苷酸多态性研究及病原体检测等领域。

Objective To investigate the relationship of excision repair cross-complementing 1(ERCC1), xeroderma pigmentosum group D, and breast cancer susceptibility gene 1(BRCA1) polymorphisms with the efficacy of platinum-based chemotherapy for treatment of the patients with advanced non-small cell lung cancer.

目的 探讨核苷酸切除修复系统的3个重要基因切除修复交叉互补基因1(ERCC1)、着色性干皮病基因D和乳腺癌易感基因1(BRCA1)的单核苷酸多态性与晚期非小细胞肺癌患者铂类药物化疗效果的相关性。

The rapid acetylator would increase the heterocyclic amines from pre-carcinogen to active formation.

随着MTHFR 667 C->T的多态基因在基因组中比例升高,其腺瘤复发有下降的趋势,而且饮酒与红烧鱼因素的相对危险度也呈下降趋势。

The distribution of NAT2 polymorphisms was different between the recurred group and the control group. The polymorphism of NAT2 would increase the risk of recurrence in the population with history of rectal adenoma. However, there is no difference for NAT2 rapid and slow acetylator between two groups.

NAT2多态性在腺瘤复发组与对照组中的分布是有差异,NAT2非野生纯合型(Wt/M〓+M〓/M〓)为直肠腺瘤复发的危险因子,特别当在非野生纯合型中的NQO 1 C/T+T/T型及MTHFR C/T+T/T,其相对危险度分别可达:3.27(95%CI 1.01-10.65,P=0.043)和3.28(95%CI1.00-10.84,P=0.046)。

Variance of the sequences comes from accumulated mutation.These properties make them unique and important not only to anthroponomy and genetics but also to forensic science and medicine.

由于 Y染色体的这些特点,使得对 Y染色体上多态性遗传标记的研究不仅在人类进化学、遗传学等方面意义重大,而且在法医学、临床医学等方面亦具有重要而独特的应用价值

Twenty-three isolates of gray leaf spot pathogen, Cercospora zeae-maydis, collected from growing area of Northern China were clustered based on their soluble protein and isozyme profiles obtained through native PAGE in order to base physiologically the pathogen differentiation at protein or isozyme level.

利用聚丙烯酰胺凝胶电泳技术,对采自北方玉米主产区的23个玉米灰斑病菌菌株进行可溶性蛋白质和同工酶电泳图谱分析及聚类分析,从蛋白质和酶学的多态性水平上分析玉米灰斑病菌的生理分化特征。

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