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Here, using a strategy of re-expressing key developmental regulators in vivo, we identify a specific combination of three transcription factors Ngn3 (also known as Neurog3 Pdx1 and Mafa that reprograms differentiated pancreatic exocrine cells in adult mice into cells that closely resemble beta-cells.

这里,在体内通过一种策略将生长发育中关键的调控因子进行再表达,我们鉴定出了一系列3个转录因子(Ngn3 (亦称 Neurog3),Pdx1 和 Mafa),将它们重组入成年小鼠的胰腺外分泌细胞,相应的细胞可分化成类似于β细胞的细胞。

It seems that the consequence of cell spreading onto suitable surface were correlated to its secreting.

据此得到但尚需深入验证的试探性结论是,在没有外来化合物的干预下,细胞在适宜表面上的铺展活动与其向外分泌物似是相关的。

The team injected a cocktail of three viruses into the pancreases of adult mice. The viruses primarily infected the exocrine cells, and each one carried a different gene known to play a role in beta cell development.

研究组在成年老鼠的胰腺内注入了一种含有三种病毒的鸡尾酒,这些病毒主要感染外分泌细胞,每一个携带一种已知的在β细胞发展过程中起着不同作用的基因。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。