多周期的

Access to a large number of Chinese and foreign literatures, this text summarized the life cycle of aphids including anholocyclic type, heteroecious holocyclic type and antoecious holocyclic type, and the important biological characteristics including alternation of generations, difference of hibernation and polymorphism, it offered the theory basic of comprehensive prevention and control.

通过查阅大量的中外文献，对蚜虫生活周期的不全周期生活史、全周期同寄主生活史和全周期异寄主生活史进行了阐述，归纳出蚜虫生活周期中的世代交替、越冬方式的差异、多型现象几个主要生物学特点，为蚜虫的科学控制提供一定的参考价值。

Disclosed is a leaky-wave dual polarized slot type antenna, including: first and second feeding circuit sections comprised of N-first strip lines and N-second strip lines with a loop every first period along the X-axis on the first dielectric layer and a second period along the Y-axis, in which the N-first strip lines and the N-second strip lines are parallel to each other being alternate, and each length of Ls1 and Ls2 for the first period satisfies the equation of , first and second multi-channel dividers formed at once and the other sides of the first dielectric layer, to connect the N-first strip lines and the N-second strip lines parallel with each other; and first and second central ports formed in the opposite direction of the cavity, each of the feeding circuit sections being connected to the first and second multi-channel dividers; and first and second slot sections being formed by patterning the second shielding layer, in which M-first and M-second slots are arrayed along the direction of the X-axis and each of the first and second slots forms N-row first and N-row second slot arrays, respectively, which cross the first and second strip lines for each, the first slot and the second slot being orthogonal to each other.

公开了一种漏泄波双偏振槽型天线，包括：第一和第二馈电回路部分，其具有沿着X轴在第一介电层每第一周期以及沿着Y轴的第二周期形成具有环路的N第一带状线和N第二带状线，其中N第一带状线和N第二带状线彼此平行并交替，并且对第一周期的各Ls1和Ls2的长度满足等式，第一和第二多通道分配器寻形成在第一介电层的一侧和另外一侧上，以连接彼此平行的N第一带状线和N第二带状线；以及形成在腔的相对方向中的第一和第二中心端口，每个馈电回路部分连接到第一和第二多通道分配器；以及第一和第二槽部分，所述第一和第二槽部分通过对第二屏蔽层形成模式而形成，其中M第一和M第二槽沿着X轴的方向安置，各第一和第二槽分别形成N行第一和N行第二槽阵列，其对每个横过第一和第二带状线，第一槽和第二槽彼此正交。

In addition, an experimental system using C language is established, including modules such as representation of waveform polynomial, decision of path senstization, delay computing, clocking based on single-period sensitization, clocking based on multi-period sensitization, test generation considering noise and transformation from bit-level waveform polynomial to word-level polynomial model. They respectively used to test models and techniques proposed in this paper.

另外，：基于C语言本人设计开发了一个实验软件系统，该系统包括波形多J一贞式表示模块、敏化通路判定模块、延时计算模块、单周期敏化的最小时钟周期精确确定模块、多周期敏化的最小时钟周期确定方法模块、考虑噪声的测试生成模块和位级波形多项式描述转化成字级多项式描述模块，分别用于对本文各章中提出的自动化设计的模型和方法进行实验验证。

A new method that transforms bitlevel waveform polynomial to word-level polynomial model is given, allowing for simple composition This method offers an efficient way to determine whether two descriptions from different design levels are equivalent, so component reuse, synthesis and verification across design levels can be realized. In addition, an experimental system using C language is established, including modules such as representation of waveform polynomial, decision of path senstization, delay computing, clocking based on single-period sensitization, clocking based on multi-period sensitization, test generation considering noise and transformation from bit-level waveform polynomial to word-level polynomial model. They respectively used to test models and techniques proposed in this paper.

另外，基于C语言本人设计开发了一个实验软件系统，该系统包括波形多项式表示模块、敏化通路判定模块、延时计算模块、单周期敏化的最小时钟周期精确确定模块、多周期敏化的最小时钟周期确定方法模块、考虑噪声的测试生成模块和位级波形多项式描述转化成字级多项式描述模块，分别用于对本文各章中提出的自动化设计的模型和方法进行实验验证。

The stable clones are further identified by RT-PCR and Western blot; 6 MTT assay is used to investigate the effect of ZNRD1 on the cell growth of cells (AGS, SGC7901, MKN28, NIH3T3, GES-1); 7 Soft agar assay is used to investigate the effect of ZNRD1 on the clonality of cells (AGS, MKN28); 8 Nude mice assay is used to investigate the effect of ZNRD1 on the cell growth of gastric cancer cells (AGS, MKN28); 9 Flow cytometry is used to investigate the effect of ZNRD1 on the cell cycle distribution of cells (AGS, MKN28, NIH3T3, GES-1); 10 Flow cytometry is used to investigate the effect of ZNRD1 on the cell apoptosis of cells (AGS, MKN28, NIH3T3); 11 MTT assay is used to investigate the effect of ZNRD1 on the drug sensitivity of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR) in vitro; 12 SRCA is used to investigate the effect of ZNRD1 on the drug sensitivity of gastric cancer cells (SGC7901, SGC7901/VCR) in vivo; 13 Flow cytometry is used to investigate the effect of ZNRD1 on adriamycin accumulation of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR); 14 Transmission electron microscope is used to investigate the effect of ZNRD1 on the sensitivity of SGC7901 cells towards drug-induced apoptosis; 15 Flow cytometry and DNA ladder assay are used to investigate the effect of ZNRD1 on the sensitivity of cells (SGC7901, SGC7901/VCR, HL-60/VCR) towards drug-induced apoptosis; 16 Microarray is used to investigate the profiling of ZNRD1-responsive genes in gastric cancer cells (AGS, MKN28, SGC7901, SGC7901/VCR); 17 RT-PCR and Western blot are used to identify the results of microarray; 18 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of cyclin D1; 19 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of MDR1; 20 Kinase assay is used to investigate the effect of ZNRD1 on the activity of cyclin E-CDK2 kinase; 21 The antisensenucleic acids of p21 is used to inhibit the expression of p21, and flow cytometry is used to investigate the effect of p21 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 22 The antisensenucleic acids of p27 is used to inhibit the expression of p27, and flow cytometry is used to investigate the effect of p27 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 23 Liposome is used to up-regulate the expression of Skp2, and flow cytometry is used to investigate the effect of Skp2 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 24 Western blot is used to investigate the effect of ZNRD1 on the stability of Skp2 and p27 in gastric cancer cells; 25 MVD assay is used to investigate the effect of ZNRD1 on the angiopoietic activity of gastric cancer cells; 26 ELISA is used to investigate the effect of ZNRD1 on the expression of VEGF165 in gastric cancer cells; 27 The roles of DARPP-32 in MDR of gastric cancer cells are investigated using gene transfection, MTT assay, SRCA, flow cytometry and DNA ladder assay.

应用杂交瘤技术制备ZNRD1的首个单克隆抗体；2）利用RT-PCR、Western blot和免疫组化检测ZNRD1在胃癌组织、胃炎组织、正常胃上皮组织、胃癌细胞和正常胃组织上皮细胞中的表达；3）构建ZNRD1的小干扰RNA载体，并测序鉴定；4）利用脂质体将ZNRD1的真核表达载体及其空载体转染胃癌细胞（AGS、SGC7901、MKN28）和小鼠成纤维细胞（NIH3T3），G418筛选后进行鉴定；5）利用脂质体将ZNRD1的小干扰RNA载体及其空载体转染药敏胃癌细胞（SGC7901）、正常胃组织上皮细胞（GES-1）、对长春新碱耐药的胃癌细胞（SGC7901/VCR）、药敏白血病细胞（HL-60）、对长春新碱耐药的白血病细胞（HL-60/VCR），G418筛选后进行鉴定；6）利用MTT实验检测ZNRD1高/低表达对细胞（AGS、SGC7901、MKN28、NIH3T3、GES-1）生长的影响；7）通过软琼脂克隆形成实验检测上调ZNRD1对AGS、MKN28细胞克隆形成能力的影响；8）通过裸鼠成瘤实验检测上调ZNRD1对AGS、MKN28细胞体内成瘤性的影响；9）通过流式细胞仪分析ZNRD1高/低表达对细胞（AGS、MKN28、NIH3T3、GES-1）的细胞周期的影响；10）通过流式细胞仪分析上调ZNRD1对细胞（AGS、MKN28、NIH3T3）的凋亡的影响；11）通过MTT实验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）体外药物敏感性的影响；12）通过肾包膜下移植法检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR）体内药物敏感性的影响；13）通过流式细胞仪分析ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）内阿霉素蓄积和泵出的影响；14）通过透射电镜检测上调ZNRD1对SGC7901细胞凋亡敏感性的影响；15）通过流式细胞仪和DNA梯度试验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60）凋亡敏感性的影响；16）通过基因芯片检测ZNRD1高/低表达对胃癌细胞内基因表达谱的影响；17）利用RT-PCR、Western blot对基因芯片的结果进行鉴定；18）利用报告基因实验检测ZNRD1对cyclin D1的启动子活性的调节作用；19）利用报告基因实验检测ZNRD1高/低表达对MDR1的启动子活性的调节作用；20）利用激酶试验检测ZNRD1对cyclin E-CDK2 激酶活力的影响；21）利用反义核酸技术抑制p21的表达；通过流式细胞仪检测抑制p21对ZNRD1介导的细胞周期阻滞的影响；22）利用反义核酸技术抑制p27的表达；通过流式细胞仪检测抑制p27对ZNRD1介导的细胞周期阻滞的影响；23）利用脂质体转染法上调Skp2的表达；通过流式细胞仪检测上调Skp2对ZNRD1介导的细胞周期阻滞的影响；24）利用Western blot检测ZNRD1对p27和Skp2的蛋白稳定性的影响；25）利用微血管密度实验检测ZNRD1对AGS、MKN28细胞裸鼠移植瘤微血管形成的影响；26）利用ELISA检测ZNRD1对AGS、MKN28细胞培养上清和移植瘤匀浆中VEGF165含量的影响；27）利用脂质体转染法、MTT实验、肾包膜下移植法、流式细胞仪和DNA梯度试验检测新耐药相关分子DARPP-32对细胞（SGC7901、SGC7901/VCR、对阿霉素耐药的胃癌细胞SGC7901/ADR）多药耐药表型的影响；利用脂质体转染法和MTT实验检测下调ZNRD1对DARPP-32介导的胃癌多药耐药的调控作用。

In this paper,we study the period of the processing of the multi-input series production lines using the method of max algebra ,the computational algorichm of production period for multi-input production lines and a batch of produetion on nonblocking are given.

利用极大代数方法讨论了多入口串行生产线的生产周期问题，给出在无阻塞控制下的多入口串行生产线生产周期的计算公式及其批量加工生产时的周期公式。

The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.

本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法，研究丘脑网状核(nucleus reticularis thalami，RT)中γ-氨基丁酸(gamma-amino butyric acid ，GABA)能神经元、一氧化氮(nitrogen monoxidum，NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate，cAMP)及中缝背核(nucleus raphes dorsalis，DRN)至RT的5-羟色胺(5-hydroxytryptamine，5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP，5μg)，注射当天睡眠时间略有减少，第二日睡眠时间显著减少，觉醒时间明显增多，第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后，与生理盐水组比较，睡眠时间增加，觉醒时间减少；而RT内微量注射L-谷氨酸(glutamic acid， L-Glu， 0.2μg)后，睡眠时间减少，觉醒时间增加；RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline，BIC，1.0μg)后，睡眠时间减少，觉醒时间增加；RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen，BAC，1.0μg)后，产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg，0.5μg)后，与生理盐水组对比，睡眠时间略有减少，但无显著性意义；而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside，SNP，0.2μg)后可明显增加觉醒时间，缩短睡眠时间；微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine，L-NNA，2.0μg)后，引起睡眠时间增多，觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用；RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后，与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠，其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate，MOR，1.0μg)后与生理盐水组对比，睡眠时间减少而觉醒时间增加； RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride，NAL，1.0μg)后与生理盐水组比较，睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后，与生理盐水组对比，原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较，睡眠时间增多而觉醒时间减少；RT内微量注射亚甲蓝(methylene blue，MB，1.0μg)后，与NS组比较，睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg)，同时在双侧RT内微量注射NS (1.0μg)后，与对照组(DRN和双侧RT注射NS， 0.2μg)比较，睡眠时间减少，觉醒时间增多；大鼠DRN内微量注射L-Glu(0.2μg)，同时在双侧RT内微量注射二甲基麦角新碱(methysergide， MS， 1.0μg )后，与对照组(DRN注射L-Glu 0.2μg，双侧RT注射NS 1.0μg)比较，睡眠时间增多，觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine，PCPA，10μg)，同时在双侧RT内微量注射NS (1.0μg)后，与对照组(DRN和双侧RT注射NS， 1.0μg)比较，睡眠时间增多，觉醒时间减少；大鼠DRN内微量注射PCPA(10μg)，产生睡眠增多效应后，在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan ， 5-HTP， 1.0μg )后，与对照组(DRN注射PCPA 10μg，双侧RT注射NS 1.0μg)比较，睡眠时间减少，觉醒时间增多。

We performed a simulative test, which confirms that wavelet analysis can separate annual wobble and Chandler wobble. Our results show that this method can be used in astronomical geodynamies effectively. This paper is divided into two parts. The first is about statistic characteristic of polar motion. Polar motion includes secular motion, long period fluctuations, Chandler wobble, annual wobble and high frequency wobble. The secular motion is 3.4mas/year and towards 760W meridian. Long period fluctuations have difference periods in x-axis and y-axis. They are 31.7-year and 24-year in x-axis and 28.5-year and 22.9-year in y-axis. These 2~? decades fluctuations have an amplitude of about 30 mas , and are very nearly linearly polarized, with the observed motion of pole being almost entirely along a line between 360E and 1440W. There is a 55.4-year wobble whose amplitude is 9 mas. The amplitude of the interannual fluctuations is about 4? mas. The amplitude of long period fluctuations decreased after 1970. The annual wobble is a steady wobble. It retrograde wobble is only 1/20 of prograde wobble in amplitude.

本文的工作主要分为两部分：第一部分是通过分析POLE97序列，我们对极移的统计特性有了一个较全面的认识，极移主要包括趋势项、长周期项、Chandler项、周年项和高频项：趋势项的方向是西经76°，速度为每年3.4mas；长周期项中Markowitz 项在X、Y两个方向有不同的周期，它们分别是：X方向的两个周期是31.7年和24 年，Y方向的两个周期为28.5年和22.9年它们叠加在一起是一个线偏振运动，最大振幅约为30mas，偏振方向在西经144°和东经36°之间；极移的长周期波动中还存在一个 55.4年周期的圆周运动，振幅约为9mas；十年尺度变化的振幅在4～6mas之间，在Y 方向十年尺度的成份比较多，它们的周期在X方向和Y方向不是对应的；从七十年代年开始长周期变化的振幅明显降低；周年项是一个振幅稳定的摆动，在X、Y两个方向的振幅略有差别，逆向运动振幅大约为顺向运动振幅的1/20；Chandler摆动的振幅自1900年以来经历了几次较大的变化，其中包括1915年和1955年两次极大值，振幅分别达到0&。25和0&。28，以及1925～1940期间小于0.09的过程，Chandler项在X、Y 两个方向的振幅几乎完全相等，其逆向运动振幅不到顺向运动振幅的1/50。

Three rackets sport uses short-cycle forms to build an annual multi-cycle model.

三拍&项目以微缩大周期或中小周期的形式构成全年度多周期模式。&

The foreign professional athletes of "Three rackets" sport always use the short-cycle of the annual cycle model; Chinese athletes still use the annual two-big cycle and multi-big cycle model in table tennis and badminton.

三拍项目国外职业运动员多采用中小周期的年度周期模式，乒乓球、羽毛球项目中国运动员仍然采用年度双大周期及多大周期的模式。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了