多型性

THE CORRELATION BETWEEN POLYMORPHISM OF ALDOSE REDUCTASE GENE AND DIABETIC NEPHROPATHYCHEN WEN HUADepartment of Geratology, The Affiliated Hospital of Yanbian University, Yanji 133000, China

摘要］ ①目的探讨染色体7q35区醛糖还原酶基因启动子区C 106T多态性与2型糖尿病肾病相关性。

The homozygote of MTHFR C677T may be an important risk factor of AMVT.

MTHFR C677T多态性中TT基因型可能是AMVT形成的一个重要遗传风险因子。

These variations may have some effect on gene structures and gene expression, and then contribute to intraspecific phenotypic diversities.

在物理图提供的序列基础上，对于籼粳稻两个主要栽培稻亚种进行了比较基因组分析，在2.3Mb对应区段中发现了两个亚种在基因组成和顺序上存在的广泛的微共线性，两者之间的差异主要由插入/缺失和单核苷酸多态性造成，这些差异可能影响基因的结构和表达，从而对种间表型差异产生影响。

Interleukin-10; Single nucleotide poly- morphism ; Hepatitis B virus

白细胞介素-10；单核苷酸多态性；乙型肝炎病毒

There were significant multipliable interaction among genotype A/A and Psychoticism, Introverts, low- Positive coping style, the γ value were respectively 2.528,1.878,1.935; There were positive additive interaction between genotype A/A and Neuroticism, the γ value was 1.032; There were negative additive interaction between genotype A/A and LES, the γ value was 0.791; There were no significant interaction among genotype A/A and Negative coping style, low-social support.

NET基因多态性G1287A与社会心理学因素交互作用与MD的关联研究：G1287A AA基因型与精神质人格、内向型人格及较少采取积极应对方式可能存在超相乘模型交互作用，γ分别为2.528，1.878，1.935；与神经质人格可能存在正相加模型交互作用，γ为1.032；与生活事件可能存在夫相加模型交互作用，γ为0.791；与消极应对方式、社会支持可能不存在交互作用。

Some of the laryngeal MFH were difficult to be differentiated from carcinosarcoma, pleomorphic rhabdomyosarcoma , myxoid liposarcoma ,malignant neurilemmoma and myxoma without immunohistochemical aids .

喉恶性纤维组织细胞瘤常规组织学与癌肉瘤、多形性横纹肌肉瘤、粘液型脂肪肉瘤、恶性神经鞘瘤、粘液瘤有时易混淆，免疫组织化学有助于明确诊断。

Methods: Among Chinese people of Han nationality in Nanjing,119 patients with type 2 diabetes mellitus and 116 nondiabetic subjects were collected randomly.

目的： 探讨南京地区汉族人群中对氧磷酶1基因（PON1）多态性与2型糖尿病是否存在相关性。

Methods: Genotypes of E-selectin were analyzed in 135 angina pectoris and 145 normal controls by polymerase chain reaction-restriction fragment length polymorphism. Plasma lipid levels were measured by biochemical technology.

应用聚合酶链反应-限制性片段长度多态性技术检测135例心绞痛患者和145例正常对照者E-selectin基因型，生化技术测定血脂水平。

Objective:To understand the neutrophil antigen gene polymorphism in the Hui nationality in North west China by typing of NA gene.

目的：通过NA基因分型，了解中国西北地区回族人群NA基因多态性。

Domenstic and abroad academicians have disclosed the influence mechanism of these factors from different aspects, including the gene polymorphism and gene mutation in genetics, which are a susceptible factor for cardiovascular complication in type 2 diabetes patients; the dysfunction of endotheliocyte, the metabolic disorder of lipid, and dysfunction of vascular smooth muscle, which can lead to the formation of arteriosclerosis;the formation of immune complex,which can also accelerate the destruction of artery paries;the sctivation of protein kinase C and the dysfunction of platelet, which may ultimately result in the formation of thrombus and influence the function of cadiac muscle cells.

其中主要包括：遗传学方面的基因多态性和基因突变，二者均是2型糖尿病合并心血管疾病的一个易感因素，内皮细胞功能障碍、脂质代谢异常及血管平滑肌细胞功能异常均可导致动脉粥样硬化的形成；免疫复合物的形成可加速动脉壁的破坏；蛋白激酶C的激活及血小板功能受损最终导致血栓形成并影响心肌细胞的功能。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。