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The growth inhibiting rate of T24 cell lines were detected by MTT methods, apoptosis of cells were detected by flow cytometry, the mechanism of apoptosis was analyzed by detecting the protein expression of Bcl-2, Bax, Caspase-9, Caspase-3 and cytoplastic protein Cytochrome C. 4 We injected live T24 cells into the subcutaneous space of nude mice and successfully built up the animal model of bladder carcinoma. The effect of CS-PAA-EPI polymer magnetic microspheres targeting chemotherapy was investigated by HE staining, TUNEL ,tumor weight and volume inhibition rate. Results: 1 TEM revealed that the CS-PAA polymer magnetic microspheres were regular spherical shape,the average diameter was 80nm in dry condition. By controlling the pH value of the medium,polymers had positive or negative zeta potential. VSM showed the CS-PAA polymer magnetic microspheres had superparamagnetic. The diameter of CS-PAA-EPI polymer magnetic microspheres were 200nm in solution by DLS examining,the embedding ratio was 20%,the EPI loading rate was 15%, which was higer than reported in other articles. 2 Raw eye observation found that the rat"s bladder of treatment group was brown color,which meaned the aggregation of iron particles, compared with the control group, iron stain found iron particles were assembled in rat"s bladder of the treatment group, the amount of iron particles in liver and spleen were less obviously.

研究结果:1合成的CS-PAA磁性聚合物微球呈球形,大小均一,TEM测定其干态下粒径为80nm左右,磁化曲线证实具有超顺磁性,具有一定的PH敏感性,固载表柔比星后,水溶液性状稳定,无沉淀物,DLS测定直径约200nm左右,测定载药率为15%,较文献报道高,包封率为20%。2肉眼观察试验组大鼠膀胱表面呈褐色,可见大量的Fe粒子聚集,普鲁士兰染色法显示,试验组大鼠膀胱内有大量的Fe粒子,分布至膀胱全层,与对照组大鼠相比,试验组大鼠的肝、脾内的Fe粒子聚集量明显降低;HPLC测定结果与Fe染色相同;高剂量磁性CS-PAA-EPI生理盐水组及单纯EPI生理盐水组均在给药后14天出现血肌酐和尿素氮的升高,其他组大鼠血生化指标没有明显变化。3MTT法发现,高、中、低剂量磁性CS-PAA-EPI生理盐水组在外加磁场的协同作用下杀伤T24细胞效应明显高于单纯的EPI生理盐水组,FCM发现试验药物组可引起明显的肿瘤细胞凋亡,试验药物治疗组细胞胞浆内出现了由线粒体释放出的细胞色素C,试验组细胞Bcl-2蛋白减少,Bax蛋白变化不明显,Caspase-3、Caspase-9蛋白受到了激活活化。4高、中、低剂量磁性CS-PAA-EPI生理盐水组的瘤重抑制率和瘤体积抑制率均明显高于单纯的EPI生理盐水组(P<0.01),其中高剂量组的抑制率最高。

Numerical experimental results showed that the perimeter air deflectable deposited burner could ensure the flame stability to satisfy combustion requirements under low load and can prevent spout fire carrying, low concentration of particle matters around the water-wall ensures the water-wall to be in oxidation atmosphere to solve problems of high temperature erosion and slagging, and particle matters separated from main spray caused by deflectable deposited perimeter air plays a significant role in low NO combustion control.

数值试验结果表明,偏置周界风燃烧器在保证煤粉气流着火稳定性以满足低负荷燃烧要求的同时,具备较强的防止喷口带火能力;炉内水冷附近颗粒物质量分数相对较小,从而能保证较高的氧化性氛围以解决水冷高温腐蚀、结渣等问题;偏置周界风所引起的炉内气固两相偏析在低NO燃烧控制方面具有重要意义。

The numerical experimental result indicated that perimeter air deflectable deposited burner could ensure the flame stability, prevent spout fire carrying and promote low pollutant emission combustion.

结果表明偏置周界风燃烧器在保证煤粉气流着火稳定性同时,具备较强的防止喷口带火能力及低NOx燃烧能力,并能够保证了水冷附近处于相对较高的氧化性氛围,从而解决水冷高温腐蚀、结渣等问题。

In course of boiler operation, there is magnetic film formed on the wall of boiler, the electron move between the wall of furnace and water, causing debris such as calcium and magnesium ions is not easily pasted on the wall, as a result, it is not easy to scale, we do not need to demineralize water.

不易结垢,无需软化,锅炉运行过程中在管上形成磁膜,电子在炉和水之间运动,致使钙镁离子等杂物不易在炉贴后,从而不易结垢,无需进行软化水处理。

The superior wall of cavernous sinus was formed by two layers: superficial dural layer and deep layer.

的硬膜由浅、深两层组成,分别与外侧的浅、深层相延续。

Physiological indexes of drought-resistance, namely the four water parameters of osmotic potential at the turgor loss pointπ(subscript p, water potential at the water saturation point (π0), bulk modulus of elasticity, and the rate of bound water in cells V(subscript p/V0, for the three fire resistant trees, Schima superba, Cyclobalanopsis glauca, and Elaeocarpus glabripetalus, were studied using the pressure-volume technique.

应用压力-容积分析技术测定了木荷Schima superba,秃瓣杜英Elaeocarpus galbripetalus和青冈Cyclobalanopsis glauca等3个防火树种春季、夏季和秋季的水分特征参数,即初始质分离点渗透势π,饱和含水量时的最大渗透势π0,细胞弹性模数ξ,细胞质分离时的共质体水体积量与饱和时共质体水体积量之比V/V0。

There was no expression of CTGF protein in the pulmonary arteriole of the normal group, whereas, it was highly expressed in the tunica adventitia, slightly expressed in the endangium and rarely expressed in the tunica media of pulmonary arteriole in the hypoxemic group.

正常对照组大鼠肺小动脉CTGF蛋白未表达;低氧组大鼠肺小动脉外膜CTGF明显表达,内膜略有表达,中膜几乎无表达。

Methods Twenty-three cases of OSAS patients proved by polysomnography were examined with MRI. The cross-sectional area of retropalatal region, retroglossal region, epiglottal region and the lateral parapharyngeal fat pad of RP region was calculated. The thickness of bilateral and posterior pharyngeal wall and other indices were also measured. 30 nonsnoring age-matched normal subjects were selected as the control group. 15 patients underwent turbo field echo T1-weighted imaging during sleep. The images of RP, RG, and EPG were analyzed. Results In oSAS group, the cross sectional area of RP and RG regions was smaller than that of the control group.

应用MRI对23例经多导睡眠监测(polysomnography, pSG)确诊的OSAS患者及30例无打鼾的健康成人进行上气道检查,于轴面图像测量软腭后区(retropalatal region, RP区)、舌根后区(retroglossal region, RG区)和会厌区(epiglottal region, EPG区)的气道截面积,各区前后、左右径及其比值,各区咽侧、咽后软组织厚度,RP区咽旁间隙(lateral parapharyngeal fat pad,LPFP)截面积,于正中矢状面图像测量软腭厚度、长度及截面积,对两组各项检查指标进行统计学分析。

Methods By using knife chop up sebaceous gland cyst and resect skin and exenterate of cyst and keep down lower wall of cyst. Results All 113 cases patients has primary repair by using the method of one-stage operation.

用尖刀在波动最明显处切开囊肿,清理囊腔内容物,沿囊腔边缘和周围组织交界处将囊肿表面皮肤及囊全部切除,保留囊肿底

The ornamentation of exosporium varies from species.

苔藓孢子的外纹饰不同,一般认为孢子外光滑是进化性状,外上各种突起排列密集的则较为原始。

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In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是,在否定句或疑问句里,这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷

Nusa lembongan : Bali's sister island, coral and sand beaches, crystal clear water, surfing.

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