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The inhibin a gene、 the bone morphogenetic protein 4 (BMP4) gene and the bone morphogenetic protein 7 (BMP7) gene were studied as candidate genes on the prolificacy of Small Tail Han sheep. Single nucleotide polymorphisms of 5 ' regulatory region、 exon 1 of INHA gene;exon 2、 exon 3 and exon 4 of BMP4 gene and exon 2、 exon 3 of BMP7 were detected in high fecundity breed and low fecundity breeds (Chinese Merino sheep, Corriedale sheep and South African Mutton Merino sheep) by PCR-SSCP. The results indicated that there was a mutation (316C→T) in 5' region of INHA gene in Small Tail Han sheep, Chinese Merino sheep and Corriedale sheep, the same mutation did not exist in South African Mutton Merino sheep.

采用PCR-SSCP技术检测抑制素α(inhibin α,INHA)基因5'调控区、外显子1,骨形态发生蛋白4(bone morphogenetic protein 4,BMP4)基因外显子2、外显子3和外显子4以及骨形态发生蛋白7(bone morphogenetic protein 7,BMP7)基因外显子2和外显子3在高繁殖力绵羊品种以及低繁殖力绵羊品种(中国美利奴绵羊、考力代绵羊、南非肉用美利奴绵羊)中的单核苷酸多态性,同时研究这三个基因对小尾寒羊高繁殖力的影响。

Creative industry zones in centre of Shanghai are more than exurban, but the scale is smaller. There are a lot of creative industry zones around universities and scientific research institutions.

上海创意产业集聚区的区位特征表现在,集聚区集中分布在市中心区域,内紧外松、内小外大行业集聚的空间分异明显,高校创意产业集聚群已显现。

An originative, technological approach that a doped poly-silicon layer is grown on extrinsic base before MBE SiGe base epitaxy is proposed, which minimizes the contact resistance of base and eliminates the native oxide at both internal and extrinsic base pads.

对SiGe HBT器件的性能进行了仔细研究,提出了在进行SiGe基区外延之前淀积掺杂多晶硅的新器件结构,该结构消除了外基区掺杂Poly—Si和基区SiGe接触之间的自然氧化层对基区接触电阻的影响,减少了基区接触电阻。

The comparative investigation of the characteristics of deformation and AE were conducted and the results are presented as followed: 1. The characteristics of rock AE are correlated to the strength, joints, cracks, and the size and hardness of crystalline grain. 2. The sequence of AE can be divided into four phases: beginning phase, tempestuousness phase, drop phase and dreariness phase. The loss and the duration of the phases are correlated to the rock character and flaws in the rock. 3. The AE rate characteristics are not almost concordant with the AE energy rate. 4. Besides the homogeneity, the strength of rock contributes the activity of AE. The higher the strength is, the lower the activity is. 5. There is a dreariness phase before the failure of most kinds of rock. 6. Whether the precursor is obvious is correlated to rock the character, and the precursor of AE rate is more apparent than the precursor of AE energy rate comparatively.

通过对比研究这六种不同岩石的变形和声发射特征发现,岩石声发射受到岩石强度、节理裂隙和晶粒软硬大小等的影响;岩石声发射过程存在初始区、剧烈区、下降区和沉寂区,各个阶段是否存在及持续时间与岩石强度、内部缺陷等有关;岩石的声发射事件率特征与能量率特征并不完全一致;岩石的声发射活性除了受其均匀性影响外,还受到岩石的强度影响,强度越小,声发射活性越强;大多数岩石破坏前存在一声发射沉寂区;岩石的破坏前兆是否明显跟岩性有关,相比较而言,岩石破坏时的声发射率前兆比声发射能量率前兆更为明显一些。

The charts of velocity vector of flow field outside the tube under five conditions with amplitude 1.3 mm and frequency 5—25 Hz were obtained,and the cosine of average synergy angle of flow field outside the tube was calculated.

实验及模拟结果表明:振动能够显著增加管外近壁区的流体速度,能够在振动方向上的管壁两侧形成有效的冲刷,随着振动频率的升高其管外近壁区的平均速度近似呈线性增加,在共振点出现峰值;相同区域内振动工况的平均场协同角余弦值要明显大于无振动工况,但不同振动频率间的场协同角余弦值变化较小。

Sample collection: Two hundred and fifteen sera samples of normal population were collected from the peripheral blood of healthy blood donors of Shenyang, and the sera were separated by centrifugation after blood clotting; The patients sera were collected from the outpatients and inpatients of No. 1 hospital of China Medical University and the Second hospital of Jilin University. Syphilis was confirmed by clinical and serum test of TPHA and RPR; That of pemphigus vulgarism was confirmed not only by clinical, histopathological examination, but also by direct and indirect immunofluorescence test. DIF test on lesion or non-lesion skin showed immunoglobin and/or C3 deposits in the intercellular space of epidermis, and IIF test showed positive anti- intercellular antibody in patient serum using mouse's or rat's tongue or esophagus as substrate.

标本的收集:正常人的血清:采集沈阳市正常献血员外周静脉血共215份,待血凝后离心分离血清;患者的血清:来自中国医科大学一院及吉林大学二院门诊及住院部的病人,梅毒患者除了病史及临床表现外,全部经血清学TPHA及RPR确认;寻常性天疱疮患者除了临床及组织病理诊断外,还进行了直间接免疫荧光的检测,直接免诊断疫荧光:在皮损区及非皮损区的表皮细胞间显示IgG和/或C3补体沉积;间接免疫荧光用鼠或兔的舌或食管作为底物,在病人的血清中显示有肯定的细胞间抗体。

And they systematically studied the effect of the activate spleen-energy law on digestive and absorptive function, it is confirmed that the activate spleen-energy law have significant regulation effect on the action and secretion of gastrointestinal tract. Recently, we established the juvenile rat model with anorexia by imitating the major cause of children and found that the CCK-8S concentration in hypothalamus and periphery blood of the anorexy model was obviously increased .We also found the appestat that the spontaneous discharge frequency of LHA neurons was decreased and the spontaneous discharge frequency of VMH neurons was increased.

近几年,我们采用病因模拟法成功建立了幼龄大鼠厌食模型并发现该模型下丘脑和外周CCK-8S水平显著增高,食欲中枢——下丘脑外侧区神经元自发放电频率减低和下丘脑腹内侧区神经元自发放电频率增加,临床治疗小儿厌食有可靠疗效的运脾复方不仅可调节外周血中与摄食有关的肽类激素水平,如降低CCK-8S水平,而且能调节下丘脑食欲中枢神经元的自发放电频率。

CML is cytogenetically marked by the philadelphia chromosome, which originates from a reciprocal translocation between chromosome 9 and 22 and is molecularly marked a chimeric bcr-abl gene, resulting from juxta-positive of the abl proto-oncogene on chromosome 9 with the bcr gene, which is normally located on chromosome 22. The chimeric bcr-abl gene expression an 8. 5kb hybrid mRNA transcript giving rise to a 210-KD fusion protein (P210〓) with increased tyrosine kinase activity. P210〓 plays a key role in the pathogenesis of CML. The continuous cell line K562 was established from the pleural effusion of a 53-year-old female with CML in terminal blast crisis, and was a human erythroleukemia line, contained Ph chromosome.

绝大多数慢粒患者白血病细胞中具有Ph染色体,是由9号染色体长臂3区4带和22号染色体长臂1区1带相互易位形成,即t(9;22),使位于9q〓的c-abl原癌基因在第二外显子的5'端断裂并易位到22 q〓的M-bcr基因第2或第3外显子的3'端,形成异常的bcr-abl嵌合基因,该基因转导出异常的mRNA,编码并翻译出P210蛋白,该蛋白具有很强的酪氨酸激酶活性,使粒细胞发生恶性增殖。K562细胞属于慢粒急变、红白血病细胞株,具有Ph染色体。

Results of orientation mensuration of two successive years showed that:①The mulching enhanced the difference in the number bacteria and fungi in rhizospere and bulk soil, and increased the R/B of number of edaphon in rhizospere and bulk soil.

①覆盖处理能强化玉米根区、根外细菌及真菌的数量差异,提高玉米根区与根外土壤微生物数量比值。

We organized and identified the specimens which collected in the insects specimens laboratory of life science and technology department of Xinjiang university, from almost everywhere of Xinjiang with combination of the conventional methods and the electroscopic scanning technique.

本文采用常规鉴定方法与雄性外生殖器解剖相结合,辅以扫描电镜观察,对收藏于新疆大学生命科学与技术学院昆虫室20年来积累的标本及三年在校期间系统地采集于全疆各地的拟步甲类标本进行了整理与鉴定,结合野外考察及重要类群的生物学研究,研究其区系成份,并对其区系特征及地理分布状况进行了系统的分析,主要研究成果如下:1)初步查明新疆拟步甲科昆虫共计266种,分隶于23族72属,其中35种为中国新记录种,3种为拟步甲类新种,作新种记述,并附图片;在研究过程中初步探讨了拟步甲的中文命名问题; 2)新疆拟步甲种类繁多,其区系成分分析显示,除12种为广布种以外,共有6种区系成分,其中中亚细亚种为最多,有87种,占已种的32.7﹪;其次依次为中央亚细亚种和特有种,分别为81种和65种,各占已知种类的30.5﹪和24.4﹪;泛古北种12种,占4.5﹪;欧洲西伯利亚种7种,占2.6﹪;欧洲中亚种最少,仅有2种,占0.75﹪,并根据新疆拟步甲科昆虫区系成分分析了其起源问题; 3)新疆拟步甲科昆虫的地理分布表明,分布于准噶尔盆地的种类最为丰富,计161种,占新疆已知种的60.5﹪;其次是塔里木盆地92种,占已知种的34.6﹪;东疆诸盆地63种,占23.7﹪;伊犁谷地56种,占21.1﹪;在三大山系中,天山山系的拟步甲种类最多,为54种,占20.3﹪;阿尔泰山山系28种,占10.5﹪;昆仑山山系13种,占4.9﹪。

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