夏季

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis. CA inhibition may not be an important contributor since CA II expression and CA activity was intact in anhidrotic mice treated with topiramate.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

This might be one of the reasons that caused the rain belt anomalously southward for the summer of 1997 and 1999. In addition, the phase-locked west and south wind phases of the 30-60 day low-frequency oscillations happened together made obvious contributions to the heavy rainfall to the south of the Yangtze River Valley.

另外，在中国东部30°N及其以南地区，30～60天低频振荡的西风和南风位相锁相的叠加，对这两年夏季长江流域及其以南地区的降水做出了贡献。

The flowers of three species were bisexual, tetradynamous and the anthesis of each flower was about 1 to 3 days.

三种植物短的生活周期是逃避准噶尔荒漠夏季干热气候的一种适应对策。

The content of anthocyanin is higher in spring and autumn.

春秋两季花青苷的含量较高，而叶绿素含量则是在夏季最高。

In those years, anticyclone circulation prevails in Northern China with ridge to the western side of Beijing.

北京及附近地区位于低压槽区或处在东高西低的下游"阻塞"形势，是北京夏季多雨的基本环流条件。

In the spring and summer, a high pressure anticyclone system dominates the north Pacific Ocean, causing air to spiral out in a clockwise fashion.

在春季和夏季，一个高气压系统的压力控制着北太平洋，造成空气失控顺时针时尚。

Tropical eastern Indian Ocean and western Pacific Ocean ; cross equator flow ; Australia anticyclone ; circulation system ; summer

热带东印度洋—西太平洋海域；越赤道气流；澳洲大陆冷性高压；环流系统；夏季

According to the number of the current belt in the area, it is deduced that about 2 anticyclonic eddies, that is 2 clockwise sub-circulation systems, may occur every summer.

根据东、西向流带的数目推论，在该海域各年夏季可能存在2个反气旋涡旋，即呈现2个顺时针次级环流系统。

The lower-level (850 hPa) ISO pattern is char-acterized by an anticyclonic circulation over the area south of the Changjiang River, the South China Sea, and the Western Pacific, and a cyclonic circulation from the area north of the Changjiang River to Japan.

对逐年夏季的分析表明，无论当年东亚夏季风强与否，在所划分的几个东亚季风区所有涝的年份里，太平洋同一纬带上大气ISO向西传播都明显较强，而在这些区域绝大多数旱的年份里，相应的ISO向西传播明显较弱。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。