多化的

Then Doripenem came into the market in the July ,2005. We studied the synthesis of Doripemen.Firstly, we synthesized the chemical 2 from the starting material------o-hydroxylphenylacylamine through Reformastky reaction, alkylation, Diekmann reaction, enolization, esterification and etc. Secondly, we synthesized the chemical 3 from L — hydroxylproline through the protection of carboxyl, amidogen and hydroxyl group, reduction by NaBr, SN_2 substitution and Mitsumobu reaction.

我们以水杨酰胺为起始原料，经Reformatsky反应、烷基化、Diekmann环合、烯醇化、酯化等反应合成双环母核2；再从L-羟基脯氨酸出发，经酯化保护羧基、保护氨基、保护羟基、硼氢化还原酯得醇、Sn2取代和Mitsumobu反应等合成巯基侧链3；最后由化合物3经脱保护、水解得硫醇，和化合物2在二异丙基乙基胺的作用下缩合，最后Pd／C催化脱保护，历经16步反应最终得到产物多尼培南。

Recently Wang and Xiao discussed the excitation state energy of polaron in polyatomic crystals for the first time.

近年来国内外对多原子极性晶体中磁极化子性质的研究十分活跃，Zorkani等采用变分法计算了束缚磁极化子的基态能量，Kandemir等采用束缚朗道态讨论了二维大磁极化子的基态和第一激发态能量，国内一些学者采用微扰法和新颖算符法讨论了多原子极性晶体中表面和体磁极化子的性质。

The result shows that: with the expansion of teacher education space, the reform and development of Chinese teacher education is much closer or equal to that of the international teacher education. The transitional stage and education reform in China puts forward a new demand for P. E. talents. The innovation as to education object, specification and curriculum arrangement raised in P. E. Curriculum Arrangement for Chinese Universities with four-year Program published in 2003 meets such a demand, and narrows the gap of education development in high P. E. academy between China and foreign countries. P. E. teachers abroad are usually cultivated by comprehensive universities, the cultivating objectives are verified, and generalists adapted to social development are emphasized. Cultivating mode abroad are various, with "open-type" or "non-directional type" as the main mode, and 4-year program, 5-year program, and 3-year program serve as the main form of education system. Curriculum arrangement abroad stresses general education, with foundationalization, normalization, objectification, optionalization, miniaturization, internationalization and syntheticalization as its characteristics and it employs credit system. The close-typed cultivating mode of P. E. academies in China should be gradually transformed into open-type or multi-type, cultivating generalists instead of specialists, and further constructing a new one with several cultivating types co-existing. Orientation of P.E. teachers in China should follow standard principle, coordination principle, experience principle and resource principle. To improve P.E teacher education in China, the following measures can be taken: relevant laws and regulations should be made for orientation; P.E teachers" training organization should be encouraged to participate in orientation; extension and connotation of P.E. teacher education should be expanded; resources should be optimize; systematic P.E. teachers" orientations should be organized;"Life P.E. Teacher Qualification "should be changed; useful-life should be set for P. E. teacher qualification; P.E. teacher qualification should be regularly authenticated; On-job training of P. E. teachers abroad tends to be systematic, but in China P.E. teachers" on-job training and prevocational training are separated; therefore measures must be taken to change this circumstance and thus speed up the systematic process. Factors concerning constructing a new system of P. E teachers are the following: reconstructing resources, making P.E. teachers" cultivation, orientation and training systematic, establishing a mechanism for encouragement and punishment, making school-based training and college training systematic, and setting up a mechanism combining directional training with non-directional training.

研究结果表明：随着教师教育革新空间的拓展，我国体育教师教育的改革与发展水平逐步与国际体育教师教育发展趋于接轨化。2003年颁布的《全国普通高校体育教育本科专业课程方案》在培养目标和规格、课程设置上的创新性，适应了我国社会转型和教育改革对体育教育专业人才的需求，进一步缩小了与国外高等体育院系教育发展的差距；国外体育教师一般由综合性大学或文理多科性大学培养，培养目标多向化，以培养适应社会发展的通才型人才为主；培养模式灵活多样，多数以"开放型"或"非定向型"培养模式为主，学制多以4年制、5年制、3年为主；课程设置上注重通识教育，突出基础化、师范化、针对化、选修化、小型化、国际化和综合化特点，实行完全学分制的教育管理制度；我国普通高校体育教育本科专业人才培养模式应该由封闭性转向开放式混合型的人才培养模式转变，由专才型转向复合型人才培养模式转变，构建多种类型并存的人才培养模式；我国体育教师入职教育革新应遵循的原则是本位原则、协同原则、经验原则和时间与资源原则，改进措施有：做好入职教育的法规化、制度化建设，激励体育师资培育机构参与体育教师的入职教育，拓展体育教师教育的外延和内涵，优化整合资源，系统组织体育教师的入职教育，改变体育教师资格"终身制"，设定体育教师资格有效期限，推行教师资格定期认证制度等；国际上体育教师在职培训体系显现了体育教师教育一体化的发展取向，但我国体育教师的在职培训与职前培养存在分离性，必须采取改革措施，加速我国体育教师教育的一体化进程；构建体育教师教育新体系的实施要素是：重组资源配置，实现体育教师培养、入职和培训一体化，建立奖惩机制，实现校本与院校培训一体化，建立体育教师定向与非定向培养培训有机结合机制。

This paper is both a statistical and analytical investigation into the 900-odd light-tone Chinese characters and 1,100-odd "r"-suffixation characters collected in A Dictionary of Modern Chinese.

本文对《现代汉语词典》所收集的900多个轻声词和1100多个儿化词加以统计和分析，认为其中有44%左右的轻声词和45%左右的儿化词没有区别意义的作用，是否读轻声或儿化，并不影响语言表达，可以把它们从轻声词和儿化词中精减掉。

The results showed that the TiN andN films are polycrystalline phase. The properties and structure of TiN films are mainly determined by the N2 mass flow rate, and as the N2 mass flow rate increases, the structure of the TiN films transforms to f.c.c. type leading to better the properties of films. The presence of negative bias voltage can optimize the grain of TiN films, lower the defect proportion and denser the films, which improves the hardness of films. The TiN films conform to the free carrier absorption mechanism and there are many of free electrons with lower N content in TiN films. With the increase of N content, the quantity of free electrons and reflectivity of films decrease, and the plasma frequence shifts to the lower energy, which leads to the regular change of colors of films from silver, yellowy, golden to yellow-red, meanwhile the lightness of films decreases. The goldenN film consists of TiN and ZrN phase, but belongs to a sigle f.c.c. structure with (111) preferred orientation. The Zr-doping dosen't change the position of the valance band, conduction band and forbidden band ofN film, but leads to the presence of new energy levels, which is the reason thatN film remains golden. The transparent hard films with good corrosion resistance and high hardness have been prepared and the further reseachs showed that the grain size of those films is by far smaller than the wave length and the width of forbidden band of those films is very broad, is the reasons that those films are transparent.

研究表明：氮化钛和N 薄膜为多晶态，氮流量决定了氮化钛薄膜的结构和性能，增加氮流量能使氮化钛薄膜的结构向面心立方结构转变，从而得到性能良好的氮化钛薄膜；施加负偏压能优化氮化钛晶粒和减少薄膜中的缺陷，使膜层变得更致密，从而提高薄膜硬度；氮化钛主要遵循自由载流子光吸收，氮含量较少时薄膜中的自由电子数目较多，随着氮含量的增加，薄膜中的自由电子数目不断减少，反射率逐渐降低，等离子体频率向低能端移动，从而使薄膜颜色出现规律变化，由金属色银白色到淡黄、金黄再到红黄，并且薄膜亮度呈下降趋势；金黄色的N 薄膜中存在TiN 和ZrN 的分离相，但其为单一的面心立方结构并具有(111)面择优取向；相对于TiN 薄膜，Zr 掺杂后，并没有使薄膜的导带、价带和禁带发生变化，只是在TiN 禁带内增加了新能级，这也正是掺杂Zr 后，薄膜仍

Taking Changling County, Zhenlai County and Da'an City of Jilin Province as researchareas, based on remote sensing data, graphics operation and spatial analysis are carried out indifferent points of views, including temporal, spatial, scale and landscapeetc; all aspects analysis of this dissertation are abstractively expressed by digital graphics andseries of curves which are not stick to one pattern to discussing multi-dimension andcomplicated attributes of the salinized process. Linking up temporal-spatial characteristicswith landscape indices while combining mathematics model and Geo-informatic TUPUmodel, this dissertation puts forward the fundamental frame: temporal-spatial evolvementpattern, spatial extension process analysis and landscape characteristics analysis of salinizedland. Temporal-spatial evolvement pattern analysis extracts the essential quantity features andtransformation modes of salinized land, and also analyzes patches spatial geometricalparameters scale feature; spatial extending process analysis discusses the change rate andecological modes; landscape feature analysis utilizes landscape graphics indices to describesalinized land microcosmic graphics features and changes.

信息图谱模型为土地盐碱化研究提供了一种谱系化、定量化与定位化相结合的研究方法，本文选取吉林省西部盐碱化典型区域长岭县、镇赉县、大安市作为研究区，以遥感影像为基础数据，在GIS技术支持下，从时空变化、尺度效应、景观特征等多个角度对盐碱化土地进行图形运算、空间分析，通过不拘一格的数字化图形、曲线系列抽象表达出不同维度上的特征与规律，探讨土地盐碱化过程的多维性与复杂性，将盐碱化土地时空特征与景观特征衔接、数学模型与图谱模型结合，以盐碱化土地时空演变基本模式、空间扩展过程和景观特征分析为框架构建盐碱化土地信息图谱模型研究体系，发挥图谱模型数据挖掘、知识发现的特长，将宏观动态变化与微观特征相联系，进一步挖掘土地盐碱化过程与人类活动影响的关系，为探索研究区盐碱化土地成因、过程，预测其未来发展变化趋势及其对环境影响提供相关科学依据。

The invention discloses a LCD panel, colorful filter piece and making method, which comprises the following steps: providing a base; forming a buffer material layer on the base; forming patterned lightproof layer on the buffer material layer; adopting patterned lightproof layer as lid to pattern the buffer material layer to form a patterned buffer layer; forming a separating piece through patterned lightproof layer and patterned buffer layer; making the separating piece form multiple pixel areas on the base; forming a colorful filter layer in each pixel area.

本发明公开了一种液晶显示面板、彩色滤光片及其制作方法，其中彩色滤光片的制作方法包括下列步骤：首先，提供一基板，并在基板上形成一缓冲材料层。接着在缓冲材料层上形成一图案化遮光层。以图案化遮光层为罩幕来图案化缓冲材料层而形成一图案化缓冲层，使得该图案化遮光层与图案化缓冲层共同形成一隔离件，且隔离件在基板上形成多个像素区域。然后在每一像素区域内分别形成一彩色滤光层。

The experimental results show that the distributions of content and toxicity equivalent quantity of PAHs in raw coal are similar to coal gasification but this compositions and contents are different. The rise of coal rank leads to the decrease of the content and TEQ of PAHs in raw coal and the increase of TEQ during coal gasification, while the content of PAHs emission from coal gasification increases first and then decreases with the increase of coal rank. The total PAHs contents generated in coal gasification of some sorts of coals are higher than in raw coal. The types of PAHs formed in coal gasification include undecomposed PAHs in raw coal, pyrosysthensis PAHs, and radical polymerization PAHs at high temperature.

试验结果表明：煤气化前后多环芳烃质量分数和毒性当量质量分数的分布特徵相似，但多环芳烃的组成和质量分数不同；煤化程度增加，原煤多环芳烃质量分数和毒性当量质量分数减小，煤气化多环芳烃质量分数先增后减，毒性当量质量分数与煤化程度呈线性关系；部分煤种气化多环芳烃的质量分数高於原煤多环芳烃质量分数，且煤气化多环芳烃的种类分为原煤未分解的多环芳烃、热解合成的多环芳烃、自由基高温缩合生成的多环芳烃。

In order to integrate the multi-earth stations,achieve the source shared and centralized management,and increase the synthetical benefits of the multi-earth stations and the system reliability,a matrix source-shared system for multi-earth station is designed,and the design method and the application condition are expatriated in the article.

为了把多个地球站有机地集成到一起，实现资源共享和集中管理，进一步发挥多个地球站的综合效益，提高系统可靠性，文中设计了多地球站矩阵化资源共享系统，阐述了系统的设计思想和应用条件，并在工程中实现了多地球站矩阵化资源共享系统的改造项目。

Liao source building glass products cover a number of types of building glass, the existing production lines, including two of the level of steel line, two lines of bending steel, a Low-E glass fiber reinforced plastic of line, two folders plastic glass production line, a hollow glass production line A GLAZE glass production lines, two bending glass production line, two one-step color folder folder wire glass production lines, three bilateral milling machine, automatic glass cutting machine Paul Quintero, many Units milling machine, positioning drilling machine, different line milling machine, Beveling machine, such as production equipment.

燎源建筑玻璃产品涵盖了多个种类的建筑用玻璃，现有生产线包括两条水平钢化线、两条弯钢化线、一条Low-E玻璃钢化线、两条夹胶玻璃生产线、一条中空玻璃生产线、一条彩釉玻生产线、两条热弯玻璃生产线、两台一步法彩夹夹丝玻璃生产线、三台双边磨边机、全自动保特罗玻璃切割机，多台磨边机、定位钻孔机、异行磨边机、斜边机等生产设备。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新