多层化

Electrical Resistance Tomography is a novel cross section measurement technology developed in recent years. It can achieve the visualization measurement of multi-phase media component parameter in the closed pipe and process vessel inside. It is adequate for two/multi phase flow process that the conductive liquid is continuous phase.

电阻层析成像(Electrical Resistance Tomography，简称ERT)技术是近年来发展起来的一种高新检测技术，可实现对封闭的管道或过程容器设备内部多相组份物质参数的可视化测量，适用于两相流/多相流中以液相为连续相的生产过程，是过程层析成像技术中的一个研究热点。

The information integrated pattern based on PDM/PLM in the course ofmanufacture is put forward. Under the constraints of building CAPP platform, thearchitecture of CAPP platform is established. The models of decision making andfunction for process planning are given. Then the development means of CAPP basedSmarTeam are extracted.3. The structure of modular product life cycle is established. Toward the divisionand planning of the General Modules oriented product family, theCAD/CAPP integrated model of flexible module based on feature and CAD/CAPPmapping model based on process planning match board are set up. The keytechnologies of Solidworks/SmarTeam/CAPP integration are studies.4. From the point of view of process match board and step match board, theprocess of creating to process planning match board is studied. As an example, themachining process planning of up beam of hydraulic press machines is used tointroduce the establishment of process planning match board by means of inferencebased on expert knowledge. The organize model about the process planning matchboard oriented product family is brought forward.5. The multi-decision methods of CAPP system based on analytic hierarchy aregiven.. On the basis of uniform data model, the sub-machining process planning ofpart is auto-created by means of analytic hierarchy, The step decision methods basedon AHP is put forward.6. For the design/manufacture information in the course of product life cycle, thetree structure based on Object-Oriented and static model based UML are founded. Themethod of establishing design/manufacture information management system isbrought forward. The commercial PLM software—SmarTeam is regarded asdevelopment platform, on basis of which, the design/manufacture informationmanagement system is built, and the multi-view mapping technique ofdesign/manufacture information model is studies.7. A computer-aided CAPP platform based on PDM/PLM is founded, and itsstructure, function, work flow is illustrated. Some example of the system areintroduced.

阐述课题提出的目的和意义，明确了本文研究的主要内容。2、提出基于PDM/PLM的制造过程信息化集成模式；在平台式CAPP系统的设计约束模型基础上，构建了平台式CAPP系统的体系结构；并给出工艺决策模型和功能模型；最后提出基于SmarTeam的CAPP开发模式和实现策略。3、建立模块化产品生命周期模型的组织结构；针对面向产品族的广义模块的划分和规划方法，建立基于特征的柔性模块CAD/CAPP集成模型及基于工艺模板的CAD/CAPP映射模型；研究Solidworks/SmarTeam/CAPP集成的关键技术。4、从工序模板和工步模板的角度研究了工艺模板的创建过程；以液压机上梁模块机加工为例，采用基于专家知识的推理技术实现了工艺模板的创成；提出了面向产品族的工艺模板分层结构树的组织模式。5、提出基于分层规划的多模式工艺决策流程；在统一数据模型的基础上，从特征层和零件层分层规划，实现了零件加工子工艺的自动创成；提出基于AHP的工步排序决策方法。6、针对产品生命周期中的设计/制造信息，建立了面向对象的类树结构和基于UML的静态结构模型；提出基于PDM/PLM软件的设计/制造信息管理系统的构建方法；以商品化PLM软件SmarTeam作为开发平台，开发了基于SmarTeam的设计/制造信息管理原型系统；研究设计/制造信息模型多视图映射机制。7、开发了基于PDM/PLM的平台式CAPP原型系统，构建了系统的功能模型，并对系统的主要功能进行说明，给出系统的运行实例。

We present a patient with multiple seborrheic keratosis-like lesions on the trunk with characteristic pathologic findings, which is first reported in Taiwan. The histology showed hyperkeratosis, acanthosis, and papillomatosis accompanied with acantholysis in the superficial epidermis.

我们报告一个病人在躯干有多个类似脂漏性角化症病灶，病理显示角化过度、棘层肥厚、有乳突瘤状增生以及上层表皮有棘层松解，与国外文献报告雷同，然而首次报告於台湾落叶性天庖疮病人。

Hierarchical linear modeling is the most frequently used technique for analyzing multilevel data. In this paper, the twelve key issues in multilevel research and/or using HLM software were reviewed, and provided their exact meanings and feasible solutions. The 12 key issues included intraclass correlation coefficient, sample sizes, formation of organizational constructs, centering problems, fixed effect and random effect, estimation methods, goodness of fit index, explained variation, multicollinearity, robust standard error, level one variance equation, and empirical Bayes estimates.

本文针对阶层线性模式在多层次研究上有关於技术、测量与方法论所遭遇的问题，进行文献整理并讨论其实务意涵，并依据使用时机、抽样议题、资料汇总、分析方法、与模式评估与估算等五方面整理出十二项重要议题与解决之道，包括：组内相关系数的意义与判断准则、多层次研究各层的样本数问题、变数聚合成组织层次问题、中心化的意义、固定效果与随机效果的设定、估计法的选择、适配度的比较、解释变异量的计算、多元共线性的分析、强韧性标准误、第一层误差项变异数与实证贝氏估计值的运用。

Arc-glow plasma depositing technique is a new surface coating method. With the help of vacuum arc discharge, a cold cathode arc source continually emits ion beams of coating elements with high currency density and high ionizing ratio.Upon the ion bombard and diffusion work on, the surfaces of the parts form deposited layers, diffusion layers. In this study, a commercial magnesium alloy AZ91 was coated with Ti film layer.

加弧辉光离子渗镀技术将辉光放电与弧光放电有机地结合起来，利用辉光放电空心阴极效应使工件迅速升温，同时在真空容器壁上设置一个或多个金属阴极电弧靶源，利用真空电弧放电而不断地发射出高能量、高电流密度、高离化率的欲渗金属离子流，依靠扩散和离子轰击作用快速渗入工件表面层，在工件表面可以形成渗层、镀层、渗镀结合层。

The geology research of carbonate reservoirs in Ordovician of Tahe oilfield showed that many large dissolved vugs and fractures were developed. The spread of the reservoir take on a very heterogeneous state. And the typical fractured-vuggy reservoirs was formed. According to the combination of the various spaces, the formation was divided into vuggy formation, fractured-vuggy formation and fractured formation. The research showed that development of the vug is relevant to the its position on the structure, the fractures, the water surface and the weathering surface. Multi-phase charge and recharge of the oil in the reservoirs resulted in the complexity of the fluid distribution. So the"Bottle Model"was brought forward to explain the movement of the water-oil contact. The special storage space and the complex fluid distribution lead to the unstability of the production and the complexity of the water cut. In order to explain the characteristic of the fracture-vug unit was brought forward and the basic principle and method of the partition of the fracture-vug unit was formed. The classification and evaluation of the units were performed according the reserve and energy. Based on the research of geology characteristic and the fluid flow in the reservoir the comprehensive numerical simulation plan of the fractured-vuggy reservoirs were established. Through the selection of the simulation unit, fluid flow type and parameter equivalent the triple media reservoir simulation model was established. Considering the practical application the model was resolved by the DKR decomposition conjugate grads method. Based on the fine reservoir description of Dsitrict IV of the Tahe oilfield the various space type were classified and combined together. The geology model of Unit S48 was constructed. Two typical single well model was established according to the geology and the dynamic phenomena. Finally the single well model and the Unit S48 were simulated by the triple media reservoir simulator. Via the local grid refinement and coarsening in the simulation good matchs were gained. Based on the results of the simulation the reserve distribution, percent of reserve produced in various space and the natural energy were analyzed. The fluid was storaged in the fractures and vugs mostly and more than 90% the produced oil came from the systems. The energy belonged to the active one. The results of simulation accorded with the fact and showed the validity and practicability the research and the simulator.

塔河油田奥陶系碳酸盐岩油藏的地质研究表明，其储层中发育着很多大型的溶蚀洞、缝，储层的平面展布呈现出极度的非均质性，形成了典型的缝洞型碳酸盐岩油藏，根据各种孔隙介质在储层中的组合，将储层分为了溶洞型、裂缝-溶洞型和裂缝型三类；研究表明溶洞储层的发育和构造位置、裂缝的发育、潜水面和风化面的位置等因素有关；多期充注的油气成藏模式导致了流体复杂的赋存状态，由此提出了所谓的"瓶子模型"，解释生产过程中油水界面的变化；特殊的储集空间类型和流体分布特征导致油田在开发过程中表现出很大的不确定性和含水变化的复杂性，为了合理的解释油气田开发过程中的动态特征，提出了"缝洞单元"的概念，并制定了"缝洞单元"纵横向划分的基本原则和依据及划分方法，并对"缝洞单元"进行了分类和评价；基于地质特征和流体在其中流动规律的研究，提出了缝洞型碳酸盐岩油藏的数值模拟综合解决方案，通过模拟单元的选择、流动类型和参数的等效，建立了三重介质油藏三维三相数值模拟模型，采用不完全LU分解预处理共轭梯度法进行了求解；在塔河油田4区精细油藏描述的基础上，将各种类型的孔隙空间进行了归类组合，建立了S48单元的地质模型；通过对油井生产动态进行分析研究，建立了两类和油井地质、生产动态相对应的单井模型；最后应用三重介质油藏数值模拟软件对单井模型和S48单元进行了数值模拟，通过局部加密和粗化等技术模拟流体流动规律，取得了很好的拟合效果；结合数值模拟结果，分析了各种介质中的储量分布、储量产出的百分比以及地层的能量，认为塔河油田缝洞型油藏中流体绝大多数储集于缝洞系统之中，所产出流体90%以上也来自于缝洞系统，其底水能量属于较充足的类型；模拟结果和油田实际情况符合较好，说明了地质研究和油藏数值模拟研究的正确性。

Aimed at these problem, this paper taked 63 well drilling's rock mineral document and logging document as main analysis object, combined reservoir sedimentology, sequence stratigraphy, logging geology together to research sedimentary system, sequence stratigraphy, lithofacies paleographic, sandbody distribution three dimensional visualization, reservoir character and reservoir sandbody comprehensive evaluation, it offers reference and criterion for Changbei gas field gas reservoir's exploration and development.

针对目前所存在的地质问题，本论文以63口钻井的岩矿资料和测井资料为主要分析对象，运用储层沉积学、层序地层学、测井地质学等多学科交叉的综合研究方法，对长北气田上古生界二叠系山西组2段进行沉积体系、层序地层、岩相古地理、砂体展布三维可视化、储层特征以及储集砂体综合评价和有利区预测等方面进行系统和深入的研究，为更有效地勘探开发长北气田提供科学依据。

The geology research of carbonate reservoirs in Ordovician of Tahe oilfield showed that many large dissolved vugs and fractures were developed. The spread of the reservoir take on a very heterogeneous state. And the typical fractured-vuggy reservoirs was formed. According to the combination of the various spaces, the formation was divided into vuggy formation, fractured-vuggy formation and fractured formation. The research showed that development of the vug is relevant to the its position on the structure, the fractures, the water surface and the weathering surface. Multi-phase charge and recharge of the oil in the reservoirs resulted in the complexity of the fluid distribution. So the"Bottle Model"was brought forward to explain the movement of the water-oil contact. The special storage space and the complex fluid distribution lead to the unstability of the production and the complexity of the water cut. In order to explain the characteristic of the fracture-vug unit was brought forward and the basic principle and method of the partition of the fracture-vug unit was formed. The classification and evaluation of the units were performed according the reserve and energy. Based on the research of geology characteristic and the fluid flow in the reservoir the comprehensive numerical simulation plan of the fractured-vuggy reservoirs were established. Through the selection of the simulation unit, fluid flow type and parameter equivalent the triple media reservoir simulation model was established. Considering the practical application the model was resolved by the DKR decomposition conjugate grads method. Based on the fine reservoir description of Dsitrict IV of the Tahe oilfield the various space type were classified and combined together. The geology model of Unit S48 was constructed. Two typical single well model was established according to the geology and the dynamic phenomena. Finally the single well model and the Unit S48 were simulated by the triple media reservoir simulator. Via the local grid refinement and coarsening in the simulation good matchs were gained. Based on the results of the simulation the reserve distribution, percent of reserve produced in various space and the natural energy were analyzed. The fluid was storaged in the fractures and vugs mostly and more than 90% the produced oil came from the systems. The energy belonged to the active one. The results of simulation accorded with the fact and showed the validity and practicability the research and the simulator.

塔河油田奥陶系碳酸盐岩油藏的地质研究表明，其储层中发育着很多大型的溶蚀洞、缝，储层的平面展布呈现出极度的非均质性，形成了典型的缝洞型碳酸盐岩油藏，根据各种孔隙介质在储层中的组合，将储层分为了溶洞型、裂缝-溶洞型和裂缝型三类；研究表明溶洞储层的发育和构造位置、裂缝的发育、潜水面和风化面的位置等因素有关；多期充注的油气成藏模式导致了流体复杂的赋存状态，由此提出了所谓的&瓶子模型&，解释生产过程中油水界面的变化；特殊的储集空间类型和流体分布特征导致油田在开发过程中表现出很大的不确定性和含水变化的复杂性，为了合理的解释油气田开发过程中的动态特征，提出了&缝洞单元&的概念，并制定了&缝洞单元&纵横向划分的基本原则和依据及划分方法，并对&缝洞单元&进行了分类和评价；基于地质特征和流体在其中流动规律的研究，提出了缝洞型碳酸盐岩油藏的数值模拟综合解决方案，通过模拟单元的选择、流动类型和参数的等效，建立了三重介质油藏三维三相数值模拟模型，采用不完全LU分解预处理共轭梯度法进行了求解；在塔河油田4区精细油藏描述的基础上，将各种类型的孔隙空间进行了归类组合，建立了S48单元的地质模型；通过对油井生产动态进行分析研究，建立了两类和油井地质、生产动态相对应的单井模型；最后应用三重介质油藏数值模拟软件对单井模型和S48单元进行了数值模拟，通过局部加密和粗化等技术模拟流体流动规律，取得了很好的拟合效果；结合数值模拟结果，分析了各种介质中的储量分布、储量产出的百分比以及地层的能量，认为塔河油田缝洞型油藏中流体绝大多数储集于缝洞系统之中，所产出流体90%以上也来自于缝洞系统，其底水能量属于较充足的类型；模拟结果和油田实际情况符合较好，说明了地质研究和油藏数值模拟研究的正确性。

This chapter holds that the literary work is the polyphony of the heterogeneous strata, which contains the stratum of phonetic formations, the stratum of semantic units, the stratum of schematized aspects, the stratum of represented objects.

第一章文学作品的多层次构成认为，文学作品是由语音构造层、意义单元层、图式化观相层、被再现的对象层构成的异质复调的整体结构。

To prepare the phosphorylated PRAS40 (Ser183) antibody, We chosen 10-amino acid including Ser183 as antigen peptide through antigenicity and hydrophobicity analysis, hinged on keyhole limpet hemocyanin, and used the KLH-peptide to immunize rabbits. After antibody serum titer detection by enzyme linked immunosorbent assay, the antibody was purified with rProtein A sepharose fast flow and dephosphorylated antigen membrane. The antibody titrate reached 1:10 000 after purification and its special property was enhanced with absorption treatment of dephosphorylated antigen membrane. In addition, we used rabbit anti-PRAS40 antibody and the phosphorylated PRAS40 (Ser183) antibody to detect PRAS40 expression in several cell lines, including the normal cells HL7702, HEK293, tumor cells HepG2, A549 and S180. There were no quite difference among these cells; otherwise, we observed the decreased phosphorylation level of Ser183 after amino acid withdrawal treatment.

为了制备PRAS40(Ser183)磷酸化多克隆抗体，本实验通过蛋白疏水性抗原性分析设计多肽抗原，用其免疫家兔获得抗血清， ELISA检测其效价为1：10 000； Western blotting法检测发现，通过rProtein A Sepharose亲和层析纯化并经非磷酸化的抗原条吸附处理后的抗体可以明显提高磷酸化抗体的特异性；用PRAS40抗体及PRAS40(Ser183)磷酸化抗体对正常细胞HL7702、HEK293及肿瘤细胞HepG2、A549、S180的检测显示：磷酸化的Ser183在不同细胞中表达差异不显著，而在经细胞饥饿处理的HEK293细胞中却明显观察到了S183磷酸化水平随氨基酸含量降低而减弱的现象。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。