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The compounds are represented by the structural Formula 1, Chemical formula should be inderted here as it appears on the abstract in paper form. a prodrug thereof, or any pharmaceutically acceptable salt, solvate, isomer or racemic mixture of the compound or said prodrug wherein R1 is heteroaryl, N-arylaminocarbonyl, N-heteroarylaminocarbonyl, benzimidazolyl or benzothiazolyl; R15 is present or not and if present is H, aryl, alkyl, arylalky or heteroarylalkyl; A is aryl, heteroaryl, cycloalkyl, cycloalkylidene, heterocycloalkylidene or heterocycloalkyl wherein said aryl, heteroaryl, cycloalkyl, cycloalkylidene, heterocycloalkylidene and heterocycloalkyl moieties may be substituted or unsubstituted; and B, L, X and R18 are defined herein.

所述化合物用结构式1表示,包括其前药或所述化合物或所述前药的任何药学上可接受的盐、溶剂合物、异构体或外消旋混合物,其中R 1 为杂芳基、N-芳基氨基羰基、N-杂芳基氨基羰基、苯并咪唑基或苯并噻唑基;R 15 存在或不存在,如果存在,则为H、芳基、烷基、芳基烷基或杂芳基烷基;A为芳基、杂芳基、环烷基、环烷叉基、杂环烷叉基或杂环烷基,其中所述芳基、杂芳基、环烷基、环烷叉基、杂环烷叉基和杂环烷基部分可被取代或未被取代;B、L、X和R 18 如说明书所定义。

We analyzed the polymorphism of MHC class II B gene in 14 Chinese alligators sampled from three different areas: the wild population of Xuancheng in Anhui, the captive population of Changxing in Zhejiang and the captive population of Anhui Research Center for Chinese Alligator Reproduction. The gene fragment was amplified using a pair of specific primers designed from the MHC gene sequence of the Spectacled caiman. A total of thirty-four different sequence (15, 10 and 9, respectively) were detected in sampled Chinese alligators.

为了研究扬子鳄种群MHC基因的多态性,我们选取了安徽宣城野生扬子鳄种群、安徽省扬子鳄繁殖研究中心饲养种群和浙江长兴饲养种群三个亚种群的14条扬子鳄,利用一对特异性引物扩增出扬子鳄MHC II类B基因第三外显子的部分片段,并对其进行了克隆、测序,结果从这些扬子鳄样本中共获得34种不同序列,每个亚种群内分别检测到15,9和10个不同序列。

After mud-sediment changed into stone,the water flowing in pores of middle layer of mudstone has to overcome the starting resistance resulted from the water film forming in pores.Water is easily preserved in the pores and forms the undercompaction of the mudstone layer.

当泥质沉积物成岩以后,地层中部的孔隙水必须克服微孔隙对其产生的启动阻力才能向外排出;否则,地层水就被滞流在岩层孔隙中并造成泥岩的欠压实。

Which I produced the 201-silicone oil due to a special production process, with the exception of a 201-all the characteristics of silicone oil, silicone oil in the non-heavy metal, non-catalyst residues and decomposition products, thus non-toxic , Tasteless, odorless features more prominent, and it has a good low-temperature-resistant high-performance, high flash point, low freezing point, steam down, a good anti-oxidation and chemical stability in industrial and agricultural production, defense industry, scientific research And medical and public health departments, are an excellent application.

其中我公司生产的201甲基硅油由于采用了特殊的生产工艺,除具备201甲基硅油的一切特性外,在硅油中不含重金属,不含催化剂残留物和分解物,因而无毒、无味、无嗅的特点更为突出,它具有良好的耐高低温性能,闪点高,凝固点低,蒸汽压低,良好的抗氧化性和化学稳定性,在工农业生产、国防工业、科学研究及医疗卫生等部门,都得到了极好的应用。

Methods The peripheral blood lymphocytes were stimulated by Stimulator in order to enhance expression of cytokines .

先用刺激物刺激外周血T细胞,以增加细胞内细胞因子的表达,继用流式细胞仪分析特异性细胞因子表达水平。

The smaller ones are ca 70 nm wide and join the tectum and the larger columellae. These larger ones appear to be composed of several 70 nm in width rods. They join the distal surface of the foot layer. The proximal surface of the foot layer is marked by a white line (referred to as a junction plane) where it joins the endexine.

柱层中有种大小同的柱体,较小的宽约70 nm接盖顶层和较大的柱体,而较大的柱体是由多个宽70 nm的棒物所组成的,它们会和基层末端相,而基层顶端表面有著明显分布的白线特徵,就好像是它与外壁内层的接合面。

Objective To find the effect of secretion from vulval cancer on the result of urine routine test.

目的:了解外阴癌分泌物对尿常规检查结果的影响。

The data showed that more styrene was absorbed than tetrachloroethylene at low-exposure.

同时用代谢动力学参数外推出在不同的暴露浓度下其代谢物的消除量。

The pI of these components gradually decreased f rom pH 4.0 according to electrophoresis mobility from higher to lower on PAGE. The molecular weights were in the range of 22~34 ku. 6.5 and 7 w ere glycoproteins proved by staining with the shiff reagent and thymol/sulfuric acid. The fibrinolytic activity of 7 was highest as determined usi ng chromzym UK and chromzym PL as specific substrates.

这些组分的等电点按照它们在聚丙烯酰胺凝胶电泳图谱上的顺序从4.0开始依次降低;SDS-PAGE证明,除3、4外,其余组分均只含一种多肽链,分子质量在22~34ku之间;用shiff试剂和酚-硫酸染色,显示1、2、6.5和7是糖蛋白,其中7的糖含量最高;以BAEE、Chromozym UK和Chromozym PL为底物测定,7的纤溶酶活性最高。

TW-600 Outside pumping vacuum packer: using air pressure style sealing, and it is clean and reliable; adopting the Japanese and Korea technology and equipment, is provided with dual functions of vacuum and charge; the whole machine circuit is from Korea and is programmable control, and is stable; sponge shape silica gel bar to ensure a fine airproof after pumping out the air; using the variable stroke air cylinder to make sure the sealing is neat and tidy; it is a perfect safe packaging after the product charge; stainless platform, and can adjust the height freely in terms of the size of the packaging goods; and also can change the work place easily for its installing truckle; simple style storage case to store the vacuum packaging bag or spare part in common use; Light touch style padding switch can be operated conveniently.

TW-600外抽式真空包装机:采用气压式封口,干净、可靠;日、韩先进的技术设备,具有真空及充气双重功能;整机电路由韩国可编程控制,性能稳定;海棉状硅胶条,确保抽气后密封良好;采用变行程气缸,使封口整洁平整;充气后产品理想的安全包装;不锈缸工作台,根据包装物的大小,任意调整高低;装有脚轮,可任意移动工作地点;简易型储物盒,存放真空包装袋或常用备件;轻触式脚踏开关,方便操作。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。