外显子

PCR-RFLP in FSHR gene 5'–flanking region with exon 1 digested by restriction endonuclease TaqⅠdemonstrated that the frequencies of allele A (0.5500) and genotype AA (0.5000) in twinning cows were higher than that of allele A (0.3500) and genotype AA (0.3000) in monovular cows for Qinchuan cattle, while The frequencies of allele B (0.5937) and genotype BB(0.6875) in twinning cows were higher than that of allele B (0.5416) and genotype BB (0.4167) in monovular cows for Holstein cattle. Key words: Bovine; Twinning; FSHR gene; PCR-RFLP

FSHR基因5'端（包括侧翼序列和第一外显子）的限制性内切酶TaqⅠ的PCR-RFLP标记研究发现，在秦川牛中双胎母牛的A基因频率（0.5500）和AA基因型频率（0.5000）分别高于单胎母牛的A基因频率（0.3500）和AA基因型频率（0.3000）；在黑白花奶牛中双胎母牛的B基因频率（0.5937）和BB基因型频率（0.6875）均高于单胎母牛的B基因频率（0.5416）和BB基因型频率（0.4167），也就是FSHR基因的5'端的PCR-RFLP标记在一个品种内单胎母牛和双胎母牛之间有一定趋势，但两个品种的趋势不同。

Methods: Mutational analysis for EGFR exons18, 19, 20 and 21 was performed in 64 patients.

分析和检测64例肺腺癌石蜡包埋标本EGFR基因突变状况，采用PCR 和序列分析技术进行EGFR 基因18、 19 和21外显子突变分析。

Results We had 22 deletion mutational cases and 6 point mutations from 35 clinical specimens.

在22例缺失突变病例中，有10例为不完全缺失突变即有低于外显子509 bp的扩增产物。

ResultsDifferences of the PTEN expression were significant between NPC and nasopharyngitis (P＜0.05). Expressions of PTEN were closely related to lymph node metastasis and clinical TNM stage(P＜0.05). None of 52 cases showed mutation in exon5 and 8 of the PTEN gene in NPC.

结果鼻咽癌中PTEN蛋白表达率低于癌旁组织，表达与临床TNM分期、颈部淋巴结转移密切相关（P＜0.05）。52例鼻咽癌中PTEN基因第5、8外显子未见明显突变。

Six pairs of oligonucleotide primers were designed to amplify and sequence scarlet gene of mutant stbr flies which were obtained by outcross between Bar and wild type flies.

设计了6对引物对本实验室由棒眼果蝇Bar与野生型果蝇杂交所产生的亮红眼突变型果蝇stbr的scarlet基因进行了测序，结果在scarlet基因的第4外显子检测到了一个7.5kb的插入，进一步的测序证实此7.5kb插入为逆转座子412元件。

Objective: To detect the deletion and point mutation of WW domain containing oxidoreductase exons 6-8 in human primary cultured lung carcinoma cells and the relationship with clinical pathological indices thereof.

目的：探讨肺癌原代培养细胞中的抑癌基因WWOX第6~8外显子的缺失及点突变情况及其与临床病理指标的关系。

Analysis for microsatellite instability was performed on 5 paired samples of lymphocyte DNA and paraffin embedded or fresh-frozen tumor tissue.

结果：在该家系的2例结肠癌患者中均发现hMSH2基因第13外显子2108位出现C—A的错义突变，导致703位Ser变异为Tyr，即C.2108C〉A

The outcome of the operations is good effect on the PD patients with parkin gene deletion mutations.

尤其是有关Parkan基因外显子缺失的PD患者手术效果的报道，尚未见到。

Objective To explore parkin gene deletion mutations at exons 3 to 7 in Chinese familial patients with Parkinson's disease as well as the association with the clinical features.

目的 探讨中国家族性帕金森病患者parkin基因第 3～ 7外显子是否存在缺失突变，及其与该病临床特点的关系。

We found that it was G mutated to A at 948 point in Myostatin gene cDNA sequence in deer.

结果表明，位于Myostatin基因DNA序列第3外显子948处发生G→A突变。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。