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Results The axial length of eyeball was gradually decreased during the adult years of life accompanying with the increases of corneal and lens refractive powers and a decrease of anterior chamber depth fur maintaining a emmetropia status, and the steepness and thickness of lens, shallowness of anterior chamber contributed to emmetropia by decreasing the refractive index of lens.

结果 随着年龄增大,眼轴逐渐变短,但同时伴有角膜、晶状体屈光力的增大及前房深度的变浅以维持正视状态,晶状体的增厚、曲率的变大及前房的变浅可能通过屈光指数的减小同样维持了正视状态。

The degradating and redistributing of ECM were migration of VSMC and vascular remodeling through inhibiting the production of PDGF-BB and the activation of MMPs so to prevent the vascular stenosis.⑤Orthotopic hybridism in situ: The expression of MMP-3 increased after operation, the tendency and intensity were parallel to the expression of NF-κB. Tongxinluo could decrease the expression of MMP-3 and NF-κB. The study showed that the producting and activating of MMP-3 were modulated by NF-κB. The inhibition to the producting and activating of MMp-3 of Tongxinluo was mediated by inhibiting the activating of NF-κB. Conclusion ①The rabbit vascular stenosis model could be established successfully by plain balloon damage, the operation process was easy, economical and practical.

①单纯球囊损伤可成功建立典型家兔血管狭窄模型,操作方法简单,经济实用;②以VSMC增殖、迁移为主的内膜增厚以及以ECM降解、合成与再分布所致的血管重构是导致受损血管狭窄的根本原因;③通心络能明显抑制VSMC的增殖、迁移和ECM降解、合成,阻止血管内膜增生和血管重构,防止受损血管狭窄;该作用可能与其减少和阻止PDGF-BB的产生和活性,以及抑制MMPs的表达和恢复MMPs/TIMPs平衡有关;④通心络能显著抑制球囊损伤后血管内膜增生和血管重构,可能与其保护血管内皮,改善内皮功能,增加血清NO含量有关;⑤通心络抑制内膜增生和血管重构,减轻受损血管狭窄,还可能是通过抑制NF-κB的活化途径而起作用的。

RESULT: 1.Ouabain act on lens sodium-pump,under the LM,lens anterior capsular membrane discontinuous,epithelium cells clustered,occluding zonule seperated,lens fiber layers fractured.Under the EM,cells totally hollowed,mitochondria swelling,myelin figure appeared.RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1、α2 and α3-isoform are all decreased.2.Digoxin act on lens sodium-pump,under the LM,lens cell oedema,linkage distructed,extensive exfoliation.Under the EM,plasma appeared little half-transparant hollow region,mitochondria swelling and ridge disappeared. RT-PCR examine,α1、α2 and α3-isoform are all decreased.3.Amphotericin B act on lens sodium-pump,under the LM,lens epithelium cells linked tightly,arranged in-line,lens fiber layers arranged tightly and regularily.Under the EM,abbundant cellular organes,exuberant cells function indicated. RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1 and α3-isoform are increased significantly,demonstrated isoform-specific action.4D-thyroxine act on lens sodium-pump,under the LM,lens plasmalemma integrated,cells arranged tightly and regularily.Under the EM,nucleus fission appeared,desmosome half-desmosome and tensile microfilaments linked the cells. RT-PCR examine,α2 and α3-isoform are increased, also demonstrated isoform-specific action.5.Vitamin E act on lens sodium-pump,under the LM,lens anterior capsular membrane continuous and smooth,epithelium cells tightly linked,lens fiber layers appearede hollow region occasionally.Under the EM,lateral membrane high density belt appeared,abundant nucleolus. RT-PCR examine,onlyα1-isoform are increased, demonstrated significantly isoform-specific action.6.DMSO act on lens sodium-pump,under the LM,lens anterior capsular membrane slightly thicker,cells linkage partly distructed.Under the EM,plasmalemma denaturation,mitochondria swelling.RT-PCR examine,α1、α2 and α3-isoform are all altered slightly and haven't significant meanning.

结果:1、哇巴因作用于晶状体钠泵后,光镜下晶状体前囊膜断裂、上皮细胞聚积、闭合连接分离、纤维板层裂隙,电镜下全层细胞空泡化、线粒体肿胀出现髓样结构,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。2、地高辛作用于晶状体钠泵后,光镜下晶状体细胞水肿、细胞连接破坏、广泛剥离,电镜下胞质见少许半透明空化区、线粒体肿胀嵴消失,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。3、两性霉素B作用于晶状体钠泵后,光镜下晶状体上皮细胞紧密连接、线状排列、纤维板层紧密规整,电镜下细胞器丰富、细胞功能旺盛,RT-PCR法检测α1及α3表达显著增强、具有一定的重整异构作用特异性。4、D甲状腺素作用于晶状体钠泵后,光镜下晶状体质膜完整、细胞排列紧密规整,电镜下胞核见分裂像、细胞间有桥粒、半桥粒及张力微丝,RT-PCR法检测α2及α3表达均增强、亦有一定的重整异构作用特异性。5、维生素E作用于晶状体钠泵后,光镜下晶状体前囊膜连续光滑、上皮细胞紧密连接、纤维板层偶见空化,电镜下囊侧膜内有高电子密度带、细胞核仁丰富,RT-PCR法检测仅有α1的表达显著增强、具有极强的重整异构作用特异性。6、二甲基亚砜作用于晶状体钠泵后,光镜下晶状体前囊膜轻度增厚、细胞连接部分破坏,电镜下质膜变性、线粒体肿胀,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达无显著改变。

There were some important discovery in structure character as the follows: in sarcotesta that materials making experiment, all possessed the structure of bandshape and like primary thickening meristem; sarcotesta possessed amphivasal vascular bundle and the vascular bundle that xylem distribute in two sied of phloem on inside and outside were discovered; new structure patterns of root that possessed more plentiful secondary cortex etc.

其中,发现外种皮中均具明显的似初生增厚分生组织的带状结构;且发现在外种皮的组织中具有双木维管束及周木维管束,发现了苏铁科植物根具较丰富的次生皮层等新的结构形式;在对比材料鳞秕泽米铁的羽片中发现了导管,这些在苏铁植物方面过去均未见有报道。

Between 6th and 14th weeks afteconstricted bilateral renal arteries, the blood pressure in the majority of RHRSP with cerebral infarction was obviously higher than in RHRSP without cerebral infarction (28. 8±2. 24kPa~32. 3 ±2. 88kPa, 26. 2±2. 01~28. 3±2. 33kPa respectively). Severe hyalinosis, fibrosis, wall hypertrophy, lumen stenosis, and even microaneurysm formation in cerebral small arteries in RHRSP with cerebral infarction were found, while slight to mild arteriolosclerosis in RHRSP was found without cerebral infarction.

本实验发现,RHRSP在经受不同水平的低血压后,产生脑梗塞的大多数(32/38只)在肾动脉狭窄术后第六周至第十四周,血压为28.8±2.24 kPa~32.3±2.88 kPa(216±17mmHg~242±22mmHg),显著高于无脑梗塞的RHRSP,并且发现这些RHRSP的脑内小血管呈严重的透明样变、纤维素样变性,管壁增厚,管腔狭窄,部分有微动脉瘤形成;而无脑梗塞的RHRSP的血压为26.2±2.01kPa~28.3±2.33 kPa(200±15mmHg~212±17.5mmHg),其脑内小血管呈轻至中度的动脉硬化改变。

On the basis of our series and the findings of Yapar et al, the sonographic features of pelvic TB may be categorized as wet type or dry type as follows. The wet type, found in 12 (75%) of 16 patients, is characterized by incompletely septated ascites, particulate ascites, loculated fluid (although clear ascites can also be commonly associated with tuberculous peritonitis ), a thickened peritoneum or omentum, and an adnexal mass, mimicking ovarian cancer; the dry type, found in a small number of cases, is characterized primarily by adnexal masses, adhesions, and loculated fluid, mimicking tubo-ovarian abscesses or complexes.

根据咱们和Yapar等人的发明,骨盆内部空腔TB的超声特征可以分为湿型或干型。16例病人中发明12例湿型TB,其特点是水臌内存在不完全的分隔、光点和多房性积液(尽管清亮的水臌通常也能归并结石性腹膜炎),和腹膜或网膜增厚和容易误诊成卵巢癌的附件团块;少量的病例呈干型TB,其特点主要是附件团块、粘连和多房性积液,象是输卵管-卵巢脓肿或复合体。

On the basis of our series and the findings of Yapar et al, the sonographic features of pelvic TB may be categorized as wet type or dry type as follows. The wet type, found in 12 (75%) of 16 patients, is characterized by incompletely septated ascites, particulate ascites, loculated fluid (although clear ascites can also be commonly associated with tuberculous peritonitis ), a thickened peritoneum or omentum, and an adnexal mass, mimicking ovarian cancer; the dry type, found in a small number of cases, is characterized primarily by adnexal masses, adhesions, and loculated fluid, mimicking tubo-ovarian abscesses or complexes.

根据我们和Yapar等人的发现,盆腔TB的超声特征可以分为湿型或干型。16例病人中发现12例湿型TB,其特点是腹水内存在不完全的分隔、光点和多房性积液(尽管清亮的腹水通常也能合并结核性腹膜炎),以及腹膜或网膜增厚和容易误诊成卵巢癌的附件团块;少量的病例呈干型TB,其特点主要是附件团块、粘连和多房性积液,象是输卵管-卵巢脓肿或复合体。

On the basis of our series and the findings of Yapar et al, the sonographic features of pelic TB may be categorized as wet type or dry type as follows. The wet type, found in 12 (75%) of 16 patients, is characterized by incompletely septated ascites, particulate ascites, loculated fluid (although clear ascites can also be commonly associated with tuberculous peritonitis ), a thickened peritoneum or omentum, and an adnexal mass, mimicking oarian cancer; the dry type, found in a small number of cases, is characterized primarily by adnexal masses, adhesions, and loculated fluid, mimicking tubo-oarian abscesses or complexes.

根据我们和Yapar等人的发现,盆腔TB的超声特征可以分为湿型或干型。16例病人中发现12例湿型TB,其特点是腹水内存在不完全的分隔、光点和多房性积液(尽管清亮的腹水通常也能合并结核性腹膜炎),以及腹膜或网膜增厚和容易误诊成卵巢癌的附件团块;少量的病例呈干型TB,其特点主要是附件团块、粘连和多房性积液,象是输卵管-卵巢脓肿或复合体。

Results 12 cases, there were 12 isolated subperiosteal hematoma of the skull, all in the top three weeks ~ March 2 cases, six months in March ~ 9 cases, one cases of more than half a year. 3 weeks to 3 months of hematoma, capsule machine was of uneven thickness of the line, a higher density strips; March ~ subcapsular hematoma of more than half a year with irregular thickening of the skull-shaped double-decker was changed after Hematoma shaping a longer period of time to become part of skull.

结果:12例中,共存在12个孤立的颅骨骨膜下血肿,全部位于顶部,3周~3月2例,3月~半年9例,半年以上1例。3周~3月的血肿,包膜机化呈厚薄不均的线状、条带状更高密度影; 3月~半年以上的血肿包膜不规则增厚与颅骨呈双层状改变,经过更长时间的塑形血肿成为颅骨的一部分结论: CT能准确诊断颅骨骨膜下血肿机化,并充分显示其大小、部位。

The growth mechanism of silver seed on silicon has been presented: at first, the silver monolayer and multilayer firstly grows onto silicon without fully covering the surface at the expense of silicon etching due to the silver seed attracting the electron from silicon, after that, the monolayer coalesces together, forming continuous grain film with some silver atoms diffusing into the silicon and the multilayer still grows thick simultaneously.

提出了银晶籽在硅表面的生长机理是:首先是在硅表面没有被完全覆盖的情况下,单层银晶籽生长的同时伴随有多层的生长,此后单层逐渐形成连续的薄膜,在单层晶籽层上多层薄膜逐渐增厚,并伴随有部分银原子向硅中的扩散。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

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