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This study was aimed to find single nucleotide polymorphism in the promotor region of asparagine synthetase gene and to determine if these SNPs have influence on the transcriptional activity of AS promotor.

本研究旨在通过筛查发现AS启动子区的单核苷酸多态性位点,研究它们对AS基因表达量的影响及寻找对Lasp治疗反应具有影响的个体遗传因素。

In each case, only one of the two possible expected ratios was accepted in all markers, furthermore, no significant deviation from Mendelian inheritance (two-tailed binomial test, P≥0.053). To investigate the polymorphism of AFLP markers, and the genetic diversity in populations of H. discus hannai, eight abalone populations were analyzed by using a total of six AFLP primer combinations. The mean percentages of polymorphic loci of the eight populations were 48.65%, 50.50%, 51.17%, 50.51%, 58.90%, 60.07%, 68.92% and 54.05%, respectively.

皱纹盘鲍群体多样性研究中,选取的6对AFLP引物组合在8个皱纹盘鲍群体内均能扩增出清晰、可重复的扩增产物,扩增带型差异明显。8个群体的多态位点比率分别为:大连养殖群体48.65%、烟台养殖群体50.50%、青岛胶南养殖群体51.17%、青岛崂山养殖群体50.51%、山东长岛野生群体58.90%、山东俚岛野生群体60.07%、日本岩手野生群体68.92%、大连野生群体54.05%;预期杂和度分别为0.2291、0.2438、0.2442、0.2374、0.2626、0.2723、0.3137和0.2802。

This article reviews Transforming growth factor-beta-β about its bionomics,biological function,gene polymorphism,and its relationship with aging.

本文就转化生长因子β基因的生物学特性、生物学功能、基因多态性及其与衰老的联系作一简要的综述。

T. tarda and 13 microsatellites from Houbara bustard were detected in 47 great bustards (O. t. dybowskii).

微卫星DNA研究显示,从3个大鸨指名亚种的微卫星位点和13个波斑鸨的微卫星位点中筛选出8个具有多态性的位点。

In analyzing the symmetrical element features of power system, the definition of circulator element and circulator node is developed.

通过对相分量法短路故障处理的分析,以定长度向量方程的多态相分量法为基础,提出了用于处理电力系统短路故障的残量变换法和残压变换法。

Prolactin receptorgene was studied as a candidate gene for the prolificacy of Jining Grey goats. Eight pairs of primers were designed to detect single nucleotide polymorphisms of exon 3 to exon 9 and intron 9 of PRLR gene in both high fecundity breed and low fecundity breeds (Liaoning Cashmere goat and Angora goat) by PCR-SSCP.

设计8对引物,采用PCR-SSCP技术检测催乳素受体(prolactin receptor,PRLR)基因外显子3至外显子9和内含子9在高繁殖力山羊品种和低繁殖力山羊品种(辽宁绒山羊、安哥拉山羊)中的单核苷酸多态性,同时研究该基因对济宁青山羊高繁殖力的影响。

According to the heredity diversity indexes described above of the five goat breeds, Guanzhong dairy goat had the most abundant heredity diversity and showed high polymorphism, and Xinong Saanen dairy goat and Shaannan white goat were inferior, while Angora goat and Boer goat had the lowest genetic variability.

分析结果显示,关中奶山羊的遗传多样性最丰富,表现为高度多态;其次是西农萨能奶山羊和陕南白山羊,而安哥拉山羊和波尔山羊的遗传变异程度最低。

The follicle-stimulating hormone beta-subunit gene was studied as a candidate gene for the prolificacy in Jining Grey goats. According to the sequence of ovine FSHβ gene, nine pairs of primers were designed to detect single nucleotide polymorphisms of 5' regulatory region, exon 1 and exon 2 of FSHβ gene in both high fecundity breed and low fecundity breeds (Liaoning Cashmere goat, Boer goat and Angora goat) by PCR-SSCP.

采用PCR-SSCP技术检测促卵泡素β亚基(follicle-stimulating hormone β, FSHβ)基因5'调控区、外显子1和外显子2在高繁殖力山羊品种和低繁殖力山羊品种(辽宁绒山羊、波尔山羊、安哥拉山羊)中的单核苷酸多态性,同时研究该基因对济宁青山羊高繁殖力的影响。

Single nucleotide polymorphism in exon 1 and 3 of fibroblast growth factor (FGF5) gene was studied by DNA sequencing in Yingjing angora rabbit, Tianfu black rabbit and California rabbit.

通过PCR产物直接测序的方法,对荥经长毛兔、天府黑兔以及加利福尼亚兔的 FGF5基因外显子1和外显子3进行单核苷酸多态性分析。

The results of FOXC2 expression profile in human embryos suggest that mutations in FOXC2 gene could lead to cardiovascular and axial skeleton development defects in human, and there are novel polymorphisms of FOXC2 gene in Han people.

根据FOXC2在人胚的表达模式,提示该基因变异可能导致人心血管和中轴骨骼发育缺陷;在汉族人群可能存在新的FOXC2基因单核苷酸多态性。

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