墩基

Oleanane-type triterpene with a carboxyl group at C-14 is present in a limited number of natural resources.

齐墩果烷型三萜与羧基在C - 14 ，是目前在数量有限的天然资源。

Pl. dies Architecture The dado of a pedestal, especially when cube-shaped.

dies 方形墩基：支柱的基座，尤其是立方形支柱

The primary studying works and characteristics:1 To summarize reinforcing theory of cement mixing pile composite foundation2 To analyze the primary mechanics characters and changing rules of cement mixing pile, based on analysis of test data both indoor and outdoor.3 To discuss siding frictional resistance, ending resistance, ultimate bearing capacity of simple mixing pile and effectiveness factor of grouped piles, loading ratio of soil between piles under cushion cap of grouped piles and stress ratio of pile and soil and so on, and use many computation method and experimentation method to ensure bearing capacity of mixing piles composite foundation.4 To point out and analyze eight sides flaws and problems of the bearing capacity calculation method of mixing pile compositefoundation which ensured by national and normative method/ formula.5 To apply test results of loading tests and a few settlement observation data, use gray theory to predicate ultimate bearing capacity of deep mixing piles, actual example demonstrate engaging between theoretical predicted value and actual value.6 To apply groovy layerwise summation method to discuss entity piles method, double foundation method, equivalent layerwise summation method and consolidation theoretical method and so on, especially by combination of engineering example, use FEM to calculate or discuss the settlement and changing rules of composite foundation.7 To discuss problems of critical length of composite foundation by combination of engineering example and numerical analysis method, and analyze the contrast of critical length between simple pile load and most area load of composite foundation, not only critical length of composite foundation is relative to modulus ratio between piles and soil, but also upside load distribution area of composite foundation.

主要的研究工作与特色为：(1)总结了水泥搅拌桩复合地基的加固原理；(2)在对室内外试验资料进行统计分析的基础上，系统分析了搅拌桩水泥土的主要力学特性及其变化规律；(3)探讨了搅拌单桩的侧摩阻力、端阻力、极限承载力及群桩效率系数、群桩承台下桩间土荷载分担比及桩土应力比等，提出用多种计算方法并结合试验方法来综合确定搅拌桩复合地基的承载力；(4)明确指出和分析了按国家有关规范的方法确定搅拌桩复合地基承载力所存在的八个方面的缺陷与问题；(5)利用过去没有加载至破坏阶段的载荷试验成果和较少的沉降观测数据，尝试了用灰色理论预测深层搅拌桩的极限承载力，实例表明理论预测值与实测值吻合较好；(6)在常规分层总和法的基础上，探讨了复合地基沉降计算的实体墩基法、双层地基法、等效作用分层总和法、固结理论法等，特别是结合工程实例，用有限元数值计算等方法计算和讨论了搅拌桩复合地基的沉降及其变化规律；(7)结合工程实例，用数值分析方法探讨了复合地基临界桩长的问题，指出和分析了单桩荷载下的临界桩长与复合地基大面积荷载下的临界桩长存在很大的差别，复合地基的临界桩长不仅与桩土模量比有关，而且与复合地基上部荷载分布面积有关。

Compound 9 is glycosylated in the presence of TMSOTf with rhamose-derived trichloroacetimidates to provide target trisaccharide Saponin 1, oleanolic acid 3-yl-2,4-di-O-a-L-rhamnopyranosyl -p-D-glucopyranosideCoumpond 18 is prepared with oleanic acid and Bromide 11 through phase-thansfer catalysis glycosylation manner.

三糖皂苷Saponin 1是以葡萄糖齐墩果酸皂苷为起始原料，用BBTZ(1-苯甲酰苯并噻唑)选择性保护葡萄糖3′，6′-羟基得到化合物9，然后以化合物9为糖基受体，进行一步糖苷化可以在化合物9的2′，4′-羟基上同时引入两分子鼠李糖，最后脱掉所有的保护基得到目标化合物Saponin1。

On the basis of spectral analysis, these compounds were identified as Kaempferol , Kaempferol-3-O-β-D-glucopyranoside , Kaempferol-3-O-β-D-galactopyranoside, Quercetin , Quercetin-3-O-β-D-arabinopyranoside, Quercetin-3-O-β-D-galactopyranoside, gallic acid, methyl gallate-4-O-β-D- galactopyranoside, caffeicacid, methyl caffeate, 4-cafeoyl-(3"a, 4"a, 5"β)- trihydroxyquinic acid, 3"-cafeoyl-(3"a, 4"P, 5"P )-trihydroxyquinic acid methyl ester, 5"-cafeoyl-galactonic acid , pumiloside, loganic acid , 5R,6S,7E-megastima-3-on-7-en-9-ol 9-O-β-D-glucopyranoside. 2a, 3β-dihydroxy-oleanoic acid , 2a, 3β, 23-trihydroxy-oleanoic acid, 3a, 6a-dihydroxy-oleanoic acid, 3β-hydroxy-ursoic acid, 2a, 3a, 23-trihydroxy-ursoic acid , 2a, 3β, 23-trihydroxy-ursoic acid, 2β, 3β, 19a -trihydroxy-ursoic acid, 2a , 3β, 19a -trihydroxy-ursoic acid-28-O-β-D-glucopyranoside , 2a. 3a, 19a-trihydroxy-ursoic acid-28-O-β-D-glucopyranoside, 2a, 3a, 19a, 23-tetrahydroxy-ursoic acid, 1a, 3a, 19a, 23-tetrahydroxy-ursoic acid-28-O-β-D-glucopyranoside , 3a, 19a, 23-trihydroxy-ursoic acid.

从珙桐中分离鉴定得到了28种化合物，它们分别是：山奈酚，3-O-β-D-吡喃葡萄糖基-山奈酚甙，3-O-β-D-吡喃半乳糖基-山奈酚甙，槲皮素，3-O-β-D-吡喃阿拉伯糖基-槲皮素甙，3-O-β-D-吡喃半乳糖基-槲皮素甙，没食子酸，4-O-β-D-吡喃半乳糖基-没食子酸甲酯，咖啡酸，咖啡酸甲酯，4-咖啡酰基-(3&α，4&α，5&β)-三羟基鸡纳酸，4-咖啡酰基-(3&α，4&β，5&β)-三羟基鸡纳酸甲酯，5'-咖啡酰基-半乳糖酸，pumiloside，loganic acid，5R，6S，7E-megastima-3-on-7-en-9-ol9-O-β-D-glucopyranoside，2α，3β-二羟基齐墩果酸，2α，3β，23-三羟基齐墩果酸，3α，6α-二羟基齐墩果酸，3β-羟基熊果酸，2α，3α，23-三羟基熊果酸，2α，3β，23-三羟基熊果酸，2β，3β，19α-三羟基熊果酸，2β，3β，19α-三羟基熊果酸-28-O-β-D-吡喃葡萄糖甙，2α，3α，19α-三羟基熊果酸-28-O-β-D-吡喃葡萄糖基甙，2α，3α，19α，23-四羟基熊果酸，2α，3α，19α，23-四羟基熊果酸-28-O-β-D-吡喃葡萄糖基甙，3α，19α，23-三羟基熊果酸。

Based on relative literatures,this part has included five resesearch aspects as below.1 Fifteen compounds were isolated and purified by extraction,column chromatography,and their structures were determined on the basis of spectral analysis: acteoside(Ⅰ-1),isoacteoside(Ⅰ-2),crenatoside(Ⅰ-3),cistanoside F(Ⅰ-4),sinapoyl-4-O-β-D-glucoside(Ⅰ-5),adenosine(Ⅰ-6),β-siterol(Ⅰ-7),oleanic acid(Ⅰ-8), succinic acid(Ⅰ-9),caffeic acid(Ⅰ-10),protocatechuic aldehyde(Ⅰ-11),p-hydro xybenzyl alcohol(Ⅰ-12),β-daucosterol(Ⅰ-13),D-galacitol(Ⅰ-14),D-mannitol(Ⅰ-15).Ⅰ-4～15 were obtained from this plant for the first time,andⅠ-6,7,9,and 13 were isolated from Orobanche genus for the first time.2 The scavenging test of DPPH showed that most compounds have comparative antioxidant activity as L-ascorbic acid and part of them show better activity such as the O.coerulescens extract and phenylethanoid glycosides.Acteoside showed potent free radical scavenging effects with a median inhibition concentration of 25.6μg/ml.3 The anti-HBV activities of acteoside,isoacteoside and crenatoside were measured,and all of them showed suppressive activity on the expression of HBsAg and HBeAg in the HepG2.2.15 cell line.

本论文在文献调研基础上对紫花列当化学成分及生物活性进行了研究，并从免疫抗病毒角度探讨紫花列当中特征性成分类叶升麻苷的肝保护作用及其机制。1采用大孔树脂、硅胶和Sephadex LH-20等色谱技术对紫花列当进行系统的植物化学研究，从中分离得到19个化合物，利用UV和NMR等波谱手段及理化性质鉴定了其中的15个化合物，分别为类叶升麻苷(Ⅰ-1)、异类叶升麻苷(Ⅰ-2)、crenatoside(Ⅰ-3)、cistanoside F(Ⅰ-4)、sinapoyl-4-O-β-D-glucoside(Ⅰ-5)、腺苷(Ⅰ-6)、β-谷甾醇(Ⅰ-7)、齐墩果酸(Ⅰ-8)、琥珀酸(Ⅰ-9)、咖啡酸(Ⅰ-10)、原儿茶醛(Ⅰ-11)、对羟甲基苯甲酸(Ⅰ-12)、β-胡萝卜苷(Ⅰ-13)、D-半乳糖醇(Ⅰ-14)和甘露醇(Ⅰ-15除化合物Ⅰ-1、Ⅰ-2和Ⅰ-3外，其余化合物均为首次从该植物中分离得到。2)通过大孔树脂富集该药材有效部位苯乙醇总苷，并采用HPLC测得其所含特征性成分类叶升麻苷的含量可达80%以上。3DPPH自由基清除试验显示紫花列当提取物及其所含的苯乙醇苷类化合物均具有较好的抗氧化能力，其清除DPPH自由基能力接近于抗坏血酸。4采用卡介苗整体致敏、脂多糖离体攻击构建大鼠原代肝细胞免疫性损伤模型，在体外观察类叶升麻苷的保肝作用。

ATA was found to exhibit more distinctive cytotoxicity toward human cervical squamous carcinoma HeLa cells than oleanolic acid, which suggested that the position of the carboxyl group significantly affects the cytotoxicity of oleanane-type pentacyclic triterpenes with a carboxyl group.

周晓华被发现展品更为鲜明的细胞毒性，对人体颈部鳞癌Hela细胞比齐墩果酸，这表明的立场与羧基显着影响细胞毒性的齐墩果烷型pentacyclic三萜类化合物与羧基。

Based on the 70 axial force monitoring data on 64 manometers in south tower piles foundation of JiangYin Bridge, the force transferring mechanism of socketed pile group using friction ineffective treatment at the top 20 meters was analyzed. The surcharge problem, the course of stress adjustment and the transition of the slip surface on which was easiest to slide in pile group were discovered.

根据江阴大桥南塔墩基桩轴力64个测点的70次观测成果，分析了桩周摩擦失效嵌岩群桩的传力机理，揭示了群桩中的超载问题和应力调整过程以及最不利滑面的迁移；采用理论计算、定性评价和数值分析相结合的方法首次建立了基桩轴力安全监控模型。

The design includes determination of size and details of twin post piers and footing, internal force calculation, bending rebar of pier capping beam, shear rebar and stirrup, compression bar for piers and footings. Check of bearing capacity of piers and piles, crack opening, lateral displacement of pier, and eccentricity, were also conducted.

设计主要内容：双柱式桥墩及基础细部尺寸拟定；内力计算，墩盖梁抗弯钢筋、抗剪钢筋和箍筋的配置及墩身和桩基抗压钢筋的配置；墩与桩承载能力检算、裂缝宽度检算、墩顶水平位移检算，偏心距检算。

The 120m3 BF foundation temperature is reduced from 950℃ to below 700℃ and the furnace life campaign is prolonged for more than 2 years by taking furnace maintenance measures such as batching schreyerite in burdens to deposit Tion hearth bottom to form a steady protective layer and make molten iron liquidity slower to slowdown the erosion on bottom, drilling holes to lay water-cooling pipes in heat resistant foundation to heighten the 1150℃ isothermal line of molten iron to make frozen metal layer thicker.

对济钢120m3高炉炉底侵蚀状况，在生产中配加钒钛矿，使其还原成Ti的沉积，以对炉底形成稳定保护层，降低铁水流动性，减缓铁水对炉底冲刷；同时在耐热基墩打孔，穿埋水冷管，促使炉缸铁水1150℃等温线上移，凝固团增厚。实践表明，特护期间炉基温度由950℃下降至700℃以下，炉役寿命延长2年以上。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失