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Positive association were still remained for two locus that MNAT1-rs973063 and PCNA-rs25406 and lung cancer risk even after 1000 times permutation test.During the stratified analysis,we revealed that that several genes in the NER pathway could interact with age,gender,family cancer history and smoking status.

在进行了多重校正后,有两个位点仍显示出关联显著性:MNAT1-rs973063(p=0.02),PCNA-rs25406(p=0.03);在随后进行的分层分析中,我们发现NER通路多个基因分别和年龄、性别、肿瘤家族史以及吸烟状况之间存在互作,提示该通路基因位点可能主要是通过和环境交互作用产生效应;我们还进行了单倍型的分析,结果发现PCNA和RPA1两个基因上的单倍型和肺癌易感性相关。

Mucopolysaccharidosis type I is an inborn error of metabolism with progressive multisystem involvement. Hurler syndrome is the most severe form of MPS-I that causes progressive deterioration of the central nervous system with ensuing death.

目的:粘多糖病I型是一种进行性多器官受累的遗传代谢性疾病,Hurler综合征是粘多糖病I型的最严重类型,常导致进行性的中枢神经系统受损和早期死亡。

These results suggest that TNF-alpha may contribute to morbidity during H5N1 influenza virus infection, while IL-1 may be important for effective virus clearance in nonlethal H5N1 disease.

这些结果显示:TNF-alpha可能对H5N1型流感病毒感染的发病起作用,而IL-1可能对非致命性的H5N1型病毒的清除有重要的影响。以上是我的翻译,其中有1000只小鼠的问题,我觉得太多了。是不是我理解错了啊?

Results:Main imaging features of APK were as follows:On abdominal plain films showed the lobalate renal enlargement in 46 cases,calcification of polycystic wall in 14 cases,renal calcium milk in 5 cases,60 cases were showed separation,deform and longthend of renal pelvis on intravenous urography and retrograde urography,5 cases were showed renal enlargement on retroperitoneal pneumography,on CT scans in 25 cases showed mulltiply cysts with thin wall,unecho liquid shadows were showed on B-mode ultrasound.

结果:成人多囊肾的主要影像学征象:腹部平片(46例)显示肾影呈分叶状增大;囊壁钙化(14例);多囊肾合并肾钙乳(5例);肾盂造影(60例),表现为肾盂、肾盏相互分离、变形、拉长;腹膜后充气造影(5例):表现为肾影增大肾影与邻近器官之间的关系,其界限清晰可辨;CT扫描(25例):表现为肾内多数大小不等的薄壁圆形低密度区;B型超声(47例)表现为肾内多个类圆形无回声的液性暗区。

Chronic Hepatitis B is a frequent infectious disease due to HBV clinic, mostly is liver of inflammation and histology and biochemistry, with unconventionality symptom continuous preponderate over six months, state of an illness without looking up or liver have activity variety of inflammation.

慢性乙型肝炎是由乙型肝炎病毒引起的临床上常见传染病,主要是指肝脏的炎症、组织学、生物化学异常征象持续超过6个月,病情无好转或肝内有活动性炎症变化者。把中医辩证和现代检测指标相结合进行研究的报道还不多见。

Histopathologic examination demostrated cystic necrosis in 6 patients, mult ilocular cysticrenal cell carcinoma in 3, and unilocular cystic renal cell carcinoma in 3 patients. 11 patients have been followed up.l patient died of the disease at 9 months. 10 patients had no evidence of disease,whose suvival periods ranged 10 months to 10 years with an average of 3.5 years.

其中肾细胞癌囊性坏死型6例,单房囊肿性肾细胞癌3例,多房囊肿性肾细胞癌3例。11例获随访,其中1例以颅骨转移为首发症状者术后9个月死于肿瘤转移;10例存活至今,存活时间10个月—10年,平均3.5年。

Results The main imaging of adult polycystic kidney disease signs: abdominal plain film (45 cases) showed renal shadow was lobulated increase; cystic wall calcification (14 cases); polycystic kidney disease and renal milk of calcium (8 cases); pelvis angiography (61 cases), the performance of the renal pelvis, renal calices separated, distorted, elongated; retroperitoneal inflatable angiography (6 cases): Performance increases of renal kidney shadow Shadow and the relationship between the neighboring organs, its boundaries clear and identified; CT scan (30 cases): the performance of the majority of the size of the renal low-density areas, ranging from thin-walled circular; B-mode ultrasonography (47 cases) showed a circular echo-free renal multiple classes of liquid dark area .

结果 成人多囊肾的主要影像学征象:腹部平片(45 例)显示肾影呈分叶状增大;囊壁钙化(14例);多囊肾合并肾钙乳(8例);肾盂造影(61例),表现为肾盂、肾盏相互分离、变形、拉长;腹膜后充气造影(6例):表现为肾影增大肾影与邻近器官之间的关系,其界限清晰可辨;CT扫描(30例):表现为肾内多数大小不等的薄壁圆形低密度区;B型超声(47例)表现为肾内多个类圆形无回声的液性暗区。结论影像学检查有助于提高多囊肾的诊断的准确性。

Psoriasis vulgaris damage is much more varied, and some rash was known as the teardrop-shaped for squamous guttate psoriasis; small scales damages in the pilosebaceous openings, known as the hair follicles of psoriasis; if scaling was called rupioides rupioides psoriasis; some damage was irregular map-like, called the map-like psoriasis; clinically the most common damage is discoid or coin-like, called discoid or coin-like psoriasis.

寻常型牛皮癣的损害变化较多,有的皮疹呈为鳞屑性水滴状称为点滴状牛皮癣;细小鳞屑性损害位于毛囊皮脂腺开口,称为毛囊性牛皮癣;如果鳞屑呈蛎壳状称为蛎壳状牛皮癣;有的损害不规则呈地图状,称为图状牛皮癣;临床上最常见的损害是盘状或钱币状,称为盘状或钱币状牛皮癣。

The result of homological analysis showed that an open reading frame,which contains 289 amino acids,is more similar to the Choristioneure fu- m...

比较多种核型多角体病毒的多角体膜蛋白和多角体蛋白的氨基酸序列发现,这两种多角体结构蛋白的同源性具有相似的变化趋势。

Methods Polymerise chain reaction and restriction fragment length polymorphism were used to analyze the polymorphisms of MTHFR genes C6677T and A1298C in 56 patients of colorectal cancer and 143 age-and-sex-matched control subjects.

方法以聚合酶链反应和限制性片段长度多态方法,对56例直肠癌患者和143例正常人对照的MTHFR基因C677T和A1298C基因型进行检测分析其对直肠癌风险的相关性。结果在正常对照组中,MTHFRC677TCC、CT、TT基因型频率分别为62·90%、35·08%和2·12%,而在直肠癌病人中分别为58·93%、26·77%和14·26%。A1298C与A1298C基因型在病例和对照中的分布差异无显著性意义。

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