增宽

Results Sacroiliac joints in 62 cases were abnormal:in early stage,articular face was affected and the bone cortex incrassated and osteosclerosis partly,joint space was normal;in late stage,vermiform destruction of bone was seen in articular face,the density of cortex was heighten irregular,joint space widen or narrow,and at last the joint space vanished,the joint ankylosed.

结果 62例患者骶髂关节表现异常，包括：早期，骨关节面受侵蚀、骨皮质局限增厚、硬化，关节间隙正常；后期，关节面呈虫蚀状改变，关节面皮质密度不规则增高，关节间隙增宽或变窄，最终关节间隙消失，关节强直。

After being treated with Nephritis NO.1 Prescription, NO and the ET-1 contents in Model group recovered(P〈0.05)2、Nephridial tissue examination indicated that there were lessened microscopic structural pathological changes ,cellular proliferation and widening mesangial region in mesangial cells through treatment compared to Model Control , Conclusions :1 For Mesangial Proliferative Nephritis , Manshen NO.1Prescription has satisfactory therapeutic effects, It can improve symptoms, restrain accrementition in intercapillary cells and mesangial region, thus prevent nephric tubule's indurascent and prevent renal failure.2、Manshen NO.1 Prescription can increase NO contents; reduce ET-1 contents in Model control.

结果：1、与正常对照组相比，模型组血清NO含量减低(P〈0.05)，而ET-1的含量升高P〈0.05〉，给予慢肾1号方治疗后，可明显提高系膜增生性肾炎模型组血清NO(P〈0.05〉，减低血清ET-1的含量P〈0.05〉，2、肾组织学检查显示：经慢肾1号方治疗后，与模型组相比，肾小球系膜细胞增生及系膜区增宽等超微结构病变均有所减轻。

Results 6 patients with PAP presented with ground-glass opacification of the bilateral lungs on HRCT. Typical chest HRCT scan showed "map-like" lesions in 3 cases and "cobble stone-like" lesions in 3 cases. Multifocal consolidative opacities in the lungs were seen on HRCT in 3 cases. Lung biopsies from 6 patients with PAP revealed a prominent positive periodic acid-Schiff intra-alveolar exudates. There were normal alveolar spetasis in 3 patients while interstitial thickening, fibroblast hyperplasia, interstitial fibrosis in the others.

结果 6例患者在不同层面可见磨玻璃影，其中2例可见小结节影；3例表现为两肺斑片状磨玻璃影与周围肺组织分界清楚，呈地图样改变；3例因磨玻璃影与小叶间隔增厚交织成铺路石样改变；3例可见肺泡实变融合成密度较高的斑片状阴影，1例在肺泡实变区可见&空气支气管征&。6例患者活检肺组织在光镜下显示肺泡腔内充满大量块状或颗粒状嗜伊红物质，PAS染色阳性，AB染色阴性，其中3例肺泡间隔正常，3例肺泡间隔增宽，可见慢性炎性细胞浸润、成纤维细胞增生和胶原沉积。

Posterior tilt angle was increscent and part epiphyseal line was narrow inside and wide outside for 7 cases.

其X线表现：骺线增宽或明显增宽者10例。后倾角增大，部分骺线内窄外宽者7例。

Resujts:① The distribution of lesions are mostly symmetrical, extensive, predominant in the middle and lower lung fields, and posterior areas in peripheral;② There are so many HRCT findings of lung, ILD is predominant: intralobular interstitial thickening 46 cases (100%), ground-glass opacity 41 cases (89.13%), peribronchovascular or centrilobular interstitial thickening 40 cases (86.96%), interlobular septal thickening 38 cases (82.61%), irregular linear opacity 37 cases (80.43%), small nodular opacity 34 cases (73.91%), subpleural line 27 cases (58.70%), bmnchiectasis or bronchiolectasis 19 cases (41.30%), patch opacity 18 cases (39.13%), expiratory mosaic sign 15 cases (32.61%), interface sign 14 cases (30.43%), honeycombing 12 cases (26.09%), emphysema or bulla 3 cases, cystic airspace suspected 1 case, and atelectasis suspected 1 case;③ Mediastinum and pleura: multiple small lymphonodi in mediastinum 41 cases (89.13%), pleural thickening or rough 38 cases (82.61%), esophagoectasis 11 cases (23.91%), unilateral little pleural fluid 1 case, and mediastinal emphysema 1 case.

结果：①皮肌炎肺部病变分布呈对称、广泛、偏中下、偏外后的特点；②肺部HRCT表现多样，以肺间质性改变为主：小叶内间质增厚46例(100%)，磨玻璃影41例(89.13%)，支气管血管束增宽或小叶核心增大40例(86.96%)，小叶间隔增厚38例(82.61%)，不规则纤维索条影37例(80.43%)，结节影34例(73.91%)，胸膜下线27例(58.70%)，支气管或细支气管扩张19例(41.30%)，斑片影18例(39.13%)，呼气相马赛克征15例(32.61%)，界面征14例(30.43%)，蜂窝影12例(26.09%)，肺气肿或肺大泡3例，单纯囊状气腔1例，肺不张l例；③纵隔及胸膜：纵隔小淋巴结影41例(89.13%)，胸膜增厚或毛糙38例(82.61%)，食管扩张11例(23.91%)，单侧少量性胸腔积液1例，纵隔气肿1例。

The results were expressed in mean±1SD. Pearson X~2 test and One-way ANOVA test were used. The data analyzed using the SPSS (version 11.5). Results: The sensitivity, specificity, positive and negative value of US for the LPEH model on the children cadaver were 88%, 84%, 79%, 91%, respectively. With regard to the thickness of femora head cartilage, the thickness of the anterior layer or posterior layer, there were no significant differences among three groups. However, the anterior layer was thicker than the posterior layer in three groups. The fluid in hip joint was detected in all of 21 symptomatic hips, which was clear commonly (90%) in early procedure. The amount of fluid in anterior recess showed a positive correlation with age (p .05). No fluid was detected in the asymptomatic and normal hips (2mm). The mean maximum width of inferomedial recess was significantly larger than that of anterior recess (12.50±4.04mm vs.4.35±0.8mm, p 0.05) in the symptomatic hip joints. The echogenic entrapped labral plicaes were demonstrated in the inferomedial recess in all of 21 children with LPEH, whose length and width ranged from 5.3mm-25.0mm (mean,15.6±5.6mm) and from 4.0mm-17.0mm (mean,8.9±7.8mm).

结果1，尸体LPEH髋关节模型的超声诊断敏感性、特异性分别为88％、84％，阳性预测值、阴性预测值分别为79％、91％。2，21例患儿的LPEH患髋(21侧)、健髋(21侧)，以及21例正常儿童健髋(42侧)的超声检查显示：髋关节周围软组织及股骨头无形态结构差别；股骨头软骨厚度无统计学差异(3.5±0.5mm vs.3.6±0.4mm vs.3.6±0.5mm，p＞0.05)；关节囊前层及后层厚度无统计学差异(前层厚度2.79±0.74 mm vs.2.56±0.40mm vs.2.56±0.72mm；后层厚度2.70±0.82mm vs.2.48±0.54mm vs.2.44±0.58mm，p＞0.05)，但LPEH患髋关节囊前、后层均较后二组有增厚趋势。3，LPEH患髋均存在关节腔内积液，且早期较为清晰；积液以髋关节内下间隙明显，内下间隙较前间隙明显增宽(12.50±4.04mm vs.4.35±0.8mm，p＜0.05)，其内见嵌顿滑膜唇皱襞呈稍强回声的占位性团块，长约15.6±5.6mm，宽约8.9±7.8mm，90.5％(19／21)嵌顿皱襞内未见血流信号。4，所有LPEH患髋治疗后超声复诊均显示正常。

While the tissue spaces surrounding a few blood vessels wasAl and Fg positive,no Al or Fg positive cells were observed.In antemortem injurygroup,diffuse subarachnoid hemorrhage,cerebral edema,swelling or pyknotic neu-rons could be observed.The axons showed irregular swelling and disconnection at1～3h,marked swelling and disconnection at 6h,and retraction ball at 15h whichwas more remarkable at 24h after injury.The space between myelin sheaths andaxons was increased at 3～6h after injury.Tortuous and wavelike myelin sheathswhich adhered on axons incompletely,or even peeled off could be found from 15hto 24h after injury.Perinuclear lysis of Nissl bodies began at 24h after injury.Thenumber of GFAP positive cells in cerebrum and brain-stem increased significantlyfollowed by decrease,and then increased again,but the time courses of the changesin different areas of brain were not same.Al and Fg positive neural cells,mainlysurrounded blood vessels,with diffuse or peripherally distributed positive matter incytoplasm could be observed at 0.5h after injury.The number of Al or Fg positivecells and the intensity of immunoreaction increased with the time of injury.The areaof SYN positivity in medulla oblongata and pons decreased notably 3～6h afterinjury,then return to normal levels and continued to 24h after injury.

生前损伤组，可见广泛蛛网膜下腔出血，脑组织水肿，神经细胞肿胀，晚期神经元固缩；伤后1～3h见部分神经轴突不规则增粗、断裂，伤后6h断端膨大，伤后15h可见收缩球，至伤后24h更为明显；伤后3～6h可见部分神经髓鞘与轴突之间的间隙增宽，伤后15h髓鞘明显曲折，不完全附着在轴突两侧，甚至剥脱，持续到伤后24h；核周尼氏体减少在伤后24h才开始出现；同一部位的GFAP阳性细胞数目随损伤时间发生改变，先增多（最早在伤后0.5h），达到高峰后减少，其后又有增多趋势，但不同部位的GFAP阳性细胞数目增减的时间过程不尽相同，同时，大脑中的GFAP阳性细胞数目也有改变；伤后0.5h，可在脑干组织中见到Al和Fg阳性神经细胞，主要位于血管周围，阳性物在胞浆中呈弥散性分布，但部分细胞的阳性物仅分布于靠近胞膜的胞浆中而呈环状，随损伤时间延长，阳性细胞数目增多，反应强度增加；伤后3～6h，延髓及桥脑中的SYN阳性物面积减少，其后恢复到正常水平，并持续到伤后24h。

The expressions of VEGF mRNA in renal cortex in B and group C increased greatly compared with A group at 8th week(P.01), And the expression was decreased more in C group than that in B group at the 8th week;④The light microscopes results showed that no pathological changes in group A; pathological changes were much obvious in group B:glomerular capillary lumen tumbling,lumens blocked,mesangial region widened,basal lamina thicking,mesenterium base inceased,the volume of glomerulus become large,cell population increased,renal tubule vacuolization, renal interstitium was infiltrated by lots of lymphocyte and mononuclear macrophage; pathological changes in group C was light,only see glomerular capillary lumen lightly stegnosis,few lymphocyte infiltrating.

免疫组化结果显示第8周B组大鼠肾皮质VEGF蛋白含量较A组显著增加(P.01)，C组VEGF含量较B组有明显减少(P.01)，C组较A组表达量仍然增加(P.01)；③第8周B组肾皮质VEGF mRNA表达较A组有明显上调(P.01)，与B组相比，辛伐他汀可以明显减少C组肾皮质VEGF mRNA表达；④光学显微镜下A组肾小球毛细血管腔均匀一致，无狭窄，肾小管-间质无炎症细胞浸润。B组则病变较明显：大鼠肾小球毛细血管袢塌陷，管腔闭塞，系膜区增宽，基膜增厚和系膜基质增多，肾小球体积增大，出现玻璃样变；肾小管尤其是近区小管肿胀、变性、空泡形成，肾间质可见大量淋巴细胞和单核巨噬细胞浸润。C组病变较轻，可见肾小球毛细血管管腔轻度狭窄，肾小管-间质见少量淋巴细胞浸润。

In 134 cases of infected pneumonia,100 cases showed patchy and puntual opacities in bilateral lung field,cloud margin of heart and diaphragm were seen in 20 cases,complicated pulmonary hemorrhage and heart failure were found in 14 cases.

结果：236例中，吸入性肺炎102例，其中表现为肺门增宽、肺纹理增粗的24例，表现为斑点状及斑片状阴影的68例，并发肺不张的10例；感染性肺炎134例，其中表现为双肺广泛点片状影的100例，表现为心缘及横膈边缘模糊的20例，并发肺出血及心力衰竭的14例。

Results: With the normal control group contrast, the HHD group has the varying degree cavity room to expand, with heart and soul expands 20 examples, the atrium sinistrum expands 49 examples, the left room expands 39 examples, the atrium dextrum expands 33 examples, the right room expands 24 examples, the pure atrium sinistrum expansion example number are most, reaches 11 examples, the room gap accumulation 24 examples, the left room behind accumulation 20 examples, the pulmonary artery inside diameter broadens 16 examples.

结果：与正常对照组对比，HHD组均有不同程度的腔室扩大，其中全心扩大20例，左房扩大49例，左室扩大39例，右房扩大33例，右室扩大24例，单纯左房扩大例数最多，达11例，室间隔增厚24例，左室后壁增厚20例，肺动脉内径增宽16例。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。