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T stimulates not only the IL-2 dependent cell line CTLL-2, but also the activated T cells and the cytolytic T cells. It is also a T-cell chemoattractant.

L-15不仅可以维持IL-2依赖细胞株CTLL-2的生长,而且可以刺激T细胞的增殖及细胞毒T细胞的增殖,且是T细胞趋化因子。

In the late proliferative and secretive phases, expression of ERα in stromal cells significantly decreased to the level observed in the desquamative phase Differently, no clear expression of ERβ was detected in stromal cells in the late proliferative phase. However, its expression appeared again in the secretive phase.

结果显示: 1ERα和ERβ在恒河猴子宫内膜的上皮细胞、基质细胞中均有表达,其表达水平在正常月经周期中发生周期性变化:上皮细胞中两种受体的表达水平从增殖期开始逐渐升高,到增殖晚期最高;分泌期开始下降,直到月经期的水平。

TFC could remarkably inhibit the ear edema induced by dimethylbenzene in mice at the dose of 125,250,500mg.kg~(-1), the swelling of rats hind paws induced by carrageenan and primary inflammatory reaction in AA rats at the dose of 84,168,336 mg.kg~(-1) and reduce the weight of granuloma induced by cotton in rats at the dose of 84,168,336mg.kg~(-1), respectively.

TFC的免疫调节作用体外研究发现,TFC0.005,0.05,0.5,5,50 mg·L~(-1可明显提高环磷酰胺(cyclophosphamid,Cy)诱导免疫功能低下小鼠的脾淋巴细胞增殖反应,而对正常小鼠的脾淋巴细胞增殖无明显作用。

The results have indicated that the composition of the medium for Lactobacillus fermentum and Lactobacillus plantrum is 2% sucrose, 0. 5% peptone and 11% soybean powder.

在乳酸菌增殖培养的研究试验小,利用正交试验及混料回归试验,确定了增殖培养基的组成成分和各成分的配比,其最佳配方为2%蔗糖、0.5%蛋白胨、11.0%大豆粉。

Methods Human hemangioma endothelial cells cultured in vitro were injected hypodermically into nude mice(BALB/c nude mice). The volume of in the transplanted tumor was measured in 60 days. Samples were taken from survival tumor and stained immunohistochemically by CD31 and Ki-67 before subjected to histopathological examination.

将体外培养的血管瘤内皮细胞通过注射的方式植入裸鼠(BALB/c nude mice)皮下,测量不同生长时期瘤体体积变化,观察至60天后进行病理学光镜检查,并通过血管内皮细胞单克隆抗体CD31、细胞增殖标记抗体Ki-67免疫组化染色研究所成瘤体的同源性及增殖活性。

MTT assay indicated that anti-proliferative activities in HeLa, SHIN3, HOAC-21 and HAC-2 cell lines were closely related to structure, 1,10-seco of eudesmane sesquiterpene lactone resulted in reduced anti-proliferative activity. The anti-tumor activity of isoalantolactone was probably achieved by inducing HeLa cell apoptosis.

提示A-环开环可能是导致桉叶烷型倍半萜内酯的体外抑制肿瘤细胞增殖作用消失或减弱的原因;异土木香内酯抑制肿瘤细胞增殖作用有可能是通过诱导肿瘤细胞凋亡机制而实现的。

The process of osteoarthritis mesochondrium degradation is possibly attributed to the synergistical consequence of MMPs and other factors. Pilose antler peptide can promote the proliferation of OA chondrocytes of rabbits ,inhibit the overexpression of MMPs of OA chondrocytes.It can possibly play a effective role in the treatment of OA.

结论骨性关节炎软骨细胞在骨性关节炎发病过程中,软骨细胞正常分化及增殖发生改变;骨性关节炎软骨基质降解过程可能是金属蛋白酶与其它因子协同作用的结果;鹿茸多肽可促进骨性关节炎软骨细胞增殖,并可抑制骨性关节炎软骨细胞中金属蛋白酶的过度表达,可能对治疗骨性关节炎有较好的作用。

Methods: Using the techniques of cell culture ex vivo, flow-cytometry, immunocytochemistry, the effects of GPS on the proliferation of human promyelocytic leukemia cell line(HL-60) and human granulocytopoiesis and monocytopoiesis were observed.

结果:GPS在体外能抑制HL-60细胞增殖,而同等剂量的GPS能明显促进正常粒单系造血祖细胞的增殖分化;在本实验条件下未见GPS对HL-60细胞有明显的诱导分化作用。

Methods:The conservative region of mTOR gene was inserted into pLXIN reversedly, then the vector was packaged in PT67 cells by transfection with lipofectamine and transfected to VSMC. The efficiency of antisense inhibition was verified,and the changes of p70S6k and 4E-BP1 were also determined at the same time. The proliferation activity was determined by flowcytometry and MTT.

采用脂质体介导转染包装细胞后构建mTOR的反义重组逆转录病毒载体(pLXIN-AmTOR)感染VSMC,检测mTOR及其下游底物包括真核细胞启动子4E结合蛋白1(4E-BP1)和核糖体蛋白S6激酶(p70S6k)的表达变化,以及VSMC细胞增殖周期和增殖活性的改变。

The results were that PNWⅠ had a significant effect at the concentration of 200μg/mL and PNM had no significant effect on the splenocyte proliferation.

初步考察了PNW和PNWⅠ对小鼠体外淋巴细胞增值的影响,结果显示PNWⅠ在200μg/mL时对淋巴细胞有显著的促进增殖作用,PNW对淋巴细胞的增殖作用不显著。

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In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

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