多型性

Objective: 1 To study the relationship of type 2 diabetes mellitus and osteoporosis.

目的： 一、探讨2型糖尿病患者骨密度的变化；二、探讨雌激素受体基因多态性与2型糖尿病患者BMD的关系。

Real-time fluorescence quantitative PCR technique has been widely applied, such as mRNA expression, detections of DNA copy number and determination of mononucleotide polymorphism, as well as in the clinical medicine including accurate quantitative examination of mycobacterium tuberculosis, Type B and Type C hepatitis, AIDS virus, gonococcus, and chlamydia trachomatis.

实时荧光定量PCR的应用范围非常广泛，包括mRNA表达的研究、DNA拷贝数的检测、单核苷酸多态性的测定等，已广泛应用于医学临床，它能对结核分枝杆菌、乙型、丙型肝炎、爱滋病病毒、淋球菌、沙眼衣原体等病原体进行准确的定量检测。

The international master swimmers are very special group because of the high frequency of VDR gene polymorphisms.

(1)不同运动水平运动员VDR基因该位点多态性分布具有一定的差异，运动水平越高的运动员群体其 AG基因型分布频率越高，提示不同基因型运动员对运动训练的敏感性可能不同。

The amplified porducts of AY204223 exhibited polymorphism in wild swordtails, and displayed different band patterns among the three inbred Xiphophorus helleri.

结果 有4对引物可扩增出稳定条带，1对引物(AY204223)的PCR扩增条带在非选育群中表现多态性，在RR-B与BY-F系表型一致，与RW-H表型不同。

In the progress of tumor development, it shows heterology, and formed different subgroup, promote metastasis.

其表现为肿瘤在组织形态学、核型，免疫表型，遗传标志物，生长率，细胞产物，药物敏感性以及其他细胞组织学特征方面呈现广泛的多态性，从而产生不同转移能力的癌细胞。

Results Among 54 WD patients, 36 were found to carry Arg778leu mutation, among whom 15 were homozygote, 21 were heterozygote, the frequency of this mutation was 47.2%. Of 46 patients with hepatic damage, 36 were found to have the mutation of Arg778Leu, among whom 34 were found to have Leu770Leu polymorphism simultaneously.

结果 54例Wilson病患者中36例存在Arg778Leu基因突变，15例为纯合型，21例为杂合型，Arg778Leu等位基因突变频率为47.2 ％；46例伴肝损害的患者中33例存在ATP7B基因外显子8的Arg778Leu突变；36例Arg778Leu突变者中34例同时伴有Leu770Leu多态性。

There was a higher integral of metastasis in E4 genotype group than others, and a lower integral of metastasis in E2 genotype group than others, Multiple regression analysis showed that genotypes were significantly associated with the TC TG HDL levels and integral of metastasis.

ApoE基因多态性对血脂具有显著影响，E3/3基因型的HDL水平明显高于E2基因携带者，且基因型与TC浓度、TG浓度、HDL浓度明显相关。

In chapter 4, in the frame of partially ordered F-type topological space, we research the existence of the solution of a nonlinear operator equation Lx = Nx, and the convergence of the iterative sequence {u_n} which satisfies Lu_(n+1)= Nu_n for a solution of the equation. Then, we give the conditions for multiplicity of the solutions of this operator equation.

第四章，在半序F-型拓扑空间框架下研究一类非线性算子方程Lx=Nx解的存在性，以及满足Lu_(n+1)=Nu_n的迭代序列{u_n}对于方程解的收敛性，并给出这类算子方程具有多解性的条件。

Seven main effect QTLs and 7 digenic interactions controlling heat tolerance during flowering time were detected in two-year experiments.

利用181个在亲本间具有多态性的SSR标记，构建了覆盖水稻全基因组1559.6cM、标记间平均距离为8.3cM的遗传连锁图谱。2年共检测到7个抽穗开花期耐热性主效应QTL以及7对上位性QTL.2004和2005年分别检测到3个和4个QTL，共解释29%和37.3%的表型变异。

Super large type sedimentary hydrothermal sulfide ore deposits, located in middle Qinling and west Yinshan mountains, has shown the multi metal and pyrite type deposit The deposits are shown sililay geo geochemistry characteristics to SEDEX sulfide deposits in middle Proterozoic and Paleeozoic Era in the world, i e , ore forming age were 1 4～1 2 Ga and 0 4～0 3 Ga ore bodies show more than 1 000 m long and multi layered distribution, the ore of sulfide rich show massive band...

地质地球化学特征与世界中元古界和古生界中的SEDEX 硫化物矿床基本相同：成矿时代为1－4 ～1－2 Ga 和0－4 ～0－3 Ga，均产于克拉通边缘盆地中；矿体延长达千米以上，具多层性特征；富硫化物矿石为块状条带状，矿物组合简单，有显著分带性；硫同位素组成为海相硫酸盐型，铅同位素为混合程度较高的均匀性铅等。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。