增加地

I am pleased to tell you that your year-end bonus has just grown by $750 for this suggesttion.

我很高兴地通知你，由于这项建议，你的年终奖金增加750美元。

I'm pleased to tell you that your year-end bonus has just grown by $750 for this suggestion.

我很高兴地通知你，由于这项建议，你的年终奖金增加750美元。

Slowly add in yolk one at the time.

慢慢地增加在蛋黄。

This proliferation of smaller polygons may be counteracted automatically by laying a small zone around each line.

更小的几何图形的增加也许自动地抵消由放置一个小区域在各条线附近。

The Na(superscript +) content increased accordantly with the NaCl concentration in culture solution. In young seedlings, Na(superscript +) content in root and root crown was higher than that in leaf; in germinating seeds, it was significantly higher in embryo than in testa and endosperm.

结果表明，随着培养液中NaC1浓度的增加，玉米体内Na含量逐渐升高，在幼苗中表现地下部显著高于地上部；在萌动种子中，胚中Na积累量显著高于种皮和胚乳。

Our results indicate that in Chinese Hans, common variants in CDKAL1,CDKN2A/B, IGF2BP2 and SLC30A8 loci independently or additively contribute to type 2 diabetes risk, likely mediated through β-cell dysfunction.

这些结果提示CDKAL1等基因上的SNP位点在中国汉族人群中能单独并共同地增加2型糖尿病发病风险，且可能是通过影响胰岛β细胞功能而实现的。

The results indicate that the introduction of alkoxy can greatly enhance the solubility of PPV in common organic solvents like THF, methylene chloride and so on.

结果表明，烷氧基取代基的引入显著地改善了PPV在THF和氯仿等一般有机溶剂中的可溶性，其可溶性随取代基长度的增加而提高。

Treatment of food allergy using very small but increasing daily doses of actual foods has been reported, 162 and in one controlled trial 163 12 of 14 patients successfully completed the program and could tolerate previously allergenic foods.

食物过敏的治疗用实际食品很小，但每天都在增加剂量据报道，162和对照试验的14例163 12 1成功地完成了程序，能够经受先前引起过敏的食物。

Enzymes of glycolysis (hexokinase,lactate dehydrogenase,aldolase) showed low activities during overwintering when more carbon flowing into treh alose synthesis.

越冬期间体内糖原磷酸化酶活性明显地增加，糖酵解有关的酶（己糖激酶、乳酸脱氢酶和醛缩酶）活性较低，以保证更多的碳源转化成海藻糖。

DCs acquired by our reformed methods express both CD83 and CD 14 molecules highly, and have a higher density than other domestic reports. The higher TNF in DCs culture medium of HC patient suggests DCs in patient still have antigen presenting ability and by optimization the culture medium would improve its presenting ability and have a potential value in design and application individual vaccine. Although antigens pulsed DCs have a decrescent antigen presenting ability but BCG HSP70 could induce its mature and improve its presenting ability. Suggests BCG HSP70 would be a useful mature inducer. Lymphocytes primed by DCs based HC vaccine have the specific cytotoxicity against HCC lines. The CTL after freezing and anabiotic could prophylaxis and therapy HC xenograft on nude mouse. The results also suggests that CD4〓 lymphocytes play a important role in HC with a good differentiation and would be useful in treatment this kind of HC. After being activated by Peptide LLNQHACAV of hAFP and apoptotic HCCs pulsed DCs respectively, the culture medium of activated lymphocytes both contains a high level Th1 cytokines IL-12 and TNF. Primed lymphocytes appeared a characteristic of NK cells. DCs not only inhibited the growth of human HCC and other cancer cells in vitro but also prevented the growth of HC xenograft on nude mouse in vivo. There are at least three kinds of mechanism playing important role in DC based vaccine ,there are inhibition of DCs, HC specific CTL and cytokines pathway.

诱导出的DC共同表达CD83和CD14分子，CD83分子表达明显高于国内报道；肝癌患者DC培养上清中TNF水平高于健康人，提示肝癌患者DC仍具一定的抗原呈递能力，适当调控可使其行使APC功能，以期在肝癌个体化疫苗中发挥作用；DC负载肝癌可溶性抗原后，抗原呈递能力降低，BCG HSP70可促进DC成熟，增加其抗原呈递能力，预示BCG HSP70有可能成为促进DC活化和成熟的另一重要分子；肝癌DC疫苗在体外诱导肝癌特异性淋巴细胞，活化的淋巴细胞在体外对肝癌细胞的杀伤以特异性CTL为主，同时分泌较高水平Th1型细胞因子IL-12和TNF，并抑制4种肝癌细胞生长；冷冻复苏后的肝癌特异性淋巴细胞可以预防和抑制人肝癌裸鼠皮下移植瘤，提示DC负载肝癌可溶性抗原后诱发的MHC-Ⅱ类限制性CD4〓T细胞有可能在分化程度高的肝癌治疗中发挥作用；用DC和HLA-A2〓DC分别负载凋亡肝癌细胞和hAFP218-226位LLNQHACAV HLA-A2限制性九肽，在体外诱导肝癌特异性淋巴细胞，活化后的CTL细胞分泌较高水平的Th1型细胞因子IL-12和TNF，并具较强杀伤活性，此CTL同时具备NK细胞特征；DC对肿瘤细胞的抑制作用可能是通过吞噬实现的，Fas-L在DC抑制中也起一定作用；DC对人肝癌裸鼠皮下移植瘤的抑制率为97％；在肝癌DC疫苗的作用中，至少联合3种以上机制，即通过DC的直接作用、肝癌特异性CTL和细胞因子途径直接或间接地杀伤和抑制肝癌细胞。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。