处方

Methods The scutell aria and phellodendron were identified by thin layer chromatography and the content of berberine hydrochloride was determined by thin layer chromatography scanning.

采用薄层色谱法对处方中的黄柏和大黄进行定性鉴别；用薄层扫描法测定黄柏中盐酸小檗碱的含量。

Thermal analysis technique is widely used in preformulation work with advantages of simplicity and effectiveness.

地红霉素肠溶制剂，特别是微丸，应包制隔离衣以提高药物的稳定性；热分析技术应用于药物与辅料相容性的研究，操作简便，不需特殊制样，是处方前研究的有效的技术手段。

We carried out the preformulation study in incision of sustained release and bioadhension and followed the introduction of pharmaceutical necessity.

把该剂型的粘附性和缓释性作为两个基本切入点，导入剂型设计的需要，进行了处方前研究。

During the preformulation study, a great deal of transdermal enhancers in different styles was chosen to study the transdermal permeability of OXA in vitro.

在处方前研究中，选用大量不同类型的化学促渗剂进行药物体外渗透性研究。

In the preformulation study, the HPLC method for the analysis of RSP was established firstly and RSP solubility in various vesicles such as water, 20%PEG400, series of ethanol and propylene glycol was determined.

在制剂开发的处方前研究工作中，首先建立了利培酮HPLC分析方法，测定了药物在生理盐水、20%PEG400、各系列浓度的乙醇、丙二醇等溶媒中的溶解度。

ACD/Labs creates innovative software packages that aid chemical research scientists worldwide with spectroscopic validation of structures, chromatographic separation, medicinal chemistry, preformulation of novel drug agents, and chemical patenting and publication.

它研制出创新的套装软件，在以下方面给全世界的化学研究科学家提供帮助：结构的光谱验证，色谱层析分离，药物化学，新特药制剂的处方设计前工作，以及化学品专利和公布。

In the preformulation study, the ultraviolet spectrum and HPLC methods for the assay of α-asarone were established firstly and then the physicochemical properties, especially the octanol/water partition coefficient and the solubility in various solvent systems such as alcohol, PEG 400, IPM, octanol were examined. The prediction permeability was then compared with actual transdermal parameters obtained from the in-vitro diffusion study , and feasibility of drug transdermal absorption was then analyzed.

在制剂开发的处方前研究工作中，首先建立了α-细辛醚的紫外及HPLC分析方法，测定了药物的油水分配系数及在生理盐水、各系列浓度的乙醇、PEG400、肉豆蔻酸异丙酯、正辛醇等溶媒中溶解度；其次，确立了药物体外经皮渗透研究的方法，并考察溶媒及促渗剂(乙醇、丙二醇、肉豆蔻酸异丙酯等)对药物体外经皮渗透性能的影响，计算药物经皮渗透的各参数，根据药物的药物动力学参数，分析了药物经皮吸收的可行性。

In the preformulation studies, UV absorption characteristics, solubility and stability of the drug in the different media were determined, the physico -chemical compatibility between the drug and nine kinds of excipients was observed using DSC analysis.

在处方前研究中，对盐酸尼卡地平的紫外吸收特性、不同介质中的溶解度和稳定性进行了测定，并利用DSC法考察了该药物与九种辅料（EC，HPMC，PVP，PEG6000，MCC，乳糖，淀粉，硬脂酸镁，SLS等）间的物理化学相容性。

The main three parts of the present study are: the preformulation study involving screening the proper enhancers for transdermal aborption of α-asarone;Formulation study and developing a drug-in-adhesive transdermal patch of α-asarone using Eudragit E100 as pressure sensive adhesives;The α-asarone reservoir patch was prepared using 1 %HPMC of ethanol solution as medium and EVA membrane for controling the release of drug, and do the research its bioavailability.

主要内容有以下三个方面：药物经皮吸收制剂开发的处方前研究工作；采用Eudragit E100为压敏胶材料，进行了α-细辛醚胶粘剂分散型贴片的研究；以1%的HPMC的醇性溶液为储库介质，以EVA膜为控释膜，进行了α-细辛醚储库型贴片和生物利用度的研究。

RS were respectively used to prepare the ibuprofen pellets and the pseudoephedrine hydrochloride pellets by fluidized-bed technology.

RS为骨架和包衣材料制备盐酸伪麻黄碱缓释微丸，并运用统计软件SPSS进行处方和工艺的正交设计优化。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐