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Methods The polymorphisms of eight STR loci in 87 normal persons and 8 haemophilia B families were assayed by PCR and genescan, and the linkage relations were analysed.

应用PCR和Genescan等方法分别检测 87名正常人和 8个血友病B家系(35人)的 8个STR位点的多态性,并进行家系遗传连锁分析。

For A3854G locus, Luxi cattle's and Hereford cattle's genotype distribution are significantly different with others, genotype distribution of other loci is identical.

这4个位点在遗传特性上表现为极大的相似性,各群体的遗传多态性较低。

In the progress of tumor development, it shows heterology, and formed different subgroup, promote metastasis.

其表现为肿瘤在组织形态学、核型,免疫表型,遗传标志物,生长率,细胞产物,药物敏感性以及其他细胞组织学特征方面呈现广泛的多态性,从而产生不同转移能力的癌细胞。

Namely 706 A→G in FZD5, 51661 absence of T, 57257 C→T and 71187 AG heterozygosis in LOC729607. The mutation could also be found in heath adult and checked by NCBI, which was polymorphism of single nucleotide.

所检测到的变异在家系中患者和正常人中都存在,在NCBI数据库中能查到相应的位点,是单核苷酸多态。

Average heterozygosity and polymorphic information content of 23 microsatellite loci were 0.6285 and 0.5496, respectively.

群体表现出较高的平均杂合度和平均多态信息含量,分别为0.6285和0.5496,说明雪峰乌骨鸡自然群体具有较丰富的遗传多样性。

The frequency of TNFβ+252 locus GA heterozygote may be related to the prognosis of SARS.

结论TNFβ+252位点的基因多态性与严重急性呼吸综合征发病易感性无关,但TNFβ+252位点G/A杂合子频率与严重急性呼吸综合征的预后有关。

Results Among 54 WD patients, 36 were found to carry Arg778leu mutation, among whom 15 were homozygote, 21 were heterozygote, the frequency of this mutation was 47.2%. Of 46 patients with hepatic damage, 36 were found to have the mutation of Arg778Leu, among whom 34 were found to have Leu770Leu polymorphism simultaneously.

结果 54例Wilson病患者中36例存在Arg778Leu基因突变,15例为纯合型,21例为杂合型,Arg778Leu等位基因突变频率为47.2 %;46例伴肝损害的患者中33例存在ATP7B基因外显子8的Arg778Leu突变;36例Arg778Leu突变者中34例同时伴有Leu770Leu多态性。

The balance between cell survival and apoptosis is crucial for normal development and homeostasis of multicellular organisms.

细胞存活与凋亡之间的平衡是多细胞生物正常发育与稳态的关键。

There were totally 22 alleles of these microsatellite loci, and the number of alleles per locus ranged from 2 to 6. The average homozygosity, average polymorphism information content and average heterozygosity was 41.67%, 0.488 and 0.5833, respectively.

对这6个位点的扩增产物进行分析,结果显示:6个位点共检测到22个等位基因,每个位点的等位基因数从2个到6个不等;平均基因纯合率为41.67%,平均多态信息含量为0.488,平均杂合度为0.5833。

The further analysis was given to Rhesus boxes specific sequencing and RHD gene homozygosity determined by PCR-restriction fragment length polymorphism analysis to Rhesus boxes.

然后对Rh盒子基因进行特异性测序分析,同时对Rh盒子基因的扩增产物采用聚合酶链反应-限制性片段长度多态性(restrict fragment length polymorphism,RFLP)方法进行RHD基因的纯合性测定。

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