多巴胺

An ahead of print epub ofa studywith rats by S Chalon of the Universite Francois-Rabelais de Tours, France reveals that a diet seriously deficient in omega 3 polyunsaturated fatty acids duringgestation and lactation was associated with alterations in the brain pool of serotonin and dopamine, and that attempting to correct the deficiency in lactation did not completely reverse the negative effects of the prior deficiency.

一个提前打印epub的一项研究显示，与鼠用S chalon的大学弗朗索瓦-拉伯雷德之旅，法国揭示了一个饮食严重不足，在欧米茄-3多不饱和脂肪酸，在妊娠期和哺乳期，是与改建，在脑池的羟色胺和多巴胺，并试图纠正缺陷，在哺乳期并未完全扭转负面的影响，事先缺乏症。

The neurological functional recovery of stroke rats is assessed by Longa 5 grades. Sucrose solution consumption test and open-field test are used to estimate the change of interest, the level of spontaneous motor activities and investigative behavior of PSD rat model. Fluorophotometry is applied to detect the monoamine neurotransmitters(NE 5-HT and DA) of the double frontal-parietal cortexes and brain stem.

运用Longa 5分法评定卒中大鼠神经功能；运用糖水消耗实验、敞箱实验评定PSD大鼠的抑郁行为学改变；采用荧光分光度法测定双侧额顶皮层及脑干的单胺递质：去甲肾上腺素、5-羟色胺(5-HT)、多巴胺的含量。

On the basis, further isolated-living condition and moderate unpredictable stress are applied successively to set up PSD rat model . The neurological functional recovery of stroke rat is assessed by Longa 5 grades and horizontal bar test.Sucrose solution consumption test, open-field test and passive avoid test are used to estimate the change of interest, the level of spontaneous motor activities and investigative behavior of PSD rat model.Fluorophotometry is applied to detect the monoamine neurotransmitters(NE,5-HT and DA) of the double frontal-parietal cortexes and brain stem. Investigating the action of YuLeShu on the neurological functional recovery of stroke rat.

运用Longa5法和水平木棒法评定卒中大鼠神经功能恢复；运用糖水实验、敞箱实验、被动躲避实验评定PSD大鼠的兴趣感变化和自发活动、探究行为等抑郁行为学改变；采用荧光分光度法测定双侧额顶皮层及脑干的单胺递质：去甲肾上腺素(Norepinephrine，NE)、5-羟色胺(5-Hydroxytryptamine，5-HT)、多巴胺(Dopamine，DA)含量。

MAIN OUTCOME MEASURES: The contents of monoamine neurotranmitters of norepinephrine, adrenalin, dopamine and 5-serotonin (5-HA) and its metabolites of DHPR, 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid in the striatum and marginal area of brain in rats were observed.

主要观察指标：大鼠纹状体和脑边缘区单胺类递质去甲肾上腺素、肾上腺素、多巴胺和5-羟色胺及其代谢产物3，4-二羟苯乙二醇、5-羟吲哚乙酸、高香草酸的含量。

MAIN OUTCOME MEASURES: Content of monoamine transmitter such as levarterenol, adnephrin, dopamine, indoleacetic acid, homovanillic acid and 5-serotonin.

主要观察指标：测定各组大鼠脑组织单胺类神经递质去甲肾上腺素、肾上腺素、多巴胺、吲哚乙酸、高香草酸和5-羟色胺的含量，并进行组间对比。

Immunohistochemistry technology was used to evaluated tyrosine hydroxylase of DA synthesis. DA, 5-hydroxytryptophan(5-HT) and their respective metabolic products 3,4 -dihydroxyphenylacetic, homovanillic are also precisely quantified in this research by using high-pressure liquid chromatography with electrochemical detector. The main metabolism monoamine oxidase of DA was processed too. RESULTS:WD can increase the synthesis and the metabolism process of DA .

本文观察了温胆汤及其配伍对大鼠刻板行为的影响，采用了免疫组化技术对多巴胺的合成酶—酪氨酸羟化酶进行了含量测定，应用高效液相-电化学法测定了DA、5-羟色胺（5-HT）及代谢产物3，4—二羟基苯乙酸、高香草酸的含量，并测定了DA主要降解酶—单胺氧化酶。

Serotonin (5-HT), its precursors tryptophan and 5-hydroxytryptophan (5-HTP), major metabolites 5-hydroxyindoleacetic acid (5-HIAA); and 3-methoxy-4- hydroxyphenylethylene glycol , homovanillic acid , the respective major metabolites of noradrenaline and dopamine were measured by a method of HPLC.

应用高效液相色谱法测定其中5—羟色胺（5-HT）系列代谢物：色氨酸、5-羟色胺酸（5-HTP）、5-HT、5-羟吲哚乙酸（5-HIAA）；多巴胺的主要代谢产物3-甲氧基-4-羟基苯乙酸；去甲肾上腺素的主要代谢产物3-甲氧基-4-羟基苯乙二醇等。

Objective To study the effect of Borna disease virus infection on the transcription of monoaminergic receptor genes in the brain tissues of neonatally inoculated rats.

目的分析博尔纳病病毒感染对新生大鼠脑内单胺类受体基因转录的影响。方法选择病毒滴度为2·0×106FFU/ml的BDV病毒液对新生大鼠进行颅内接种，接种量为10μl/只新生大鼠。30d后用RT-PCR和间接免疫荧光方法确定BDV感染情况；并采用半定量RT-PCR方法检测BDV感染大鼠脑组织中多巴胺2(D2)受体和5-羟色胺2α(5-HT2α)受体基因的mRNA转录情况。

REID: Chemically, it involves surging brain elements called monoamines, dopamines, norepinephrine, and serotonin.

化学上来说，这涉及到大脑与所谓单胺类的作用，例如多巴胺、去甲肾上腺素和羟色胺。

The results obtained suggest that like the analgesic action of morphine, there is an antagonistic modulation by monoamines of morphineinduced respiratory depression, i. e. 5-HT and DA function as the depressant mediators and NE as an excitatory mediator, and that a central #alpha#-adrenergic system is involved in the action of morphine on the respiratory centers.

上述结果提示中枢内存在的单胺类拮抗性调制系统在吗啡的呼吸抑制效应中起一定作用，5-经色胺和多巴胺系统加强吗啡的呼吸抑制效应，去甲肾上腺素系统则相反，后者的作用是通过，一受体而不是户受体实现的。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。