复发的

The cognition for the mechanism and treatment of recurrence and metastasis has changed with the introduction of the cancer stem cell theory, which provides a new pathway to the control of the cancer recurrence and metastasis.

随着肿瘤干细胞学说的提出及确认，人们对肿瘤复发、转移机制和对策有了新的认识和期望，从而为恶性肿瘤治疗后的复发转移的预防提供了一个全新的途径。

Results 206 example patients after the stomach big excision method, including 28 people to have the complication, the complication distribution are as follows: Falls the syndrome 5 casses; The duodenum remnant end bursts 4 casses; After ulcer recrudescence, the stomach evacuation barrier, the technique obstruct, the denutrition each 3 casses; After the technique bleeds, remnant stomach cancer each 2 casses; The alkalinity returns flows gastritis, the diarrhea, lips heal fistula each 1 example.206 example patients carry on the technique effect evaluation after the Visk graduation standard, among Ⅰ Level 80 casses,Ⅱ Level 102 casses;Ⅲ Level 14 casses;Ⅳ Level 10 casses.

手术人员一方面必须非常熟悉胃十二指肠及其临近器官的正常解剖结构，并在此理论基础指导下进行手术，另一方面还必须具备扎实过硬的操作和对病人高度负责的职业态度，这样才可能尽量避免术中邻近脏器的损伤和线结被剪断，术后缝线脱落，以及减少出血等情况的发生。在施行胃大部切除术时，对切除胃的范围还没有一个精确的定量手段，只能根据临床经验进行掌握。胃切除过多，术后会导致病人胃肠功能不足，出现营养不良，甚至可以出现粒细胞减少而引起腹泻。切除胃过少又可能达不到治疗目的，出现原发病的复发，如溃疡复发，残胃癌等。

Correlation of histotypes of phyllode tumor with local recurrence and tumor death was statistically significant at a level of P＜0. 001; correlation of infiltrative growth of the tumor with local recurrence was statistically significant at a level of P＜0. 001. Tumor necrosis and mitotic activity were independent prognostic factors.

叶状肿瘤的病理组织学等级与肿瘤的局部复发和因瘤死亡有统计学线性关系(P＜0.01)；肿瘤的浸润性生长方式与肿瘤的复发有线性关系(P＜0.01)；肿瘤性坏死和核分裂数值是独立的预后因素；术式等11个临床病理因素为单风险预后因素。

"We suggest a regular, simple urethral dilation protocol for patients with recurrent bulbomembranous urethral stricture shorter than 2 cm, because this significantly allays the stricture recurrence rate, possibly eliminates the need for consecutive DVIU, and reduces morbidity," the authors write.

作者认为，对复发bulbomembranous的尿道狭窄小於2 公分的患者，最好有一个常规且简单的尿道扩张方法，因为可以显著减少尿道狭窄的复发率，可能还可以减少DVIU治疗的次数而减少发病率。

"We suggest a regular, simple urethral dilation protocol for patients with recurrent bulbomembranous urethral stricture shorter than 2 cm, because this significantly allays the stricture recurrence rate, possibly eliminates the need for consecutive DVIU, and reduces morbidity," the authors write.

作者认为，对复发bulbomembranous的尿道狭窄小于2 公分的患者，最好有一个常规且简单的尿道扩张方法，因为可以显著减少尿道狭窄的复发率，可能还可以减少DVIU治疗的次数而减少发病率。

Iwa Kong of the University of Toronto.

加拿大多伦多大学的Iwa Kong博士报告指出，年龄在45～50岁女性患者组12%的复发率与此前报道的50岁以上女性患者在癌症确诊后10年内10%～15%的复发率相似。

Objective To investigate the patterns of mesorectum lymph node mestastases of rectal cancer. Methods From September 2004 to September 2005, the total lymph nodes was examined by pathology and immunohistochemical staining.

结直肠癌发病率位于恶性肿瘤第三位，虽然目前的治疗较过去有了相当大的提高，但复发和转移仍然是治疗失败的主要原因，即使常规病理学检查未发现淋巴结转移的结直肠癌病人中5年内肿瘤复发率也可达到50％[1]。

Furthermore, preliminary work also performed to examine whether PI3K/AKT signal transduction pathway was activated in the process of refractory leukemia development. Materials and methods An immortalized human bone marrow stromal cell line, HS-5, was introduced to establish a bi-phase culture system for the cultivation of B-lineage precursor leukemia cells. ELISA and RT-PCR were used to investigate the expression of VEGF and its receptors in the leukemia cell lines and primary childhood leukemia cells in different treated groups. Flow cytometory method and immunofluorescent staining were employed to examine the apoptosis signals both in the VP16 treated and untreated leukemia cells. Western blot was utilized to explore the PI3K/AKT activated status in the drug induced or uninduced leukemia cells and lymphocytes from healthy donors.

材料和方法使用来源于人类骨髓基质细胞的细胞株HS-5作为滋养层细胞进行急性淋巴细胞性白血病细胞的体外培养，通过细胞生物学和免疫学方法评估培养体系并鉴定出难治性白血病细胞克隆；以ELISA和RT-PCR方法检测急性白血病细胞株和患儿白血病细胞VEGF及其受体的表达，了解不同治疗阶段VEGF及其受体的表达状况，并结合临床指标进行分析，明确VEGF及其受体在白血病发生过程中的作用；流式细胞仪和免疫荧光染色法对正常健康儿童、初发白血病患儿、复发白血病患儿及缓解后患儿进行凋亡因子检测和分析，初步阐明难治性白血病抗凋亡形成的原因；蛋白印记分析检测PI3K/AKT信号传导通路在健康儿童、初发白血病和复发白血病患儿的表达，初步了解难治性白血病形成的分子生物学机制。

Results Aven mRNA expression was found to be higher in patients =10 years old and wasalso significantly higher in relapsed patients.

结果年龄大于10岁的ALL患者，Aven的表达明显高于年龄小于10岁的ALL患者，对于复发患者，Aven的表达亦明显高于未复发者。

People have paid attention to the pollution of soil and water quality caused by using organic arsenic chemistry reagent to prevent and cure apple-tree canker in our apple area, so it has an important purpose to seek a harm-free way for sustaining development of apple. The tests studied the effect of prevention and cure on apple-tree canker with EM mud, EM liquid, 40%'Fumeishen powder' and contrast. The results showed that the EM mud was superior to the EM liquid, 40% 'Fumeishen powder' and contrast. The prevention and cure effects of EM in 2006 and 2007 were 92.7% and 93.5%, while the recurrence rates of canker scars 1.8% and 2.8% respectively. And the healing effect of scar is 50.4%. So, it was considered as a new way to prevent and cure apple-tree canker with EM mud.

中国各苹果主产区果农长期使用有机砷等化学制剂防治腐烂病，对土壤、水质等环境造成的污染已引起人们的关注，寻求无公害的方法防治腐烂病，对苹果业可持续发展具有重要意义；本试验设EM活性菌泥涂抹、EM活性菌液涂抹、40%福美砷可湿性粉剂50倍液刮涂和对照（只刮除腐烂病疤，不涂药）4个处理，三次重复，进行了苹果树腐烂病的防治研究；结果表明，EM活性菌泥在防治效果、病疤复发率和促进病疤愈合效果方面均优于其它处理，其当年和第二年4月的防治效果分别为92.7%、93.5%，病疤复发率分别为1.8%、2.8%，促进病疤愈合效果也最好（50.4%）；因此，作者提出，将EM活性菌融入粘泥载体中制成菌泥，涂抹在腐烂病疤上，以菌治菌，是防治苹果树腐烂病的新途径。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。