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Their feature on histology not is apparently, well differentiated liposarcoma with well fattiness tumor as well as dedifferentiated liposarcoma with malignant shuttle shape / much shape do not break up tumor distinguish is still a baffling problem.

它们在组织学士特征不是很明显,高分化与良性脂肪性肿瘤以及去分化与恶性梭形/多形未分化肿瘤的鉴别仍是一个难题。

ALCL was not uncommon in children. The differential diagnoses included malgnant histiocytosis, T zone or pleomorphic T-cell lymphoma, Hodgkins lymphoma, mycosis fungoides, and metastatic carcinoma.

小儿间变性大细胞性淋巴瘤并不少见,需与恶性组织细胞增生症、T区或多形T淋巴瘤、霍奇金淋巴瘤、蕈样霉菌病和转移性癌等鉴别。

Methods We reported a case of PXA located in the cerebellum of a young adult in view of its extremely unusual location. Morphologic observation, immunohistochemical staining using DAKO EnVision system , histochemical stains including hematoxylin eosin and Gordon Sweet's reticulin methods were used.

采用免疫组织化学DAKOEnVison法、组织化学网质纤维染色和HE染色及形态学观察的方法,报道 1例极罕见于年轻人小脑的多形性黄色星形细胞瘤,探讨其临床病理特点。

Objetive:To investigate the histopathological features and detect the mutation of JAK2V617F in PV、ET and IMF;to analyze the effects of the stages of myelofibrosis and the mutation on the number of leucocyte in PV and ET patients;Methods: the morphological features of 69 patients who dignosed in the first time were studied by HGF and Gomori stains ; the mutation of JAK2V617F was detected in 38 blood or marrow samples of PV、ET and IMF patients by real-time PCR;the effects of the stages of myelofibrosis and the mutation on leucocytes were analyzed;Results: Different stages of reticulin were observed in 15 PV and 15 ET patiens'marrow sections,and the cytosis、the pleomorphism and the bone trabecula side location of megakaryocytes were observed in all PV、ET and IMF patients;the means of leucocyte in patients with and without JAK2V617F were 20.4×109/Land 11.4×109/L respectively;the P value was 0.367 as comparing the leucocytes among different stages of reticulin increasing.

目的:探讨PV、ET、IMF患者的骨髓病理特点并且检测JAK2V617F突变的发生率,分析骨髓中纤维增生程度以及JAK2V617F对PV、ET患者白细胞数的影响;方法:69例初诊患者的骨髓切片经HGF染色以及Gomori染色后进行形态学研究;并利用real-time PCR法测38例患者的骨髓或者外周血的JAK2V617F突变;分析骨髓切片中纤维组织增生程度以及JAK2突变对患者白细胞数的影响;结果:15例PV和15例ET患者的骨髓切片中可以观察到不同程度的纤维组织增生,所有PV、ET、IMF患者骨髓病理中可见到巨核细胞增多、巨核细胞多形性改变以及巨核细胞定位于骨小梁旁;12例PV、4例ET、4例IMF中检测到JAK2V617F;有突变和无突变患者发病时白细胞数均值分别为20.4×109/L和11.4×109/L,比较不同纤维增生程度的PV、ET患者的白细胞数均值,P值为0.367。

The tumor cells are large in size, very pleomorphic, and have abundant, vacuolated to dense cytoplasm, and hyperpchromatic nuclei with irregular contours and prominent nucleoli.

瘤细胞个大,多形性明显,浆丰,胞浆从空泡状到致密,核深染,外形不规则,核仁明显。

The other cells showed pleomorphic nuclei pyknosis, vacuolization showed symptoms, small size, with rows or clusters, sometimes we can see some acini.

另一类细胞则呈多形性,细胞核固缩,呈空泡状,体积小,成排或成簇排列,有时可见一些腺泡。

Our laboratory has demonstrated the presence of this safrole-DNA adducts in oral tissue from oral cancer patients.

本研究以侦测人类白血球之黄樟素DNA键结物,作为咀嚼槟榔者黄樟素暴露的指标,并探讨其与咀嚼槟榔和CYP1A1及CYP2E1基因多形性之间的关系。

Results Tag was found in all of 8 ependymomas, 2 choroid plexus papillomas, 2 human glioma cell lines, 90% of pituitary adenomas (9/10), 73% of astrocytomas (11/15), 70% of meningiomas (7/10), 50% of glioblastomas multiforme (4/8), and 33% of medulloblastomas (2/6). None of the 8 normal brain tissues were positive for Tag, nor were 5 oligodendrogliomas and 1 pineocytoma.

结果 Tag在8例室管膜瘤、2例脉络丛乳头状瘤及2株人脑胶质瘤细胞系中全部表达;垂体腺瘤Tag阳性率为90%(9/10),星形胶质细胞瘤73%(11/15),脑膜瘤70%(7/10),多形性胶质母细胞瘤50%(4/8),髓母细胞瘤33%(2/6);5例少枝胶质细胞瘤、1例松果体瘤及8例正常人脑组织无Tag表达。

Torsades de pointes is a special form of polymorphic ventricular tachycardia. It is characterized by continuously changing morphology of the QRS complexes that seem to twist around an imaginary line, rate dependence, underlying QT prolongation and the so called "long-short initiation sequence".

Torsades de pointes是一种特殊形态的多形性心室频脉,其心电图的特徵包括:QRS波的形态会一直改变,彷佛缠绕著一条假想的线;另外它的发作常与心博过缓有关,合并有QT间距延长,及以所谓「长-短」的序列而开始。

Methods and Results— The outcome in 101 catecholaminergic polymorphic ventricular tachycardia patients, including 50 probands, was analyzed.

方法和结果――作者分析了101例儿茶酚胺介导的多形性室速患者,包括50例先证者,平均随访7.9年。

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