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Since the etiologic diagnoses of hepatitis A, B, C, D and E were established, there are still a part of patients with hepatitis in which the pathogenic causes can not be identified. After a lot of epidemiological and laboratory investigations, it was speculated that other parenterally transmissible pathogens causing human hepatitis existed.

自从建立起甲、乙、丙、丁、戊5种肝炎病毒的病原学诊断之后,仍有少部分肝炎患者的病因得不到明确,因此不少学者试图探索是否还有新型肝炎病毒的存在,并进行了大量的流行病学和实验诊断的研究,认为的确存在可经肠道外传播并引起人类肝炎的致病因子。1995年Simons等成功地克隆出2株黄病毒RNA序列,称之为GBV-A、GBV-B。

To investigate the expression of alpha-fetoproteins in peripheral blood of patients with hepatocellular carcinoma.

目的 探讨甲胎蛋白-mRNA在原发性肝癌患者外周血中的表达和临床意义。

No interference was found with conventional drugs, except vancomycin and methylprednisolone. The average concentrations of phenacetin and paracetarnol were (5.94 ± 4.79) and (8.81 ± 2.91)μg/mL in serum,(3.25 ± 1.10) and (570.45 ± 187.13)μg/mL in urine in the 13 healthy volunteers.

除万古霉素和甲泼尼龙外,其他临床常用药物对测定无干扰。13名健康受试者血清中非那西丁和总对乙酰氨基酚浓度为(5.94±4.79)和(8.81±2.91)μg/mL;尿液中非那西丁和总对乙酰氨基酚浓度为(3.25±1.10)和(570.45±187.13)μg/mL。

Results. Clinical resolution of infections, normalization of lab values, and bony fusion, based on dynamic radiographs and CT scans, were seen in all patients at latest follow-up. Staphylococcus aureus was the most frequently identified organism (8 patients). Four (29%) patients had positive blood cultures. Predisposing comorbidities were present in 12 patients. Six patients had epidural abscesses. Eight (57%) patients presented with neurologic deficits, ranging from paraparesis to quadriplegia. Complete recovery was seen in 7.

结果:临床上炎症消失、实验室检查数据正常和骨融合由所用患者随访的动态平片和CT扫描结果决定。8名患者频发金葡球菌感染,4名(占29%)患者血培养出现耐甲氨西林金葡球菌阳性反应,12名患者出现并发症,6名患者出现硬膜外脓肿,8名患者出现从下肢轻瘫到四肢瘫痪的神经损伤,7名患者完全康复。

To an asymmetric synthesis of (1), we applied a type of Roush addition in the first step to introduce the C4 stereocenter, and then the chair substance -122 are readily transformed into the title compound -aphanorphine using the same route as to the racemic target molecular.

aphanorphine分子的不对称合成是在第一步通过对甲氧基苯乙醛(119)发生Roush反应引入手性,得到手性高烯丙醇-122,然后利用与合成外消旋目标分子相同的方法,光学纯化合物-122经一系列转化可得到光学纯中间体化合物139;化合物139发生分子内傅—克反应的过程中,由C4位手性立体特异地控制C1位手性的生成,从而解决-aphanorphine分子中的手性问题。

By using high performance liquid chromatographycombined withthin-layer chromatography,three PG:salicin,salicortin and deltoidin weredetected in the bark of P.deltioides,Five kinds of PG were detected in the leaves,which included trmuloidin and tremulacin besides the three PG.

采用薄层色谱与高效液相色谱法相结合的方法,在实验材料的树皮中测定到三种主要的酚甙类物质:水杨甙、柳皮甙和美洲黑杨甙,在叶片中测定到5种酚甙类物质,除上述3种物质外,还包括2′-苯甲酰水杨甙和颤杨甙,对于后两者在前人的研究中未见报道。研究还对5种化学物质进行了分离。

Methods:265 patients with chronic anal fissure were subjected to the following therapy:lateral lysis of internal sphincter with small needle-knife combined with local injection,with methylene blue local injection,sitz bath with chinese meteria medica,and externally-used conpound glycerin nitrate ointment.

目的:为了提高肛裂的治疗效果。方法:采用小针刀行侧方内括约肌松解术加局部注射,复方亚甲蓝局部封闭,配合中药坐浴,复方硝酸甘油膏外涂,综合治疗陈旧性肛裂265例。

The results obtained by electron microscopic observation show that the supercoiled pUC18 DNA adopts a doughnut-like solenoidal structure with outside diameter about 43.8 nm and inside diameter about 2.0 nm in ammonium acetate-H2O medium.

观察结果显示:在疏水性的甲酰胺-水展开系统中,DNA采取通常的互缠式结构;在含有1.5 mmol/L醋酸铵的水介质中制备的超螺旋DNA标本,DNA采取线圈型结构,测得pUC18 DNA分子这种结构的外直径约为43.8 nm,内直径约为2 nm。

Results A novel polymorphism in the ABCA gene was found in two patients:M V which exists in exon7 of ABCA gene and it's cDNA location is A09G and converses amino acid from Me thionine to Valeric.

果M V是一个新发现的ABCA基因SNP,此位点在外显子7,cDNA位置为A09G,并导致位氨基酸由甲硫氨酸转变为缬氨酸。

When anthrone react with aryl aldehyde in the presence of pyridine by using xylene as the solvent,besides 10 arylmethylene anthrone derivatives we found other oxygenated anthrone which have not been reported.

发现其生成物中除含有目标化合物 1 0 -芳香基甲叉基蒽酮外,还含有部分文献中没有报道的蒽酮氧化物,经物理方法确定其为蒽醌。

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