多型性

In Chapter 4, we consider the qusilinear elliptic systems with the homogeneous Neumann boundary condition, and obtain the existence and multiplicity of positive solutions.

在第四章中，我们讨论带有齐次Neumann边界条件的拟线性椭圆型方程组(方程和第三章的一样，边界条件不同)，研究了正解的存在性和多解性。

Most of them are low grade or well differentiated liposarcoma (rather than the myxoid or pleomorphic variants of liposarcomas).

大部分都属于低级别或分化良好型脂肪肉瘤（而非粘液型或多形性脂肪肉瘤）。

The rates of nonsynonymous substitutions occurred at a significantly lower frequency than that of synonymous substitutions, which were not consistent with the common rule.

在这些扬子鳄样本中共检测到34个单倍型，每个亚种群内检测到的单倍型数量分别为15，9和10个，与其他一些动物如哺乳动物和鲤科鱼类相比，扬子鳄MHC Ⅱ类B基因第3外元多态性较高。

The chromatin unfolding assay showed that ,like the wild-type transactivation domain, two variants that represent benign polymorphisms did not induce chromatin unfolding or only induced subtle change. Contrary to the behaviors of the wild type and two benign variants, four cancer-predisposing mutations in the transactivation domain superactivate the chromatin unfolding. The results suggest that the chromatin unfolding assay can aid in the characterization of deleterious mutations in the C-terminal transactivation domain of BRCA1 and may provide more reliable presymptomatic risk assessment.

对这些重组质粒的染色质伸展活性检测表明，野生型pwt和两种良性多态性突变体不具有染色质伸展活性或只有极微弱的染色质伸展活性，而其他4种乳腺癌易感突变体均具有过强的染色质伸展活性，提示利用染色质伸展技术可预测BRCA1转录激活区基因型与乳腺癌发生风险的表现型的关系。

Methods The method of PCR- RFLP was conducted to examine the genotype of 3 cPLA2 genes ( PLA2G4A, PLA2G4B and PLA2G4C genes) in 263 subjects, including 121 cases of T2DM and 142 controls. The conditional test was used to test the combined effect of distinct loci on the T2DM by conditioning on allele or by conditioning on genotype with UNPHASED analysis platform. Results The genotypic frequencies of the 3 genes did not deviate from Hardy-weinberg equilibrium in both case and control groups.

采用聚合酶链反应-限制性内切酶片段长度多态性方法检测T2DM患者（病例组121例）和健康对照（对照组142例）3个cPLA2基因（PLA2G4A、PLA2G4B和PLA2G4C基因）的基因型；借助UNPHASED分析平台，利用等位基因条件分析和基因型条件分析方法分析基因的联合作用与T2DM的遗传相关性。

These data indicate a high level of genetic diversity in the Yarkand hare.

全部样品中定义了19个单倍型，每个种群都显示了很高的单倍型多态性。

This thesis gave a study on the polymorphism of ob gene in erhualian, xiang pig, Large White, Duroc, Landrace, Pietran and Landrace X erhualian crossbreeds , by means of Bi-PASA.

本文采用Bi-PASA方法对二花脸、香猪、大约克、杜洛克、长白、皮特兰和苏钟1系猪七个类型，共计420头猪的DNA样进行了OB基因的分型研究，分析了各基因型之间在产仔数性状和生长性状上的差异，以及各个品种类型在该位点的多态性。

The materials with Wx^1 genotype and G-type of Wx gene had higher AC and harder GC, however, the materials with Wx^2,Wx^3 genotypes and T-type of Wx gene had lower AC and sof- ter GC.

利用484／485引物检测，Wx基因呈Wx^1、Wx^2和Wx^3种多态性；而用PCR-Acc I检测，Wx基因表现为G型和T-型。

Polymorphism of HLA-DQB1 promoter region in Hans IDDM patients and normal controls have been identified by PCR, PCR/SSCP and PCR/sequencing methods.No differences were found in y and s box between patients and controls carrying different allele as well as in different ethnic groups. There are two different sequences in x box,but CCTAGAGACAGATT sequence locates frequently on the haplotype with DQB1.0302 allele. Polymorphism between transcription point and y box (at position －44～-46 and －59～-61) might be associated with the genetic susceptibility to IDDM. Additionally,a new single base mutant (CACC→CAC A ) was found at position －131 and －128 in two patients carrying DQB1.0601 allele.

结果显示携带不同等位基因的患者与对照者DQB1 5'-调控区y、s box核苷酸序列相同，且与白种人基因结构一致；y box核苷酸序列存在二种结构，CCTAGAGACAGATT序列常常与DQB1.0302等位基因在同一单倍型；转录起始位点至y box间-44至-61位存在多态性，-59至-61位AAG等位基因可能与1-型糖尿病易感相关联；在2例携带DQB1.0601等位基因患者的-131至-128位间发现CACC→ACA A单个碱基取代突变。

Genotype BB-representing Arg 669 was well-conserved amino acid with other MC4R subtypes or other species MC4R.

这个突变位于5′-调控区上，对该位点的多态性与肉用性状关系分析，发现突变基因型BB个体的腿肌重显著高于野生型AA个体（P＜0.05）。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。