增殖的

Abstract］ Objective To explore the effect of radiotherapy on the auxesis of Hela cell in cervix carcinoma to offer the theory elements to identify whether or not the cervix carcinoma would be treated by radiotherapy with non-routine segmentation.Methods After radiotherapy with different doses,the Hela cells changes of potential doubling time by cytometry with trypanblau coloration were analysed,and the livability of clonogenic cell at the same time was detected by clone,and the two former were combined to aralyse the changes.

目的 探讨放射对宫颈癌Hela细胞系再增殖的影响，宫颈癌是否有必要实行非常规分割放疗提供定的理论基础方法在不同剂量的放射作用下，以台盼蓝染色细胞计法分析Hela在照射后不同时间点的潜在倍增时间的变化；以克隆形成实验检测其同期克隆源性细胞存活比率，并将两者结合分析。

Abstract］ objective to explore the effect of radiotherapy on the auxesis of hela cell in cervix carcinoma to offer the theory elements to identify whether or not the cervix carcinoma would be treated by radiotherapy with non-routine segmentation.methods after radiotherapy with different doses,the hela cells changes of potential doubling time by cytometry with trypanblau coloration were analysed,and the livability of clonogenic cell at the same time was detected by clone,and the two former were combined to aralyse the changes.results （1）tpot shortening was observed in hela cell after radiotherapy.

目的 探讨放射对宫颈癌hela细胞系再增殖的影响，为宫颈癌是否有必要实行非常规分割放疗提供一定的理论基础。方法在不同剂量的放射作用下，以台盼蓝染色细胞计数法分析hela在照射后不同时间点的潜在倍增时间的变化；以克隆形成实验检测其同期克隆源性细胞存活比率，并将两者结合分析。

Cell cycle is the cell through a series of orderly changes in the cells to achieve cell growth and proliferation process of cell cycle regulation and individual development, differentiation, growth, regeneration, aging and cancer cells is closely related to eukaryotic cell cycle mitosis two key processes, namely DNA replication and sister chromatid evenly assigned to the sub-cells.

细胞周期是指细胞通过一系列有序的细胞内变化，实现细胞生长和分裂增殖的过程细胞周期的调控与个体发育、分化、生长、再生、衰老以及细胞的癌变密切相关真核细胞有丝分裂周期有两个关键的过程，即DNA的复制和姐妹染色体均衡地分配到子细胞中。

These culture conditions not only maintain the undifferentiated state and normal diploid karyotypes of BALB/c mouse ES cells effectively, but also maintain a series of their characteristics of murine stem cells. two different kinds of digestive methods and Two kinds of digestive juice with different concentrations were designed to dissociate proliferous inner cell mass and ES cell clonies deriver from dissociative ICM.

这一培养条件不但有效地维持了ES细胞的未分化状态和正常二倍体核型，而且维持了其作为多能性胚胎干细胞的一系列特征；实验设计了两种离散方法和两种浓度的消化液，用来离散增殖的ICM和ICM离散后出现的ES集落。

The journal publishes reviews covers the whole field of the biology and biochemistry of cancer, emphasizing oncogenes and tumor suppressor genes, growth-related cell cycle control signalling, carcinogenesis mechanisms, cell transformation, immunologic control mechanisms, genetics of human cancer, control of cell proliferation, genetic and molecular control of organismic development, rational anti-tumor drug design.

该杂志主要发表有关肿瘤生物学和生物化学的综述。其内容包括：致癌基因和肿瘤抑制基因，与生长有关的细胞周期控制的信号转导，致癌机理，细胞转化，免疫控制机理，人类癌症遗传学，细胞增殖的控制，组织发育的遗传和分子控制，合理的抗肿瘤药物设计等。

The effect of bavachin and corylin, two active principles from Psoralea corylifolia L., on UMR106 cyclin E expression by Western blotting was examined. The result showed that the two flavonoid compounds had no significant effect on cyclin E expression after various exposure time.

对于中药补骨脂中分离的两个促成骨样细胞增殖的活性成分补骨脂二氢黄酮和补骨脂异黄酮，采用Western blotting的方法考察不同时间对UMR106细胞周期蛋白cyclin E的表达，结果它们对cyclinE的表达没有显著影响。

The expression of Pax-6 gene in the different stages was demonstrated by RT-PCR (Real - Time PCR):(1) The mRNA of Pax-6 gene expression was positive in Bufo raddei Strauch embryo at 16 stage; and the gene expression was also detected at 20 stage.

2荧光定量PCR结果显示在花背蟾蜍的晶状体再生的第7天Pax-6基因的表达量达到最高，表明此时期Pax-6基因在晶状体再生的过程中起到调控细胞增殖的作用。

It is a little of expression in the physiological condition,while stronger expression under pathological.The high expression of glial fibrillary acidic proteinis a marker of activation of astrocyte.

GFAP的表达增强是Ast活化增殖的特征性标志，在神经系统发育及病理过程中发挥重要作用，对神经元的存活、突起的再生和神经系统功能的恢复有重要的影响。

The tumor is sessile, polypoid, or castlike and is characterized by the presence of innumerable papillary frondlike infoldings comprised of proliferations of columnar epithelial cells around the slender fibrovascular stalks that are supported by the connective tissue of the lamina propria.1 Occasionally, tumor spreads superficially along a variable length of the bile duct.

该肿瘤是无蒂、乳头样或脱落物样的，以及肿瘤表面特征性地存在无数乳头样叶状内折叠，这些乳头是由围绕纤细的以管腔的结缔组织为支撑的纤维血管茎增殖的柱状上皮细胞构成。肿瘤偶尔也会沿不同长度在胆管表面蔓延。

The transforming growth factor-β superfamily, a large group of highly conserved growth factors including TGF-βs, activins and BMPs, regulate a wide variety of cellular functions such as proliferation, differentiation, apoptosis and migration. Signals from these growth factors are transduced by a group of Smad proteins. To date, there are nine vertebrate Smads, including the receptor-activated Smads , Smadsl-3, 5 and 8, the common mediator Smad4 and Smad4β, and the inhibitory Smads, Smad6 and 7. Signaling is initiated when the ligand induces assembly of a heteromeric complex of type Ⅱ and type Ⅰ TGFβ receptors. Then R-Smads are directly phosphorylated by activated type I TGF-β receptors.

在多种SMADS中，SMAD5令我们产生兴趣，基于三个原因：1、Smad5基因敲除胚胎中发现卵黄囊的异位造血以及CFU-GM祖细胞数目增加，表明SMAD5可能是早期造血发育的负向调控基因。；2、应用反义核酸封闭Smad5可以逆转TGF-β对祖细胞增殖的抑制效应，表明它可能介导TGF-β信号转导，后者的异常，包括某些SMADS的功能异常，和白血病紧密相关；3、Smad5基因定位在人染色体5q21，此区域的缺失和急性髓系白血病和骨髓增生异常综合症相关，因此，Smad5被怀疑为白血病抑制基因。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。