多型性

As part of the Stroke Prevention in Young Women study, which is evaluating genetic and nongenetic ischemic stroke risk factors in young women, the investigators systematically searched the PDE4D gene for novel and known polymorphisms in 48 African-American women and 48 white women. These polymorphisms were then prioritized and genotyped in the entire study population of 224 cases of first ischemic stroke and 211 age- and race-matched controls.

年轻妇女中风预防研究里面的一部分，评估年轻妇女基因性和非基因性缺血性中风风险因子，研究者系统式蒐寻48位非裔美籍妇女和 48位白种妇女之PDE4D基因之新的和已知的多型体，这些多型体按基因型顺序排好，400位之中有224例首次缺血性中风，有211位是年纪和种族配对控制组。

The phenotype values of the major gene and polygene mixed inheritance of quantitative trait demonstrate multimodality, showing the mixture of more than one normal distributions, that is corresponding to more than one major gene genotypes, so the selection is different from common quantitative trait in model hypothesis and analysis.

主基因-多基因混合遗传的数量性状，其表型值呈现多峰性，表现为多个正态分布的混合，即对应多个主基因基因型，其选择与普通数量性状的选择在模型假定以及分析上都有很大的不同。

The phenomenon of polyploidy and aneuploidy exists in the Genus, in which there are polyploid complex.

对19个分类群作了核型观察，其中16个分类群作了组型分析，结果表明各分类群间核型差异显著，该属普遍存在着多倍性和非整倍性现象，并有多倍体复合体类群存在。

B-type was the main serotype of Pasteurella isolated from Zebra, Sambar and White-lipped deer. A-type was the main serotype of Pasteurella isolated from Red Kangaroo.

其中荚膜B型是斑马、黑鹿和白唇鹿源多杀性巴氏杆菌的主要血清群，荚膜A型是赤大袋鼠源多杀性巴氏杆菌的主要血清群。

Aim To establish the method of detecting the Arylamine N-acetyltransferase-1(NAT1) genotype and its distribution of polymorphism,and analyze the correlation between the genotype and the phenotype in a Chinese Hans population.

目的探讨汉族人群中N-乙酰基转移酶1(NAT1)基因多态性的分布特点，以及基因型和表型之间的相关分析，以评价NAT1乙酰化代谢多态性对5氨-基水杨酸等药物疗效的影响。

1Livestock Research Institute, Council of Agriculture(2)Department of Animal Science, National Pingtung University of Science and TechnologyGenetic variation in the N-acetylglucosamine 6-sulfatase (G6S) gene is the key role in caprine Mucopolysaccharidosis IIID.

本研究建立山羊黏多醣症遗传缺陷之单股构型多态性基因型检测方法，应用此方法来检测乙醯醣胺氨基硫酸酶(N-acetylglucosamine 6-sulfatase， G6S)基因型不再需要使用限制酶，可节省检测时间、成本与人力。G6S基因的遗传变异在山羊黏多醣症第三型扮演重要的角色。

Methods 209 patients with CHD and 101 controls were selected. MTHFR genetic C677T polymorphism was determined by PCR-RFLP, and CBS T833C polymorphism by ARMS method. Plasma homocysteine levels were detected with HPLC. Results The frequencies of MTHFR T homogenetic type and heterogenetic type (27.8%and 45.4%) in case group were higher than those in normal group(22.8%and 34.6%).

对209例冠心病患者和101例健康对照者，采用多聚酶链反应-限制性内切酶片段长度多态性技术检测MTHFRC677T基因型，用扩增阻滞突变体系法检测CBS基因T833C多态性，采用高压液相色谱法测定同型半胱氨酸血浆水平。

Methods 202 kinless subjects of the Chinese Han were investigated in this study, including 82 normal controls, and 120 cases diagnosed as CHD. The PPARδ+294T/C gene polymorphism was determined by polymerase chain reaction and restriction fragment length polymorphisms. The frequencies of PPARδ+294T/C genotypes and the "C"allele frequency were analyzed, to evaluate the risk for the CHD among variant genotypes.

运用聚合酶链式反应及限制酶片段长度多态性技术分析无血缘关系汉族人群[包括82例正常对照者，120 例冠心病患者]的PPARδ+294T/C基因多态性，分析基因型频率、等位基因频率，并对不同基因型患者冠心病的危险性进行评价。

This study investigated gene polymorphism of β_1-AR, CY2PD6, ACE and of BDKRB2 in the population of Hunan mid-region by PCR and PCR-RFLP method. The results showed that the frequencies of Ser49Ser and Arg389Arg genotype of β_1-AR gene were respectively 68.7% and 55.3%. And the allele frequencies of 49Ser and 49Gly were 83.9% and 16.1%, moreover 76.1% for 389Arg and 23.9% for 389Gly.

本研究应用PCR、PCR-RFLP方法首次对湖南中部地区403例原发性高血压患者的β_1-AR基因、CY2PD6基因、ACE和BDKRB2基因多态性的调查，结果显示：β_1-AR基因型Ser49Ser、Arg389Arg分别占68.7％、55.3％，49Ser和49Gly等位基因频率分别为83.9％、16.1％，389Arg和389Gly等位基因频率分别为76.1％、23.9％；CYP2D6等位基因频率由高到低依次为~*10、~*1、~*2、~*5，CYP2D6~*10~*10基因型频率最高，占47.4％；ACEI和D等位基因频率分别为55.8％、44.2％，基因型频率分别为Ⅱ型33.5％、ID型44.7％、DD型21.8％；BDKRB2-58T/C等位基因频率C、T分别为52.6％、47.4％，基因型频率分别为CC型24.8％、CT型55.6％、TT型19.6％。

The individuals carrying the IL1RN*2 allele have a lower circulating level of IL-1ra in response to inflammation thereby inducing an increased activity of IL-1 which could be responsible for trigging the development of clinical manifestation in IgA nephropathy and Henoch-Schonlein nephritis.

为了进一步揭示IL-1ra基因多态性与其表型之间联系的本质，在本研究中我们对IL-1ra不同基因型IgAN和HSPN患者外周血单核细胞在炎症因子刺激下IL-1ra的产生能力进行了研究，以期阐明IL-1ra基因多态性对其功能的影响。

The X-ray diffract was used to analyze the crystal structure of the composite. Results show that after the talc was treated with blend coupling agent, the crystal structure of talc changed, and effect Intercalation phenomenon.

通过X射线衍射分析可知，用混合偶联剂对滑石粉进行预处理后，滑石粉晶体结构发生改变，产生了插层现象，使PP／滑石粉复合材料为纳米复合材料。

An authentic Maui wedding might require the services of a 'kahu', which is a Hawaiian minister.

毛伊可能需要一个真实婚礼服务'kahu'，这是夏威夷部长。