外-斐反应

The influence of different reaction conditions on the synthesis of chrysotile nanotubes was studied by means of infrared spectrometry, scanning electronic microscope and transmission electronic microscopy.

利用红 外吸收光谱、扫描电镜和透射电镜系统地研究了水热反应中，反应温度、Si/Mg比、反应时间等不同反应参数对合成纤蛇纹石纳米管的晶体生长及其结构的影响。

EDD and NEDD of external iliac artery in vivo (measured with high-resolution ultrasound), serum lipids, NO, NOS, plasma ET, ADMA, symmetric dimethylarginine and L-arginine, the area of AS plaque in thoracic aorta (dyeing with Sudan Ⅳ), the degree of AS lesion in abdominal aorta and external iliac arteries, NOS activity on the wall of the abdominal aorta, the expression of iNOS mRNA and eNOS mRNA on the wall of the abdominal aorta and the contractive and dilatant functions of abdominal aorta and external iliac arteries in vitro; B. the activities of dimethylarginine dimethylaminohydrolase in kidney (including the establishment of the determining method). 3. In the third part of the study, normal aorta strips were used. The following were surveyed: their response to using ADMA alone, influence of treating with ADMA, intervention of polydatin, influence of using ADMA and PD together on Emax and Kd that were contracted by PE.

第5组为未给药组。2、观察指标：A、各组髂外动脉EDD和NEDD、血脂、血清NO和NOS活性、血浆ET、ADMA、SDMA和L-精氨酸水平、胸主动脉AS斑块面积、腹主动脉和髂外动脉AS病变积分、腹主动脉壁NOS组织化学染色和eNOS mRNA和iNOS mRNA表达及离体腹主动脉与髂外动脉舒缩功能。B、各组兔肾DDAH活性。3、离体做正常主动脉条对单用ADMA的反应、PD和ADMA对PE收缩效应的影响及PD预处理对受ADMA作用的正常主动脉条PE收缩反应的影响(包括对Emax和Kd值的影响)。

This paperindicated that it was good for condensation reaction when benzene-ring bearingelectron-attaching groups. It also showed that and the 6-hydroxyl group could bereacted with acyl halide, haloid ether and halo alkene, but not with halo alkane. It wasnot only the first time to find that the reaction product of D-mannitol and aromaticaldehyde is tri-condensation derivatives, but also the first time to obtain thep-phthaldehyde-sorbitol derivatives containing eight hydroxyl groups.

研究发现：苯环上有吸电子基团时对缩合反应有利；多元醇缩醛衍生物6-羟基除与酰氯反应外，也能和卤代酸酯、溴代烯反应，但不与卤代烷反应；首次发现D-甘露醇与醛反应主要得到三缩合物；首次合成了含有8个羟基的对苯二甲醛和山梨醇的缩合物。

In this thesis, we describe a facile and economical synthesis of-abscisic acid from keto-isophorone and 3-butyn-2-ol through ketalization, oxidization, Witting-Horner reaction, reduction with chromium sulfate and other steps in 13% total yields. Compared to the previous routes, the starting materials are more commercially available and cheaper and the synthetic process is more easily controlled in our method, but the yield of this route is still to be improved.As to isostere principle, cyclopropyl and methyl vinyl are a couple of isostere.

本论文设计并完成了一条全新的外消旋脱落酸(1)全合成路线，从廉价的工业原料氧化异佛尔酮和丁炔醇出发，经过缩酮化反应、氧化反应、Wittig-Horner反应、CrSO_4选择性还原反应以及水解等七步反应实现了脱落酸的全合成，总产率达13％，与以往路线相比，该路线所用试剂廉价、合成路线简单，但产率有待提高。

We didn\'t find activated points in cerebellum and deeper brain.3.Acupuncture of sham point can significantly activated BA2,6,8,13,21,37,40,44,45,47,putamen and other areas.Both the left and right side of the brain have activated points,but points on the right side are more than those on the left.Both sides of middle temporal gyms,parietal lobule,supramarginal gyms and the lentiform nucleus have obvious activated points.The activated points mainly concentrated in the cerebral cortex,the deep-activated are mainly in the putamen.4. Sham needling in sham point can significantly activate BA6, 8,9,10,18,21,37,40,43,44.The activated points are mainly distributed in the right side of the brain.The left side also has some activated points;5.In the comparasion of Acupunture and sham-needling in S J5,we find that BA8 and cerebellum have distinct regional activated points;6.In the comparasion of acupuncture in SJ5 and sham point,we find BA2 and left cerebellar regions have activated points;7.Sham needling in S J5 compared with sham point,we find BA7,8,9,18 and other areas have activated points,the main activated points are at the left brain.It is not difficult to find that the distribution of activated points are mainly in the middle brain,no obvious activated points at the temporal lobe.

结果：通过对数据的处理和分析，我们初步发现：1、外关穴真针刺能显著激活Brodmann area45、37、44、40、22、13、37、47区、海马、杏仁核、黑质等区域，小脑左侧更明显，左侧颞叶皮层激活点多于右侧，且脑部左侧深层激活点多于右侧；2、外关穴假针刺能显著激活BA46、44、41、13、40、37、19区等区域，激活点主要集中表现在大脑皮层，以颞叶为主，小脑及深部未发现明显激活点；3、非穴真针刺组结果分析初步表明，BA2、6、8、13、21、37、40、44、45、47区以及壳核等区域有激活点，大脑左、右侧均有激活点，但右侧更多，双侧颞中回、顶叶下小叶、缘上回及豆状核有明显激活点，激活点主要集中在大脑皮层，深部激活点主要在壳核；4、非穴假针刺能显著激活BA6、8、9、10、18、21、37、40、43、44区等区域有激活点，主要分布在大脑的右侧，左侧也有不少激活点，就其具体分布主要在颞叶和额叶，少部分分布在顶叶和枕叶；5、外关穴真针刺与假针刺对比发现，BA8区和小脑等区域有明显的激活点；6、外关穴真针刺与非穴真针刺对比发现BA2区、左侧小脑等区域有激活点；7、外关穴假针刺与非穴假针刺对比发现，BA7、8、9、18等区有激活点，主要反应点在左侧大脑的枕叶中回、楔叶，顶叶楔前叶及额上回、中回，就其分布不难看出主要在大脑中部，颞叶未见明显激活点。

Result: the clinical therapeutic effectof experimental group, was more significant than control group who only underwent external radiation or afterloading intracavitary radiotherapy ,and the adverse reaction of control group exe; the radiation proctitis was more significant than experimental group; compare,58 cases in the experimental group complete the radiotherapy successfully.

结果：58例直肠癌病人采用外照射加后装腔内放疗的治疗效果优于单纯外照射或后装腔内放疗，其临床不良反应，特别是放射性直肠炎，较单纯外照射明显。实验组通过中药保留灌肠清洁肠道、温水坐浴等整体护理，不良反应较未采用整体护理的对照组明显减少， 58例病人均能按计划完成放射治疗。

The study suggested that TNF〓 and IL-1〓 might be produced in the cascade of events resulting in Wallerian degeneration and hyperalgesia following peripheral nerve compression, and increased TNF〓 and IL-1〓 mRNA may trigger other later responses in nervous system contributing to the initiation of peripheral neuropathic pain or other degeneration/regeneration processes.

提示：外周神经受压后诸如华勒氏变性、痛觉过敏等一系列反应可能有TNF〓和IL-1〓的产生，而后者的增加又会启动其它神经反应而在外周神经源性痛形成和神经退变/再生中发挥作用。

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Methods 100 examples,randoms choosing scheduled time line underbelly operation (operation,the womb cut completely or satisfy time eager operation,ovary tumour operation including cutting the palace product open) divide into two set,a forms:give hard film outside rentaini 0.4 mg + 0.75% bupivacaine 20 ml formulating cheng 100 ml analgesias,b group behind the skill:100 ml compounding cheng ease pain,comparatively,the life body collects,optesthesia simulates grade and bad reaction in giving hard film outside rentaini 0.4 mg + interest rate of 0.75% bupivacaine 20 ml + fluorines pai many 2 ml after the skill.results two set of patient skill queens circulation stabilizes equally,skill queen vas difference has no statistics significance,two set of analgesic effects have no notable difference,b many by-reaction of fluorine pai benefit appears on group but.

择期行下腹部手术(包括剖宫产手术、子宫全切或次全切手术、卵巢肿瘤手术)100例，随机分成两组，a组：在术后予硬膜外芬太尼0.4mg+0.75%布比卡因20 ml配制成100 ml镇痛。b组：在术后予硬膜外芬太尼0.4mg+0.75%布比卡因20ml+氟哌利多5mg配制成100ml镇痛，比较生命体征、视觉模拟评分和不良反应。结果两组患者术后循环均稳定，术后vas差异无统计学意义，两组镇痛效果无显著差异，但b组出现氟哌利多不良反应。

The reasons for false-positive facet blocks are multifactorial and include placebo response (18–32%) to diagnostic facet interventions, use of sedation, the liberal use of superficial LA, and the spread of injectate to paingenerating structures other than those targeted.166 Although some investigators have disputed this assertion,167,168 it is our belief that not only opioids, but sedatives such as midazolam, can lead to false-positive blocks by interfering with the interpretation of analgesic response (i.e., preventing a patient from engaging in normal activities) and virtue of their muscle relaxant properties.169 In a recent survey conducted in 500 patients receiving facet blocks or epidurals at an outpatient spine center, only 17% requested sedation.170

小关节阻滞性诊断的假阳性结果的原因是多种多样的，包括安慰剂反应(18–32%)，如利用镇静剂，浅表大量应用LA以及注射液外渗到目标外的其他疼痛发生阻滞。虽然有些学者对这种论断持怀疑态度，但是我们认为不论类罂粟碱，咪达唑仑等镇静剂，都可因具有麻醉反应（如可阻止患者从事正常活动）及肌松特点而导致假阳性率。在最近一项500人的研究中，这些门诊患者接受了小关节阻滞或硬膜外阻滞，只有17%患者需要镇静剂。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。