外曲

Results: The title compounds exhibited potent antifungal activities against nearly all fungi tested (except for Aspergillus fumigatus), especially for the deep infection ones. Compounds 6a, 6d, and 6j showed a 16-fold activity (with a MIC80 value of 0.015 6 μg/ml) as that of fluconazole against Microsporum gypseum.

结果：体外抑菌测试结果表明，所有化合物对除熏烟曲霉菌外的所有菌株均有一定程度的抑制活性，对深部真菌的抑制活性明显优于浅部真菌。

MTT assay FAK signaling pathway inhibitor genistein on human corneal epithelial cell cytotoxicity;RT-PCR detection of human corneal epithelial cells adhesion to fungus at different times,extracellular matrix protein including laminin,fibronectin,FN glass,Ⅳcollagen,transmembrane protein integrinαⅤ,integrinβ1(ITGβ1),as well as the FAK signaling pathway FAK1,FAK2 and Paxillin gene expression;Western blot detection of the signal transduction pathway adhesion-associated protein ITGβ1,FAK and PAX expression and the inhibition of genistein. Immunocytochemical method was used to observe the LN,FN and FAK expression in human corneal epithelial cells during interaction with the fungues;Laser scanning confocal microscope had a cell positioning on FN,FAK and PAX,observed the changing of the human corneal epithelial cytoskeleton after stimulated by fungues;Quantitatived by flow cytometry to detect of human corneal epithelial cells with PAX at ITGβ1 fungal expression after adhesion;Optical microscopy quantitied the fungues and human corneal epithelial cell adhesion and recorded to determination the integral optical density afrer adhesion;Scanning and transmitted electron microscope observed the changing of cell ultrastructure after fungues and human corneal epithelial cell adhesion.

第一部分真菌激活人角膜上皮细胞FAK信号转导通路的体外实验研究将三种常见致病真菌(白色念珠菌、烟曲霉菌和茄病镰刀菌)分别与人角膜上皮细胞共孵育，MTT法检测FAK信号通路抑制剂染料木黄酮的对人角膜上皮细胞的细胞毒性作用；RT-PCR检测真菌黏附人角膜上皮细胞后不同时间细胞外基质层连蛋白、纤连蛋白、玻连蛋白、Ⅳ型胶原、跨膜蛋白整合素αV、整合素β1(ITGβ1)，以及FAK信号通路中FAK1、FAK2和桩蛋白基因的表达情况；Western blot的方法检测黏附信号转导途径相关蛋白ITGβ1、FAK和PAX的表达，以及染料木黄酮对真菌刺激人角膜上皮细胞FAK信息通路活化的抑制作用；免疫细胞化学方法观察人角膜上皮细胞与真菌相互作用过程中LN、FN和FAK的表达；激光共聚焦显微镜对FN、FAK和PAX进行了细胞定位，并观察真菌刺激后人角膜上皮细胞骨架的变化；流式细胞仪定量检测人角膜上皮细胞ITGβ1与PAX在真菌黏附后表达的改变；光学显微镜观察真菌与人角膜上皮细胞黏附数量，记录并测定了黏附后积分光密度值OD扫描及投射电镜观察了真菌与人角膜上皮细胞黏附后，细胞超微结构的改变。

a three steps sequence therapy was designed for patients suffered post dural puncture headache total 45 cases:step one,patient keep supine recumbence,and intravenous injection of ringer's solution 1000ml with intramuscular injection of tramadol 100mg was administrated. if pdph could not relieve within 24hr,the next step should be use. step two,drinking a cup of coffee three times a day for patients who were allowed to eating or intravenous injection ketamine 0.5mg/kg for patient in fasting diet.

选择椎管内麻醉后发生头痛的病例共45例，按设定的序贯疗法分别为a：去枕平卧1d，每天补液量增加1000ml平衡液，肌注曲马多100mg，无效时进入b和c；b：能进食者给予市售咖啡饮品，每天三次；c：不能进食者静脉注射氯胺酮0.5mg/kg，连用2d；以上治疗无效时进入d：行硬膜外填充自体血10ml。

A three steps sequence therapy was designed for patients suffered post dural puncture headache total 45 cases:step one,patient keep supine recumbence,and intravenous injection of Ringer's solution 1000ml with intramuscular injection of Tramadol 100mg was administrated.

选择椎管内麻醉后发生头痛的病例共45例，按设定的序贯疗法分别为A：去枕平卧1d，每天补液量增加1000ml平衡液，肌注曲马多100mg，无效时进入B和C；B：能进食者给予市售咖啡饮品，每天三次；C：不能进食者静脉注射氯胺酮0.5mg/kg，连用2d；以上治疗无效时进入D：行硬膜外填充自体血10ml。

2 As long as internodes, conspicuously longitudinally ribbed only toward their apex, cartilaginous, gray or yellow-gray setose, margins densely yellow-brown setulose; auricles falcate, unequal; oral setae yellow-brown, 2–7 mm; ligule arcuate, short; blade erect, linear-lanceolate, glabrous.

分枝5-15，外折。逐渐的竿箨脱落，叶耳镰刀形，不等长；口头的刚毛黄褐色，2-7毫米；叶舌弧曲，短；叶片直立，线状披针形，无毛。

Study on ultrasonic-assisted extraction and physicochemical properties of red pigment in Zingiber mioga Rosc;2. Studies on the best extraction of red pigment from Paniculed Gold-rain tree fruit peel

变色玻璃曲otoehromi.glass在萦外尤联，光二中的蓝紫光辐照下，能够在可见光区域产生光吸收而着色，去除辐照后又可逆地回复其原始状态的一种玻璃jm业洛沽该

The winkling model in the process of drawing was developed on the base of Hills bifurcation-point bulking theory, which became the theoretical basis of the analysis of flange wrinkle and side-wall wrinkle.

本文在Hill分叉点失稳的能量法则的基础上建立了半球形零件拉深成形的皱曲模型，该模型是分析内皱及外皱的理论依据。

Besides the 30,000 frequently used phrases, there are 12 professional word-stocks are appended. The new function to construct phrases from taking the Characters from the screen and delete the phrases from the word-stock is convenient and agile. Also the Wangma Intellectual Pinyin Input Method is designed to the software. The unique Help and encoding prompt functions are added to the new software. The originated 'Retractile Antenna' Character sets switch method reduces identical codes greatly so as to improve the inputting speed greatly. The software adopts new simplified and traditional Character Roots list and originally creates the Three Grades to learn the Cross-codes that enables the beginners to learn the Method easily.

除系统自带的3万条常用词汇外，还特别设计了12种专业词库共10万条专业词汇，用户可以灵活选用；设计了屏幕取字造词功能，随造随用，灵活增删；增加了独特的&帮助&及编码提示功能；首创了&拉杆天线&式字集切换法，进一步减少了重码，使输入效率大为提高；推出了简繁兼备、配曲可唱的新字根表；安装了辅助的&王码智能拼音输入法&；独创了&识别码三段学习法&，为初学者由初级向高级过渡架设了阶梯。

They talked about fiddle tunes and the fiddlers that Pappy and the old man had known here in the mountains.

吃完饭，三个人坐在小木屋外春日的阳光下，他们聊着小提琴曲以及这山里帕皮和老人所知道的小提琴手们。

After they had eaten, the three men sat in the spring sunshine outside the cabin. They talked about fiddle tunes and the fiddlers that Pappy and the old man had known here in the mountains.

吃完饭，三个人坐在小木屋外春日的阳光下，他们聊着小提琴曲以及这山里帕皮和老人所知道的小提琴手们。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。