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AIM: To determine the distribution and frequency of functionally important allelic variants in the cytochromes P450 2C19, arylamine N-acetyltransferase 2 (NAT2), and thiopurine S-methyltransferase genes in the Han Chinese population and compare them with those of other ethnic populations.

目的: 了解细胞色素P450(cytochromes P450,CYP)2C19,N-乙酰基转移酶2(arylamine N-acetyltransferase 2,NAT2)和硫嘌呤甲基转移酶(thiopurine S-methyltransferase,TPMT)基因常见的遗传多态性在河南地区汉族人群中的分布及其频率。

In searching for RAPD marker linked to the genes controlling brachytic stem, 260 RAPD primers were applied to screen four parents of three combinations and RIL. Polymorphic bands revealed by the primer S-506 exhibited the best repeatability among all primers.

利用4个亲本和1个重组自交家系筛选260个RAPD随机引物,其中有1个引物S-506扩增出的多态性条带有较好的重复性。

Significant differences in cytosine methylation level among the three tissues and the same changing tendency in two inbred lines were detected. Both MSAP (methylation sensitive amplification polymorphism) ratio and full methylation level were the highest in bracteal leaf, and the lowest in tassel.

结果表明,3个组织甲基化水平存在一定差异,并在两自交系中表现出相同的变化趋势,即雌穗苞叶的甲基化敏感扩增多态性比率和全甲基化率最高,穗位叶次之,雄穗最低。

The results were the basic information to further study SNPs of MC1R gene associated with plumage color on mule duck. By using the program of Blast on GenBank, the results indicated that duck had homology with 98.4% homology with branta bernicla at nucleotide level of MC1R gene, and 92.8%~98.2% homology with other birds.

为进一步研究半番鸭羽色MC1R基因单核苷酸多态性奠定了基础;通过BLAST进行相似性搜索,结果表明,鸭与黑雁MC1R基因的核苷酸序列同源性最高为98.4%,与其他家禽的同源性也保持在92.8%~98.2%之间。

In this study 24 cpSSR primer pairs were screened, and four pairs were found producing DNA fragment length polymorphism from the tested populations of Castanea mollissima.

对24对cpSSR通用引物进行筛选,选用4对呈现多态性的引物对板栗的4个野生居群和9个地方品种群进行遗传分析。

There are several characters in our researches:(1) we study the relationship between karyotype polymorphism and sex chromosome in Elaphodus Cephalophus which only lives in China, and explore the mechanism of its sex chromosome evolution.

研究特色主要体现在:一、以我国特有的动物毛冠鹿为材料,在染色体和DNA水平上研究毛冠鹿核型多态与性染色体关系,探索毛冠鹿性染色体发生和演变的机制。

Aims To investigate whether a common polymorphism in the cholesteryl ester transfer protein gene modifies the relationship of alcohol intake with high-density lipoprotein cholesterol and risk of coronary heart disease.

摘要翻译:目的是研究饮酒、高密度脂蛋白胆固醇和冠心病风险是否在胆固醇酯转运蛋白基因改变有一个共同的多态性的关系。

Another area that remains to be explored is the relevance of human heart chymase gene in any effects on coronary heart disease.

CMA G1903A基因多态性与冠心病及冠状动脉病变程度无关,但可能与血脂和肥胖有关:AG型可能是肥胖发生的危险因素,而AA型可能是高脂血症的保护因子。

Objective To investigate the correlation between the functional genetic variations of angiotensin-converting enzyme and Chymase genes and the risk of atrial fibrillation in hypertensive patients with left ventricular hypertrophy. Meth- ods From Dec.

目的 探讨高血压左心室肥厚患者血管紧张素转换酶基因和Chymase基因的多态性与心房颤动的相关性。

The effect of CYP polymorphisms on the clinical outcomes in patients treated with prasugrel remains unknown.

CYP多态对接受普拉格雷治疗的患者临床结果的影响还不清楚。

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